ASFVdb The African Swine Fever Virus Database
Strain
Poland_Pol16_20186_o7_2016-2017 (Region: Poland;  Strain: Pol16_20186_o7;  Date: 2016-2017)
Gene
NP1450L
Description
Annotated in NCBI,  gene expression: late
GenBank Accession
Full name
DNA-directed RNA polymerase subunit      
 

Sequence

CDS
TTGAAGTTTTATTATGTATTTAGCAAAAATATGGAGGCTGGATATGCCGAAATAGCCGCCGTTCAGTTCAATATTGCCGGTGACAATGATCATAAGAGGCAAGGCGTTATGGAGGTTACCATTTCTAATTTATTTGAGGGCACCCTTCCCGCCGAAGGGGGTATCTATGATGCGCGAATGGGAACCACCGATCACCATTATAAATGCATCACTTGCTCACACCAGCGCAAGCAATGTATGGGACACCCTGGGATACTGCAGATGCATGCTCCGGTGCTTCAGCCGCTCTTCATCGCCGAAATACGACGATGGTTAAGGGTTATATGTCTCAACTGCGGGGCTCCCATCGTTGACCTAAAGAGGTACGAGCACCTTATTAGGCCTAAGCGTCTTATTGAAGCGGCTTCAAGCCAAACCGAAGGAAAGCAGTGCTACGTCTGTAAGGCAGTACACCCCAAAATTGTTAAGGACTCGGAAGATTATTTTACCTTTTGGGCGGATCAGCAGGGCAAGATTGACAAACTGTACCCGCAGATCATCAGAGAGATTTTTTCGCGCGTAACCTACGACACCGTTGTAAAACTGGGGCGAAGTAAAAACTCCCATCCCGAAAAACTTGTGCTTAAGGCCATTCAGATCCCCCCCATCAGCATACGACCTGGCATCAGATTGGGAATCGGGTCAGGCCCCCAAAGCTTTCACGACATTAACAACGTGATTCAGTATCTGGTTCGAAAGAATCTGCTGATCCCGAAGGACCTACAAATCGTGCGCGGCCAAAAAATACCTTTAAATATTGACCGCAATTTGCAAACCATACAGCAACTTTACTATAACTTTTTGTTGGATTCCGTTTCCACCACCGCAACCCAGGGAGGCACGGGAAAGCGTGGGATCGTCATGGGGGCACGCCCTGCTCCCTCCATCATGCGAAGACTTCCTCGCAAGGAGGGAAGAATTCGTAAATCCCTACTGGGCAGCCAGGTATGGTCGATCAGCCGGTCCACCATCTGCGGGAACTCAGACCTTCACCTGGACGAGGTTGGCTATCCCATTTCCTTTGCACGAACGCTGCAAGTTGCGGAAACAGTGCAACATTATAATATTAATAGATTAATGCCCTATTTTTTAAATGGAAAGCGCCAGTACCCTGGTTGTTCAAGAGTGTATAAGCAAATAACACAATCCGTTCACGACATTGAGGGTCTCAAACAAGACTTTAGGCTGGAGGTAGGAGACATCCTTTACCGTGACGTCGTCACTGGCGACGTCGCGTTTTTTAATCGCCAGCCTTCTCTCGAACGAAGCAGCATAGGGGTTCACCGGATTGTCGTTCTTGAAAACCCAAAAATTTCTACGTTTCAAATGAATGTCAGCGCATGTGCCTGGTATAATGCGGACTTTGACGGGGATCAGATGAATCTCTGGGTTCCCTGGAGCGTCATGAGCCGCGTTGAGGCCGAACTACTTTGTTCTGTGCGAAACTGGTTCATTTCCACAAAGAGCTCGGGTCCCGTTAATGGGCAGGTGCAGGACTCCACGGTGGGAAGCTTTTTGCTTACACGCACGAACACCCCCATGGGGAAAAATGTGATGAACAAGCTGCACGCCATGGGGTTGTTTCAAACAACCCAAACCGACCCACCTTGTTTTGCCAACTACTCCCCAACTGACCTGCTGGATGGCAAATCGGTTGTATCTATGCTACTGAGGCAGACCCCCATCAATTATCAACGAGCCCCCACATGGTACTCAGAAGTGTATGCACCCTACATGCATTATAACAAGCAGGACATCTCTACACAAATACGCAACGGCGAACTCATTGAAGGCGTCCTTGACAAAAAGGCCGTCGGAGCGGGTTCCTCCGGTGGAATCTATCACCTTATTTCGCGTAGGTATGGGCCGCAGCAGGCCTTGAAAATGATATTTGCGACCCAGCAGCTCGCCCTAAACTACGTGCGCAACGCCGGATTCACAGTGTCCACGGCCGACATGCTCCTAACCCCGGAGGCACATCAGGAGGTCCAAGAAATTATCAATGAACTGCTGCTTGAGTCGGAGGAAATAAACAACCGGCTGCTTCATGGAGACATCATGCCGCCTATAGGCCTGACAACGCATGACTTCTACGAAAAATTGCAGCTGAATGCGCTTAAATTTCCCGATAGAATTTTAAAGCCGATTATGAATTCCATTAATCCGGAAACCAATGGGCTTTTTCAGATGGTGGCCACTGGCGCCAAGGGCTCAAACCCCAATATGATTCACATCATGGCGGGCATCGGCCAAATTGAAATTAATACACAACGCATTCAACCCCAGTTTTCCTTCGGTAGGACCCTGGTGTACTACCCCAGGTTTGCCCTGGAGGCGCAGGCCTACGGGTTCATCTGCAACAGCTATATTGCGGGCCTTACCTCCCCTGAATTTATCTTTGGGGAAATGAATGGAAGATTCGACTTGATCAACAAAGCATTATCGACATCATCCACAGGCTATGCCAACCGTAAAGCCATCTTTGGCCTTCAATCCTGTATTGTGGATTATTACCGACGGGTTTCCATCGATACGCGTCTTGTGCAGCAGTTGTACGGAGAGGACGGCCTTGATGCGCGCCAGCTTGAAACCGTACGGTTTGAAACCATCATGCTGTCGGACCAGGAACTTGAAGACAAATTCAAGTACACCGGGATACAATCGCCCTTGTTTGAAGAAGAATTTTCACGCCTTAAAAAGGATAGAGATAAATATCGACAGATCTTCCTAAACGTCGAAAATTTTAATTTCAGTCAGCTGCTTACAGATGTTAGACAGGTGCCGGTAAACGTGGCCAGCATCGTAAAAAACATTCTACTGAGCTCCACCAGTGGCGTGCTTCCCTTCGACGAAAAAAGTATTCTACAAAAATACGCGATGGTCAAAACGTTTTGCAAAAATCTTCCATACGTGTTTATTAACAACATTCAGGAACGACTACAAACGCCCATACCCGTTTATCTTAAACGGGCTGCCTCTCTGATGCGCATGCTTATTCGCATCGAACTGGCAACCGTTAAAACATTAAACATTACCTGCGAGCAGATGAGTGCCATCCTGGACCTCATAAGGCTACAATATACTCAAAGTCTTATTAACTACGGTGAGGCAGTGGGAATCCTGGCGGCGCAGTCCGTATCAGAGCCCTTGACACAATATATGCTGGACTCCCACCACCGGTCCGTGGCCGGGGGAACCAACAAGTCGGGAATTGTGCGGCCCCAGGAGATCTTTAGCGCGAAGCCCGTAGAGGCTGAACAATCCTCTGAAATGCTTTTACGTCTAAAGAACCCGGAAGTGGAAACAAATAAAACATATGCGCAAGAAATTGCTAACAGCATAGAGCTTATAACGTTCGAACGGTTGATATTGCAGTGGCACCTATTGTACGAAACGTATTCAAGCACAAAAAAAAATGTGATGTACCCCGATTTTGCAAGTGATGTGGAATGGATGACGGATTTTCTGGAAAACCATCCTCTACTACAGCCCCCAGAGGATATTGCAAACTGGTGTATCCGCTTGGAATTAAACAAAACAACCATGATATTAAAAAGCATTAGTCTAGAAAGTATTATTAATAGTCTAAGAGCTAAACACCCCAACACCTACATCATGCATTCTGTGGAAAACACGGCCTCAGGGATTCCCATCATTATTCGCATATACCTACGGGAAAGCGCCTTTAGACGCAGTACCAATACCCGAATGGCTACGGATGAAAAAATTGCCGTAAATGTGGTGGATAAACTATTAAATAGCACGATTAGAGGAATACCAGGCATCAAAAATGCGAATGTTGTTAAGCTTATGCGCCACCGTGTGGATGCCCAGGGGAAACTGGTAAGACTAGACAATATCTACGCCATCAAAACAAACGGGACTAATATTTTTGGCGCAATGCTTGATGATAACATCGACCCATACACCATCGTATCGTCCTCTATAGGAGACACCATGGAGCTTTACGGCATAGAAGCGGCACGGCAAAAAATTATTAGTGAAATTAGAACGGTTATGGGGGACAAGGGTCCCAACCATCGTCATTTACTCATGTACGCAGATCTCATGACAAGAACGGGACAGGTTACCTCTCTAGAAAAGGCAGGGCTTAATGCAAGAGAGCCTTCCAACGTGTTGTTGCGAATGGCCTTGTCGTCTCCAGTCCAGGTCTTGACAGATGCTGCGGTTGACTCCGCCGTGAATCCCATTTACGGTATTGCCGCGCCTACCCTTATGGGCTCTGTTCCTCGCATAGGGACCATGTACTCTGACATCATTATGGATGAAAAATATATTACGGAAAATTATAAAAGTGTTGATTCCTTGATTGATATGTTATAG
Protein
MKFYYVFSKNMEAGYAEIAAVQFNIAGDNDHKRQGVMEVTISNLFEGTLPAEGGIYDARMGTTDHHYKCITCSHQRKQCMGHPGILQMHAPVLQPLFIAEIRRWLRVICLNCGAPIVDLKRYEHLIRPKRLIEAASSQTEGKQCYVCKAVHPKIVKDSEDYFTFWADQQGKIDKLYPQIIREIFSRVTYDTVVKLGRSKNSHPEKLVLKAIQIPPISIRPGIRLGIGSGPQSFHDINNVIQYLVRKNLLIPKDLQIVRGQKIPLNIDRNLQTIQQLYYNFLLDSVSTTATQGGTGKRGIVMGARPAPSIMRRLPRKEGRIRKSLLGSQVWSISRSTICGNSDLHLDEVGYPISFARTLQVAETVQHYNINRLMPYFLNGKRQYPGCSRVYKQITQSVHDIEGLKQDFRLEVGDILYRDVVTGDVAFFNRQPSLERSSIGVHRIVVLENPKISTFQMNVSACAWYNADFDGDQMNLWVPWSVMSRVEAELLCSVRNWFISTKSSGPVNGQVQDSTVGSFLLTRTNTPMGKNVMNKLHAMGLFQTTQTDPPCFANYSPTDLLDGKSVVSMLLRQTPINYQRAPTWYSEVYAPYMHYNKQDISTQIRNGELIEGVLDKKAVGAGSSGGIYHLISRRYGPQQALKMIFATQQLALNYVRNAGFTVSTADMLLTPEAHQEVQEIINELLLESEEINNRLLHGDIMPPIGLTTHDFYEKLQLNALKFPDRILKPIMNSINPETNGLFQMVATGAKGSNPNMIHIMAGIGQIEINTQRIQPQFSFGRTLVYYPRFALEAQAYGFICNSYIAGLTSPEFIFGEMNGRFDLINKALSTSSTGYANRKAIFGLQSCIVDYYRRVSIDTRLVQQLYGEDGLDARQLETVRFETIMLSDQELEDKFKYTGIQSPLFEEEFSRLKKDRDKYRQIFLNVENFNFSQLLTDVRQVPVNVASIVKNILLSSTSGVLPFDEKSILQKYAMVKTFCKNLPYVFINNIQERLQTPIPVYLKRAASLMRMLIRIELATVKTLNITCEQMSAILDLIRLQYTQSLINYGEAVGILAAQSVSEPLTQYMLDSHHRSVAGGTNKSGIVRPQEIFSAKPVEAEQSSEMLLRLKNPEVETNKTYAQEIANSIELITFERLILQWHLLYETYSSTKKNVMYPDFASDVEWMTDFLENHPLLQPPEDIANWCIRLELNKTTMILKSISLESIINSLRAKHPNTYIMHSVENTASGIPIIIRIYLRESAFRRSTNTRMATDEKIAVNVVDKLLNSTIRGIPGIKNANVVKLMRHRVDAQGKLVRLDNIYAIKTNGTNIFGAMLDDNIDPYTIVSSSIGDTMELYGIEAARQKIISEIRTVMGDKGPNHRHLLMYADLMTRTGQVTSLEKAGLNAREPSNVLLRMALSSPVQVLTDAAVDSAVNPIYGIAAPTLMGSVPRIGTMYSDIIMDEKYITENYKSVDSLIDML

Summary

Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic Activity
a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)
Similarity
Belongs to the RNA polymerase beta' chain family.
EC Number
2.7.7.6
Pfam
PF05000   RNA_pol_Rpb1_4
PF04983   RNA_pol_Rpb1_3
PF04998   RNA_pol_Rpb1_5
PF00623   RNA_pol_Rpb1_2
PF04997   RNA_pol_Rpb1_1
PF04990   RNA_pol_Rpb1_7
PF04992   RNA_pol_Rpb1_6
Interpro
IPR007066   RNA_pol_Rpb1_3
IPR000722   RNA_pol_asu
IPR007081   RNA_pol_Rpb1_5
IPR038593   RNA_pol_Rpb1_7_sf
IPR038120   Rpb1_funnel_sf
IPR007083   RNA_pol_Rpb1_4
IPR007073   RNA_pol_Rpb1_7
IPR006592   RNA_pol_N
IPR007080   RNA_pol_Rpb1_1
IPR036844   Hint_dom_sf
IPR004042   Intein_endonuc
IPR007075   RNA_pol_Rpb1_6
IPR006141   Intein_N
IPR000684   RNA_pol_II_repeat_euk
SUPFAM
SSF51294   SSF51294
Gene 3D
PDB
6J51     E-value=4.64905e-133,     Score=1221

Ontologies

Subcellular Location

From MSLVP
Cytoplasm

Topology

Length:
1460
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.07299
Exp number, first 60 AAs:
0.00389
Total prob of N-in:
0.00088
outside
1  -  1460
 
 

Population Genetic Test Statistics

Pi
0.0283267
Theta
0.0386839
Tajima's D
-0.8612052
CLR
0.038265
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
AKO62780.1
China_AnhuiXCGQ_2018 Protein
AYW34070.1
China_ASFV-SY18_2018 Protein
AKO62780.1
Poland_Pol16_20186_o7_2016-2017 Protein
AXZ95873.1
Poland_Pol16_20538_o9_2016-2017 Protein
CBW46765.1
Poland_Pol16_20540_o10_2016-2017 Protein
CBW46765.1
Poland_Pol16_29413_o23_2016-2017 Protein
CBW46765.1
Poland_Pol17_03029_C201_2016-2017 Protein
CBW46765.1
Poland_Pol17_04461_C210_2016-2017 Protein
AXZ96156.1
Poland_Pol17_05838_C220_2016-2017 Protein
CBW46765.1
Poland_ASFV_POL_Podlaskie_2015 Protein
CBW46765.1
Uganda_R8_2015 Protein
AXB49327.1
Uganda_R7_2015 Protein
AXB49501.1
Uganda_R25_2015 Protein
AXB49673.1
Uganda_N10_2015 Protein
AXB49844.1
Uganda_R35_2015 Protein
AXB50017.1
Estonia_2014 Protein
SPS73522.1
Italy_26544_OG10_2010 Protein
AJZ77039.1
Italy_47_Ss_2008_2008 Protein
AOO54449.1
Portugal_OURT_88.3_1988 Protein
CAN10448.1
Spain_E75_1975 Protein
CBH29199.1
Russia_Georgia_2007 Protein
Protein
CBW46765.1
CBW46765.1
Kenya_Tk1_2005 Protein
AJL34112.1
Kenya_Bus_2006 Protein
AJL34277.1
Russia_Odintsovo_2014 Protein
CBW46765.1
Portugal_L60_1960 Protein
AIY22290.1
Portugal_NHV_1968 Protein
AIY22448.1
Russia_Kashino_2013 Protein
CBW46765.1
Benin_1997 Protein
CAN10198.1
South_Africa_KNP_Pretorisuskop_1996 Protein
CBW46765.1
South_Africa_MGR_Mkuzi_1979 Protein
CBW46765.1
Malawi_Lil_1983 Protein
CBW46765.1
Kenya_1950 Protein
CBW46765.1
Namibia_Warthog_1980 Protein
CBW46765.1
South_Africa_Warmbaths_1987 Protein
CBW46765.1
Malawi_Tengani_1962 Protein
CBW46765.1
China_HLJ_2018 Protein
QBH90587.1
China_LN_2018 Protein
QBH90772.1
China_wbBS01_2018 Protein
QDL88130.1
Ukraine_Kyiv_2014 Protein
Protein
Protein
Protein
QED21693.1
QED21694.1
QED21695.1
QED21696.1
Belgium_Etalle_wb_2018 Protein
QED90542.1
Lithuania_LT14_2014 Protein
QEY87905.1
South_Africa_1985    
South_Africa_2_2008    
Zambia_LIV_1983    
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