Strain

Ukraine_Kyiv_2014 (Region: Ukraine; Strain: ASFV/Kyiv/2016/131; Date: 2014)

Gene

P1192R

Description

Annotated in NCBI, ASFV_Kyiv_2016_131_00183

Location

MN194591.1(+):151588-152787

GenBank Accession

QED21719.1

CDS

ATGCAGGATCCCCAAGATACATCAGTGTGCAGCTTGCGTCTGAATTTATTAAAACAATGTTCCCCGCGGAGGACTCATGGCTTCTCCCCCTACGTCTTTGAGGACGGCCAGCGGGCGGAACCAGAGTACTACGTGCCTGTGTTGCCGCTTGCTATTATGGAGTACGGCGCCAACCCATCGGAGGGCTGGAAGTACACCACTTGGGCCCGGCAACTGGAAGACATTTTGGCCTTGGTGAGGGCCTACGTCGACAAAGACAACCCAAAACACGAGCTACTGCACTATGCAATAAAACATAAGATTACTATACTCCCGCTGCGGCCCTCCAATTACAATTTCAAGGGCCATTTGAAGCGGTTTGGCCAATACTACTACAGCTACGGCACGTACGTCATCTCAGAGCAGCGAAATATAATTACTATTACGGAGCTTCCTCTGCGTGTTCCTACGGTTGCATACATCGAAAGTATAAAAAAATCGAGTAACCGCATGACATTTATTGAAGAAATCATCGACTACAGTAGTTCAGAAACTATTGAAATTCTGGTGAAATTAAAGCCAAATAGTCTTAACCGTATCGTGGAAGAATTTAAGGAGACTGAAGAGCAAGATTCCATAGAAAATTTTCTGCGCCTGCGCAATTGTTTACATTCACATCTAAACTTTGTAAAACCTAAAGGTGGCATTATCGAGTTTAACACGTATTATGAAATTTTGTATGCGTGGCTACCTTACAGGCGTGAGCTTTACCAAAAGCGTCTTATGCGTGAGCACGCGGTGCTTAAGCTGCGCATTATCATGGAAACTGCTATTGTACGCTACATCAATGAGTCTGCAGAGCTAAATCTTTCCCATTATGAGGATGAAAAGGAGGCAAGCCGCATTCTAAGCGAGCATGGATTTCCCCCGCTGAACCACACGCTGATCATTTCCCCTGAGTTTGCCTCTATAGAGGAACTCAATCAAAAAGCACTGCAGGGCTGTTATACCTATATACTATCTTTGCAGGCTCGAGAATTGCTTATCGCAGCCAAAACTCGTCGGGTGGAAAAAATAAAAAAAATGCAAGCTCGTCTTGATAAGGTTGAGCAGCTTTTGCAAGAGTCTCCCTTTCCCGGCGCCAGCGTATGGCTGGAGGAAATTGATGCGGTGGAAAAGGCTATTATAAAAGGAAGAAATACTCAGTGGAAATTTCATTAA

Protein

MQDPQDTSVCSLRLNLLKQCSPRRTHGFSPYVFEDGQRAEPEYYVPVLPLAIMEYGANPSEGWKYTTWARQLEDILALVRAYVDKDNPKHELLHYAIKHKITILPLRPSNYNFKGHLKRFGQYYYSYGTYVISEQRNIITITELPLRVPTVAYIESIKKSSNRMTFIEEIIDYSSSETIEILVKLKPNSLNRIVEEFKETEEQDSIENFLRLRNCLHSHLNFVKPKGGIIEFNTYYEILYAWLPYRRELYQKRLMREHAVLKLRIIMETAIVRYINESAELNLSHYEDEKEASRILSEHGFPPLNHTLIISPEFASIEELNQKALQGCYTYILSLQARELLIAAKTRRVEKIKKMQARLDKVEQLLQESPFPGASVWLEEIDAVEKAIIKGRNTQWKFH

Uniprot

A0A5B8XEQ4 A0A5E4J190

EMBL

MN194591 QED21719.1 CABMDW010000022 VVB70126.1

Proteomes

UP000321214

Pfam

PF00521 DNA_topoisoIV
PF16898 TOPRIM_C

Interpro

IPR013758   Topo_IIA_A/C_ab
IPR002205   Topo_IIA_A/C
IPR013757   Topo_IIA_A_a_sf
IPR013760   Topo_IIA-like_dom_sf
IPR031660   TOPRIM_C
IPR013759   Topo_IIA_B_C

SUPFAM

SSF56719 SSF56719

Gene 3D

1.10.268.10 3.90.199.10 3.40.50.670

ProteinModelPortal

A0A5B8XEQ4 A0A5E4J190

PDB

4GFH E-value=1.48562e-78, Score=750

Ontologies

GO

GO:0016853 F:isomerase activity

Subcellular Location

From MSLVP

Capsid

Topology

Length:

399

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0409

Exp number, first 60 AAs:

0.00069

Total prob of N-in:

0.01908

outside

1 - 399

Population Genetic Test Statistics

Pi

0.0411729

Theta

0.0489238

Tajima's D

-0.5090457

CLR

0.053486

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein	AKO62793.1
China_AnhuiXCGQ_2018	Protein	AYW34083.1
China_ASFV-SY18_2018	Protein	AKO62793.1
Poland_Pol16_20186_o7_2016-2017	Protein	AXZ95885.1
Poland_Pol16_20538_o9_2016-2017	Protein	CAN10212.1
Poland_Pol16_20540_o10_2016-2017	Protein	CAN10212.1
Poland_Pol16_29413_o23_2016-2017	Protein	CAN10212.1
Poland_Pol17_03029_C201_2016-2017	Protein	CAN10212.1
Poland_Pol17_04461_C210_2016-2017	Protein	AXZ96168.1
Poland_Pol17_05838_C220_2016-2017	Protein	CAN10212.1
Poland_ASFV_POL_Podlaskie_2015	Protein	CAN10212.1
Uganda_R8_2015	Protein	AXB49341.1
Uganda_R7_2015	Protein	AXB49515.1
Uganda_R25_2015	Protein	AXB49687.1
Uganda_N10_2015	Protein	AXB49858.1
Uganda_R35_2015	Protein	AXB50031.1
Estonia_2014	Protein	SPS73535.1
Italy_26544_OG10_2010	Protein	AJZ77044.1
Italy_47_Ss_2008_2008	Protein	AOO54473.1
Portugal_OURT_88.3_1988	Protein	CAN10461.1
Spain_E75_1975	Protein	CBH29212.1
Russia_Georgia_2007	Protein	CBW46778.1
Kenya_Tk1_2005	Protein	AJL34125.1
Kenya_Bus_2006	Protein	AJL34290.1
Russia_Odintsovo_2014	Protein	CAN10212.1
Portugal_L60_1960	Protein	AIY22303.1
Portugal_NHV_1968	Protein	AIY22461.1
Russia_Kashino_2013	Protein	CAN10212.1
Benin_1997	Protein Protein	CAN10212.1 CAN10212.1
South_Africa_KNP_Pretorisuskop_1996	Protein	CAN10212.1
South_Africa_MGR_Mkuzi_1979	Protein	CAN10212.1
Malawi_Lil_1983	Protein	CAN10212.1
Kenya_1950	Protein	CAN10212.1
Namibia_Warthog_1980	Protein	CAN10212.1
South_Africa_Warmbaths_1987	Protein	CAN10212.1
Malawi_Tengani_1962	Protein	CAN10212.1
China_HLJ_2018	Protein	QBH90600.1
China_LN_2018	Protein	QBH90785.1
China_wbBS01_2018	Protein	QDL88143.1
Ukraine_Kyiv_2014	Protein Protein Protein Protein	QED21716.1 QED21717.1 QED21718.1 QED21719.1
Belgium_Etalle_wb_2018	Protein	QED90555.1
Lithuania_LT14_2014	Protein	QEY87918.1
South_Africa_1985	Protein	QGM12932.1
South_Africa_2_2008	Protein	QGM12858.1
Zambia_LIV_1983

Sequence