Strain

Poland_Pol16_20540_o10_2016-2017 (Region: Poland; Strain: Pol16_20540_o10; Date: 2016-2017)

Gene

C962R

Description

With frameshift mutation but translatable, C962R

Location

MG939585.1(+):89103-89480

GenBank Accession

QED21643.1

Full name

Putative helicase C962R

CDS

ATGCGCGAGGAATCATGGGAAGACCACGATACCATTCAGCTCACCGCTCAGCGCAAATACCTCGCCGAGGTGCAAGCTCTAGAGACCCTTTTGACTCGAGAGCTTTCAGTCTTTCTCACAGAGCCAGGCAGCAAAAAAACAAATATTATTAATAGAATCACAGGAAAAACCTACGCACTTCCCAGCACAGAGCTACTAAGACTCTACGAGCATCTCGAGCAATGTCGCAAGCAAGGCGCCCTCATGTATTTTTTGGAAAGACAGGGGACCTACTCGGGTCTCATGTTGGACTATGACCTTAAACTCAATACAAATGCTGTTCCCCCGCTGGAACCCCCCGCGCTATCACGGCTTTGCCATCGAATATTTGTGCATATA

Protein

MREESWEDHDTIQLTAQRKYLAEVQALETLLTRELSVFLTEPGSKKTNIINRITGKTYALPSTELLRLYEHLEQCRKQGALMYFLERQGTYSGLMLDYDLKLNTNAVPPLEPPALSRLCHRIFVHI

Similarity

Belongs to the asfivirus helicase C962R family.

Keywords

ATP-binding Complete proteome DNA replication Helicase Hydrolase Nucleotide-binding Reference proteome

Feature

chain Putative helicase C962R

Uniprot

A0A5B8XDQ6 D4I5Q9 P0C9X3 E0WMK9 A0A2X0TKI6 P0C9X1 + More
A9JLV6 A9JL24 A0A0A1E0M4 Q65162 Q8V9U4 P0C9X2 A0A0C5AZG0 A0A0C5B022

Pubmed

21470447 18198370 25406173 26618713 11831707 25645905 + More

EMBL

MN194591 QED21643.1 FN557520 CBH29172.1 AY261363 FR682468 + More
CBW46737.1 MG939583 MG939587 MG939588 LS478113 AXZ95845.1 AXZ96033.1 AXZ96128.1 SPS73494.1 AY261366 AM712240 CAN10420.1 AM712239 CAN10171.1 KM262844 KM262845 KM102979 KP055815 KX354450 AIY22263.1 AIY22421.1 AJZ77047.1 AKO62753.1 AOO54407.1 U18466 L00966 AY261361 AY261360 KM111294 AJL34085.1 KM111295 MH025916 MH025917 MH025918 MH025919 MH025920 AJL34250.1 AXB49300.1 AXB49474.1 AXB49646.1 AXB49817.1 AXB49990.1

Proteomes

UP000321214 UP000101090 UP000000859 UP000141072 UP000000858 UP000108903 + More
UP000130745 UP000110401 UP000117635 UP000142390 UP000241813 UP000266411 UP000000624 UP000000860 UP000000861 UP000105860 UP000101566

Pfam

PF08706 D5_N
PF08707 PriCT_2

Interpro

IPR014818   Phage/plasmid_primase_P4_C
IPR014015   Helicase_SF3_DNA-vir
IPR027417   P-loop_NTPase
IPR014819   PriCT_2

SUPFAM

SSF52540 SSF52540

ProteinModelPortal

A0A5B8XDQ6 D4I5Q9 P0C9X3 E0WMK9 A0A2X0TKI6 P0C9X1 + More
A9JLV6 A9JL24 A0A0A1E0M4 Q65162 Q8V9U4 P0C9X2 A0A0C5AZG0 A0A0C5B022

PDB

5X42 E-value=2.94147, Score=74

Ontologies

KEGG

vg:22220301

GO

GO:0006260  P:DNA replication
GO:0004386  F:helicase activity
GO:0005524  F:ATP binding
GO:0016817  F:hydrolase activity, acting on acid anhydrides

Subcellular Location

From MSLVP

Single-Pass Membrane

Topology

Length:

126

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00219

Exp number, first 60 AAs:

0.00145

Total prob of N-in:

0.28361

outside

1 - 126

Population Genetic Test Statistics

Pi

0.0224936

Theta

0.0364084

Tajima's D

-0.9249644

CLR

0.286211

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein Protein	QED21643.1 AKO62753.1
China_AnhuiXCGQ_2018	Protein Protein	QED21643.1 AYW34042.1
China_ASFV-SY18_2018	Protein Protein Protein	CBH29172.1 CBH29173.1 AKO62753.1
Poland_Pol16_20186_o7_2016-2017	Protein Protein	QED21643.1 AXZ95845.1
Poland_Pol16_20538_o9_2016-2017	Protein Protein	CAN10171.1 QED21643.1
Poland_Pol16_20540_o10_2016-2017	Protein Protein	CAN10171.1 QED21643.1
Poland_Pol16_29413_o23_2016-2017	Protein Protein	CAN10171.1 QED21643.1
Poland_Pol17_03029_C201_2016-2017	Protein Protein	QED21643.1 AXZ96033.1
Poland_Pol17_04461_C210_2016-2017	Protein Protein	QED21643.1 AXZ96128.1
Poland_Pol17_05838_C220_2016-2017	Protein Protein	CAN10171.1 QED21643.1
Poland_ASFV_POL_Podlaskie_2015	Protein Protein	CAN10171.1 QED21643.1
Uganda_R8_2015	Protein Protein	QED21643.1 AXB49300.1
Uganda_R7_2015	Protein Protein	QED21643.1 AXB49474.1
Uganda_R25_2015	Protein Protein	QED21643.1 AXB49646.1
Uganda_N10_2015	Protein Protein	QED21643.1 AXB49817.1
Uganda_R35_2015	Protein Protein	QED21643.1 AXB49990.1
Estonia_2014	Protein Protein	QED21643.1 SPS73494.1
Italy_26544_OG10_2010	Protein Protein	QED21643.1 AJZ77047.1
Italy_47_Ss_2008_2008	Protein Protein Protein	QED21643.1 AOO54407.1 AOO54408.1
Portugal_OURT_88.3_1988	Protein Protein	QED21643.1 CAN10420.1
Spain_E75_1975	Protein Protein	CBH29172.1 CBH29173.1
Russia_Georgia_2007	Protein Protein	QED21643.1 CBW46737.1
Kenya_Tk1_2005	Protein Protein	QED21643.1 AJL34085.1
Kenya_Bus_2006	Protein Protein	QED21643.1 AJL34250.1
Russia_Odintsovo_2014	Protein Protein	CAN10171.1 QED21643.1
Portugal_L60_1960	Protein Protein	QED21643.1 AIY22263.1
Portugal_NHV_1968	Protein Protein	QED21643.1 AIY22421.1
Russia_Kashino_2013	Protein Protein	CAN10171.1 QED21643.1
Benin_1997	Protein Protein Protein	CAN10171.1 QED21643.1 CAN10171.1
South_Africa_KNP_Pretorisuskop_1996	Protein Protein	CAN10171.1 QED21643.1
South_Africa_MGR_Mkuzi_1979	Protein Protein	CAN10171.1 QED21643.1
Malawi_Lil_1983	Protein Protein	CAN10171.1 QED21643.1
Kenya_1950	Protein Protein	CAN10171.1 QED21643.1
Namibia_Warthog_1980	Protein Protein	CAN10171.1 QED21643.1
South_Africa_Warmbaths_1987	Protein Protein	CAN10171.1 QED21643.1
Malawi_Tengani_1962	Protein Protein	CAN10171.1 QED21643.1
China_HLJ_2018	Protein Protein	QED21643.1 QBH90559.1
China_LN_2018	Protein Protein	QED21643.1 QBH90744.1
China_wbBS01_2018	Protein Protein	QED21643.1 QDL88102.1
Ukraine_Kyiv_2014	Protein Protein Protein	QED21643.1 QED21644.1 QED21645.1
Belgium_Etalle_wb_2018	Protein Protein	QED21643.1 QED90514.1
Lithuania_LT14_2014	Protein Protein	QED21643.1 QEY87877.1
South_Africa_1985	Protein Protein	QED21643.1 QGM12919.1
South_Africa_2_2008	Protein Protein	QED21643.1 QGM12844.1
Zambia_LIV_1983	Protein	QED21643.1

Sequence