ASFVdb The African Swine Fever Virus Database
Strain
Ukraine_Kyiv_2014 (Region: Ukraine;  Strain: ASFV/Kyiv/2016/131;  Date: 2014)
Gene
G1211R
Description
Annotated in NCBI,  ASFV_Kyiv_2016_131_00144
GenBank Accession
Full name
DNA polymerase       + More
DNA polymerase beta      
DNA_pol_B_exo1 domain-containing protein      
DNA_pol_B domain-containing protein      
 

Sequence

CDS
ATGGGCTACAACACGGCCGCGGACGACACAACCTGTTATTACCGAATGGTTTCCCGAGAATTAAAACTACCTCTTACAAGTTGGATACAGCTTCAGCACTATTCCTACGAGCCTCGCGGCTTGGTACACAGGTTTTCCGTAACCCCCGAGGATCTTGTTTCCTATCAGAATGATGGCCCCACAGACCACAGCATCGTTATGGCCTACGATATAGAGACCTATAGCCCTGTTAAGGGAACCGTTCCGGACCCAAATCAGGCAAACGACGTGGTGTTCATGATATGCATGCGCATTTTTTGGATTCACTCCACAGAGCCTCTAGCGAGCACGTGCATCACCATGGCACCCTGCAAAAAGTCCTCAGAGTGGACCACCATTCTATGCTCCTCTGAAAAAATTTGTTGTTAA
Protein
MGYNTAADDTTCYYRMVSRELKLPLTSWIQLQHYSYEPRGLVHRFSVTPEDLVSYQNDGPTDHSIVMAYDIETYSPVKGTVPDPNQANDVVFMICMRIFWIHSTEPLASTCITMAPCKKSSEWTTILCSSEKICC

Summary

Function
DNA-directed DNA polymerase involved in viral DNA replication.
Catalytic Activity
a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
Miscellaneous
Consistent with its intracellular location, ASFV encodes its own replicative DNA polymerase and three base excision repair enzymes: a class II AP endonuclease, the repair polymerase Pol X, and an ATP-dependent DNA ligase.
Similarity
Belongs to the DNA polymerase type-B family.
Keywords
Complete proteome   DNA replication   DNA-binding   DNA-directed DNA polymerase   Nucleotidyltransferase   Reference proteome   Repeat   Transferase   Viral DNA replication  
Feature
chain  DNA polymerase beta
EC Number
2.7.7.7
EMBL
FR682468    CBW46756.1    MG939583    MG939587    MG939588    LS478113    + More
AXZ95864.1    AXZ96052.1    AXZ96147.1    SPS73513.1    KM111294    AJL34103.1    FN557520    CBH29190.1    AM712240    CAN10439.1    KM262844    KM262845    KP055815    KX354450    AIY22281.1    AIY22439.1    AKO62771.1    AOO54438.1    KM102979    AJZ77043.1    AM712239    CAN10189.1    L19042    U18466    AY261360    X73330    U27573    U27574    U27575    AY261366    AY261363    MN194591    QED21680.1    AY261361    KM111295    MH025916    MH025917    MH025918    MH025919    MH025920    AJL34268.1    AXB49318.1    AXB49492.1    AXB49664.1    AXB49835.1    AXB50008.1    LLXK01001105    PKY27357.1    LLXH01001253    PKC59830.1    LLXJ01004458    PKB95774.1    QKWP01001275    RIB10232.1    LLXI01001179    PKY52302.1    BDIQ01000006    GBC12123.1    LLXL01001655    PKK63436.1    BEXD01001864    GBB96059.1    PQFF01000070    RHZ84900.1    PQFF01000420    RHZ51250.1    BDIQ01000050    GBC19186.1    LLXJ01001653    PKC01275.1    PQFF01000480    RHZ47832.1    QKYT01000728    RIA81911.1    LLXL01008229    PKK54585.1    QKKE01000878    RGB24093.1    LLXL01003056    PKK59422.1    LLXH01003480    PKC54175.1    LLXI01005981    PKY61849.1    LLXI01005913    PKY61814.1    AUPC02000025    POG79363.1    AUPC02000146    POG68847.1    LLXJ01003907    PKB96421.1    BEXD01003317    GBC00820.1    BDIQ01000165    GBC48976.1    LLXI01001436    PKY53666.1    BEXD01000935    GBB91215.1    LLXH01001691    PKC57870.1    LLXI01002665    PKY57715.1    QKYT01000562    RIA83541.1    LLXL01003272    PKK58991.1    QKKE01000157    RGB36016.1    KI300872    ERZ95903.1    JEMT01030077    EXX50274.1    LLXJ01003171    PKB97499.1    BDIQ01000048    AUPC02000458    GBC18196.1    POG59303.1    QKWP01000028    RIB29843.1    BEXD01001755    GBB95616.1    QKWP01003150    RIB01390.1    LLXK01001680    PKY30162.1    QKWP01000598    RIB17554.1    LLXI01001387    PKY53442.1    LLXH01000952    LLXK01001701    PKC61656.1    PKY30249.1    LLXK01002565    LLXK01002567    PKY32612.1    PKY32615.1    BEXD01004337    GBC09907.1    LLXL01003040    PKK59461.1    AUPC02000243    POG64353.1    QKKE01001213    RGB22550.1    LLXJ01003543    PKB96922.1    LLXI01000255    PKY43459.1    LLXI01001309    PKY53010.1    LLXI01002763    PKY57922.1    PQFF01000543    RHZ45605.1    LLXL01006953    LLXL01006853    PKK55728.1    PKK55773.1    PQFF01000229    RHZ71983.1    LLXK01002822    PKY33086.1    LLXI01003073    PKY58554.1    LLXH01003046    PKC54699.1    QKWP01000098    RIB27451.1    LLXJ01002655    PKB98390.1    AUPC02000139    POG69262.1    LLXL01002239    PKK61378.1    PQFF01000194    RHZ76070.1    LLXL01000689    PKK69789.1    LLXI01005298    PKY61400.1    AUPC02000615    POG57794.1    LLXK01001451    PKY29136.1    QKKE01000596    RGB26652.1    BDIQ01000194    GBC52743.1    BDIQ01000191    GBC51647.1    JEMT01026038    EXX60121.1    LLXH01003557    PKC54086.1    QKYT01000515    RIA84139.1    QKKE01000210    RGB34234.1    LLXK01002284    PKY31988.1    LLXL01000571    PKK70870.1    BEXD01001158    GBB92641.1    QKYT01000159    RIA91221.1    QKYT01002176    RIA78745.1    BEXD01001613    GBB94948.1    QKWP01000454    RIB19785.1    QKWP01002014    RIB05266.1    QKYT01001161    RIA79750.1   
Pfam
PF03104   DNA_pol_B_exo1
PF00136   DNA_pol_B
Interpro
IPR006172   DNA-dir_DNA_pol_B
IPR017964   DNA-dir_DNA_pol_B_CS
IPR036397   RNaseH_sf
IPR023211   DNA_pol_palm_dom_sf
IPR006134   DNA-dir_DNA_pol_B_multi_dom
IPR012337   RNaseH-like_sf
IPR006133   DNA-dir_DNA_pol_B_exonuc
IPR042087   DNA_pol_B_C
SUPFAM
SSF53098   SSF53098
Gene 3D
PDB
6TNZ     E-value=4.66016e-23,     Score=272

Ontologies

KEGG

Subcellular Location

From MSLVP
Capsid

Topology

Length:
135
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.06252
Exp number, first 60 AAs:
0.00163
Total prob of N-in:
0.38288
outside
1  -  135
 
 

Population Genetic Test Statistics

Pi
0.0297703
Theta
0.0400208
Tajima's D
-0.7373078
CLR
0
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
AKO62771.1
China_AnhuiXCGQ_2018 Protein
AYW34061.1
China_ASFV-SY18_2018 Protein
AKO62771.1
Poland_Pol16_20186_o7_2016-2017 Protein
AXZ95864.1
Poland_Pol16_20538_o9_2016-2017 Protein
CAN10439.1
Poland_Pol16_20540_o10_2016-2017 Protein
CAN10439.1
Poland_Pol16_29413_o23_2016-2017 Protein
CAN10439.1
Poland_Pol17_03029_C201_2016-2017 Protein
AXZ96052.1
Poland_Pol17_04461_C210_2016-2017 Protein
AXZ96147.1
Poland_Pol17_05838_C220_2016-2017 Protein
CAN10439.1
Poland_ASFV_POL_Podlaskie_2015 Protein
CAN10439.1
Uganda_R8_2015 Protein
AXB49318.1
Uganda_R7_2015 Protein
AXB49492.1
Uganda_R25_2015 Protein
AXB49664.1
Uganda_N10_2015 Protein
AXB49835.1
Uganda_R35_2015 Protein
AXB50008.1
Estonia_2014 Protein
SPS73513.1
Italy_26544_OG10_2010 Protein
AJZ77043.1
Italy_47_Ss_2008_2008 Protein
AOO54438.1
Portugal_OURT_88.3_1988 Protein
Protein
CAN10439.1
CAN10439.1
Spain_E75_1975 Protein
CBH29190.1
Russia_Georgia_2007 Protein
CBW46756.1
Kenya_Tk1_2005 Protein
AJL34103.1
Kenya_Bus_2006 Protein
AJL34268.1
Russia_Odintsovo_2014 Protein
CAN10439.1
Portugal_L60_1960 Protein
AIY22281.1
Portugal_NHV_1968 Protein
AIY22439.1
Russia_Kashino_2013 Protein
CAN10439.1
Benin_1997 Protein
CAN10189.1
South_Africa_KNP_Pretorisuskop_1996 Protein
CAN10439.1
South_Africa_MGR_Mkuzi_1979 Protein
CAN10439.1
Malawi_Lil_1983 Protein
CAN10439.1
Kenya_1950 Protein
CAN10439.1
Namibia_Warthog_1980 Protein
CAN10439.1
South_Africa_Warmbaths_1987 Protein
CAN10439.1
Malawi_Tengani_1962 Protein
CAN10439.1
China_HLJ_2018 Protein
QBH90578.1
China_LN_2018 Protein
QBH90763.1
China_wbBS01_2018 Protein
QDL88121.1
Ukraine_Kyiv_2014 Protein
Protein
Protein
Protein
QED21679.1
QED21680.1
QED21681.1
QED21682.1
Belgium_Etalle_wb_2018 Protein
QED90533.1
Lithuania_LT14_2014 Protein
QEY87896.1
South_Africa_1985 Protein
QGM12923.1
South_Africa_2_2008 Protein
QGM12849.1
Zambia_LIV_1983 Protein
QGM12734.1
Copyright@ 2018-2023    Any Comments and suggestions mail to:  zhuzl@cqu.edu.cn, mg@cau.edu.cn   渝ICP备19006517号

渝公网安备 50010602502065号

In processing...
Login to ASFVdb
Email
Password
Please go to Regist if without an account.
If you have forgotten your password, you can once again Regist an account with a registed or new email.
Change my password
Enter new password
Reenter new password
Regist an account of ASFVdb
It is required that you provide your institutional e-mail address (with edu or org in the domain) as confirmation of your affiliation.
Enter email
Reenter email
First Name
Last Name
Institution
You can directly go to if with an account.
Registraion Success
Your password has been sent to your email.
Please check it and login later.
Welcome to use ASFVdb.