ASFVdb The African Swine Fever Virus Database
Strain
Ukraine_Kyiv_2014 (Region: Ukraine;  Strain: ASFV/Kyiv/2016/131;  Date: 2014)
Gene
MGF_505-2R
Description
Annotated in NCBI,  ASFV_Kyiv_2016_131_00044
Location
MN194591.1(+):34785-36335
GenBank Accession
QED21580.1
Full name
Protein MGF 505-2R       + More
Protein MGF 505-10R      
Protein MGF 505-5R      
Protein MGF 505-7R      
Protein MGF 505-4R      
Protein MGF 505-6R      
Protein MGF 505-9R      
Protein MGF 505-1R      
 

Sequence

CDS
ATGTTTTCCCTTCAAGACCTTTGCCGAAAGCATCTTTTTATTCTTCCCGATGTTTTTGGCGAGCATGTACTACAACGATTAGGACTGTATTGGAGATGTCACGGCTCCCTTCAACGCATAGGAGACGACCACATACTCATACGACGGGATCTCATCCTTTCCACCAACGAGGCCTTAAGAATGGCGGGAGAGGAAGGAAACAATGAAGTAGTAAAGCTCTTGTTACTGTGGAAGGGAAATCTTCATTACGCCGTCATAGGAGCCTTGCAGGGTGATCAATATGACCTGATCCATAAGTATGAAAACCAAATCGGCGACTTTCATTTTATCTTACCATTGATTCAAGACGCGAATACGTTTGAAAAATGCCACGCTTTAGAACGTTTTTGTGGTGTTTCATGTCTGCTAAAACATGCTACAAAATACAACATGCTCCCTATTCTCCAAAAATACCAAGAAGAGCTGTCTATGAGAGCGTATCTTCACGAAACCCTATTTGAACTAGCATGCCTATGGCAGAGGTATGATGTCCTTAAATGGATAGAGCAAACCATACATGTTTACGACCTAAAGATTATGTTTAATATTGCCATCTCCAAGAGGGATCTGACTATGTACTCCTTAGGATATATTTTCCTTTTTGATAGAGGGAACACCGAAGCTACGTTGCTAACGCAACATCTCAAGAAGACAGCGGCCAAAGGGCTCCTCCACTTTGTGCTAGAAACGTTAAAATACGGCGGCAACATAGATACCGTCCTGACCCAAGCCGTAAAGTACAATCATAGAAAACTTTTAGATTATTTTCTGCGTCAACTACCTCGTAAACATATTGAAAAACTTTTGTTGCTGGCCGTGCAGGAAAAGGCTTCTAAAAAAACATTGAACTTACTGTTGTCACATTTAAACTACTCCGTGAAACGCATCAAAAAACTACCGCGCTATGTGATAGAGTACGAGTCCACCTTGGTGATAAAGATTTTATTAAAAAAAAGAGTGAACCTGATAGATGCCATGTTGGAAAAGATGGTAAGATATTTTTCTGCGACGAAAGTGAGGACGATCATGGATGAGCTTTCGATTAGTCCGGAAAGAGTCATTAAGATGGCTATACAGAAAATGAGAACGGATATCGTAATCCATACTTCTTATGTTTGGGAGGATGATCTAGAACGTCTTACTCGTCTTAAAAATATGGTATACACCATAAAGTACGAACATGGGAAAAAAATGTTAATTAAAGTCATGCACGGCATATACAAAAACTTATTATACGGCGAAAGGGAAAAAGTCATGTTTTATTTAGCCAAGCTCTATGTTGCTCAAAACGCGGCCACCCAATTCAGAGACATTTGTAAGGACTGTTACAAACTGGATGTGGCACGGTTTAAACCGCGGTTTAAGCAACTAATATTAGACTGTTTAGAAATTATTACTAAAAAATCTTGCTATAGTATCCTGGAAATCTTAGAAAAACATATTATTTCCCTGTTTACTATGAAAGTTATGACTGAAGAAGAAAAAAAACCTATGTTTAGAAATATTATATAA
Protein
MFSLQDLCRKHLFILPDVFGEHVLQRLGLYWRCHGSLQRIGDDHILIRRDLILSTNEALRMAGEEGNNEVVKLLLLWKGNLHYAVIGALQGDQYDLIHKYENQIGDFHFILPLIQDANTFEKCHALERFCGVSCLLKHATKYNMLPILQKYQEELSMRAYLHETLFELACLWQRYDVLKWIEQTIHVYDLKIMFNIAISKRDLTMYSLGYIFLFDRGNTEATLLTQHLKKTAAKGLLHFVLETLKYGGNIDTVLTQAVKYNHRKLLDYFLRQLPRKHIEKLLLLAVQEKASKKTLNLLLSHLNYSVKRIKKLPRYVIEYESTLVIKILLKKRVNLIDAMLEKMVRYFSATKVRTIMDELSISPERVIKMAIQKMRTDIVIHTSYVWEDDLERLTRLKNMVYTIKYEHGKKMLIKVMHGIYKNLLYGEREKVMFYLAKLYVAQNAATQFRDICKDCYKLDVARFKPRFKQLILDCLEIITKKSCYSILEILEKHIISLFTMKVMTEEEKKPMFRNII

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Similarity
Belongs to the asfivirus MGF 505 family.
Keywords
Complete proteome   Reference proteome   ANK repeat   Repeat  
Feature
chain  Protein MGF 505-2R
Uniprot
A0A5B8XAP8   E0WMG1   A0A2X0RU65   A9JKV3   A0A0A1E2Z4   Q89702   + More
D4I5L3   P0C9S8   P0C9S9   Q65128   A0A0C5B227   A0A2Z5DEX1   A0A0C5B2F7   P0C9S7   Q65114   A0A0C5AWL2   A0A3Q9CZE4   A0A1C6ZXX4   E0WMG9   A0A2X0TKE5   P0C9V0   A0A0C5AZ79   A0A0C5AYV0   A0A2Z5DF55   A0A0C5AW92   P0C9V1   P0C9V2   D4I5M0   A0A0A1DY08   A9JLM1   A9JKW5   A0A0A1E0I6   Q89869   P0C9T6   E0WMG5   A0A2X0TC45   A0A385KLZ1   P0C9T8   A9JKV8   D4I5L6   A0A0A1E043   Q89777   A0A0A1E0Y6   A9JLL5   A0A385KLZ6   E0WMG4   A0A2X0RVA3   P0C9T9   E0WMG7   A0A2X0RTS3   P0C9T7   P0C9U4   A0A5B8XAP5   D4I5L8   P0C9T5   P0C9T2   A0A0C5BC47   P0C9T3   A0A0C5BCK1   A0A2Z5DEF5   A0A0A1DY94   A9JLL8   P0C9T4   P0C9U5   P0C9U1   A9JKV6   D4I5L5   A9JLL3   A0A0A1E0I1   Q89768   A9JKW0   D4I5L7   A9JLL7   A0A0A1E0L2   Q89925   A0A0N7CQW3   A0A3G1EUV7   A9JKW2   A0A0A1E2Z7   E0WMG6   A0A2X0S742   P0C9U3   P0C9U2   A0A0C5AZC1   P0C9U0   A0A0C5AZV5   A0A2Z5DFS5   A9JKW3   D4I5L9   A9JLM0   A0A0A1DXI4   Q89740   P0C9S6   P0C9U7   P0C9U8   A0A0C5B2F2   A0A0C5AYU4   A0A2Z5DGS0   P0C9U9   P0C9S5  
Pubmed
21470447    18198370    25406173    26618713    11831707    8030263    + More
25645905    30547827   
EMBL
MN194591    QED21580.1    FR682468    CBW46689.1    MG939583    MG939587    + More
MG939588    LS478113    AXZ95802.1    AXZ95990.1    AXZ96085.1    SPS73446.1    AM712239    CAN10124.1    KM262844    KM102979    KP055815    KX354450    AIY22216.1    AJZ77062.1    AKO62707.1    AOO54349.1    U02468    U18466    FN557520    CBH29126.1    AY261363    AY261366    U03762    AY261361    KM111294    AJL34041.1    MH025916    MH025917    MH025918    MH025919    MH025920    AXB49255.1    AXB49429.1    AXB49601.1    AXB49773.1    AXB49945.1    KM111295    AJL34206.1    AY261360    U03761    AJL34209.1    AXB49258.1    AXB49432.1    AXB49604.1    AXB49775.1    AXB49948.1    MH910496    AZP54156.1    AJZ77055.1    AOO54359.1    CBW46697.1    AXZ95809.1    AXZ95997.1    AXZ96092.1    SPS73454.1    AJL34212.1    AJL34047.1    AXB49261.1    AXB49435.1    AXB49607.1    AXB49778.1    AXB49951.1    AJL34044.1    CBH29133.1    KM262845    AIY22382.1    AM712240    CAN10380.1    CAN10131.1    AIY22223.1    AKO62714.1    CBW46693.1    SPS73450.1    AXZ95806.1    AXZ95994.1    AXZ96089.1    CAN10127.1    CBH29129.1    AIY22219.1    AJZ77066.1    AKO62710.1    AOO54354.1    AIY22378.1    CAN10376.1    AXZ95805.1    CBW46692.1    AXZ95993.1    AXZ96088.1    SPS73449.1    CBW46695.1    SPS73452.1    QED21582.1    CBH29131.1    AJL34043.1    AJL34208.1    AXB49257.1    AXB49431.1    AXB49603.1    AXB49947.1    AIY22380.1    CAN10378.1    CAN10126.1    CBH29128.1    CAN10375.1    AIY22218.1    AIY22377.1    AJZ77065.1    AKO62709.1    AOO54353.1    CAN10128.1    CBH29130.1    CAN10377.1    AIY22220.1    AIY22379.1    AJZ77060.1    AKO62711.1    AOO54355.1    AKO62712.1    AOO54356.1    CAN10129.1    AIY22221.1    AJZ77061.1    CBW46694.1    AXZ95807.1    AXZ95995.1    AXZ96090.1    SPS73451.1    AJL34045.1    AJL34210.1    AXB49259.1    AXB49433.1    AXB49605.1    AXB49776.1    AXB49949.1    CAN10130.1    CBH29132.1    CAN10379.1    AIY22222.1    AIY22381.1    AJZ77064.1    AKO62713.1    AOO54358.1    AJL34201.1    AJL34037.1    AXB49251.1    AXB49425.1    AXB49597.1    AXB49770.1    AXB49941.1   
Proteomes
UP000321214    UP000141072    UP000130745    UP000117635    UP000142390    UP000241813    + More
UP000266411    UP000000624    UP000101090    UP000000859    UP000000858    UP000000860    UP000105860    UP000101566    UP000000861    UP000110401    UP000108903   
PRIDE
Q89702    Q65128    P0C9S7    Q65114    P0C9V0    P0C9V1    + More
P0C9V2    P0C9U4    P0C9U5    Q89925    P0C9U2    P0C9U0    P0C9S6    P0C9S5   
Pfam
PF03158   DUF249
Interpro
IPR004858   MGF_505
IPR036770   Ankyrin_rpt-contain_sf
SUPFAM
SSF48403   SSF48403
Gene 3D
1.25.40.20    
ProteinModelPortal
A0A5B8XAP8   E0WMG1   A0A2X0RU65   A9JKV3   A0A0A1E2Z4   Q89702   + More
D4I5L3   P0C9S8   P0C9S9   Q65128   A0A0C5B227   A0A2Z5DEX1   A0A0C5B2F7   P0C9S7   Q65114   A0A0C5AWL2   A0A3Q9CZE4   A0A1C6ZXX4   E0WMG9   A0A2X0TKE5   P0C9V0   A0A0C5AZ79   A0A0C5AYV0   A0A2Z5DF55   A0A0C5AW92   P0C9V1   P0C9V2   D4I5M0   A0A0A1DY08   A9JLM1   A9JKW5   A0A0A1E0I6   Q89869   P0C9T6   E0WMG5   A0A2X0TC45   A0A385KLZ1   P0C9T8   A9JKV8   D4I5L6   A0A0A1E043   Q89777   A0A0A1E0Y6   A9JLL5   A0A385KLZ6   E0WMG4   A0A2X0RVA3   P0C9T9   E0WMG7   A0A2X0RTS3   P0C9T7   P0C9U4   A0A5B8XAP5   D4I5L8   P0C9T5   P0C9T2   A0A0C5BC47   P0C9T3   A0A0C5BCK1   A0A2Z5DEF5   A0A0A1DY94   A9JLL8   P0C9T4   P0C9U5   P0C9U1   A9JKV6   D4I5L5   A9JLL3   A0A0A1E0I1   Q89768   A9JKW0   D4I5L7   A9JLL7   A0A0A1E0L2   Q89925   A0A0N7CQW3   A0A3G1EUV7   A9JKW2   A0A0A1E2Z7   E0WMG6   A0A2X0S742   P0C9U3   P0C9U2   A0A0C5AZC1   P0C9U0   A0A0C5AZV5   A0A2Z5DFS5   A9JKW3   D4I5L9   A9JLM0   A0A0A1DXI4   Q89740   P0C9S6   P0C9U7   P0C9U8   A0A0C5B2F2   A0A0C5AYU4   A0A2Z5DGS0   P0C9U9   P0C9S5  
PDB
4ECO     E-value=7.35521,     Score=68

Ontologies

KEGG
vg:22220408     vg:22220414     vg:22220411     vg:22220410     vg:22220412     vg:22220413    

Subcellular Location

From MSLVP
Multi-Pass Membrane

Topology

Length:
516
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.0175
Exp number, first 60 AAs:
0.00248
Total prob of N-in:
0.00304
outside
1  -  516
 
 

Population Genetic Test Statistics

Pi
0.0726104
Theta
0.1219169
Tajima's D
-1.450881
CLR
0.000049
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
 AKO62707.1
China_AnhuiXCGQ_2018 Protein
 AYW33995.1
China_ASFV-SY18_2018 Protein
Protein
 CBH29126.1
AKO62707.1
Poland_Pol16_20186_o7_2016-2017 Protein
 AXZ95802.1
Poland_Pol16_20538_o9_2016-2017 Protein
 CAN10124.1
Poland_Pol16_20540_o10_2016-2017 Protein
 CAN10124.1
Poland_Pol16_29413_o23_2016-2017 Protein
 CAN10124.1
Poland_Pol17_03029_C201_2016-2017 Protein
 AXZ95990.1
Poland_Pol17_04461_C210_2016-2017 Protein
 AXZ96085.1
Poland_Pol17_05838_C220_2016-2017 Protein
 CAN10124.1
Poland_ASFV_POL_Podlaskie_2015 Protein
 CAN10124.1
Uganda_R8_2015 Protein
 AXB49255.1
Uganda_R7_2015 Protein
 AXB49429.1
Uganda_R25_2015 Protein
 AXB49601.1
Uganda_N10_2015 Protein
 AXB49773.1
Uganda_R35_2015 Protein
 AXB49945.1
Estonia_2014 Protein
 SPS73446.1
Italy_26544_OG10_2010 Protein
 AJZ77062.1
Italy_47_Ss_2008_2008 Protein
 AOO54349.1
Portugal_OURT_88.3_1988    
Spain_E75_1975 Protein
 CBH29126.1
Russia_Georgia_2007 Protein
 CBW46689.1
Kenya_Tk1_2005 Protein
 AJL34041.1
Kenya_Bus_2006 Protein
 AJL34206.1
Russia_Odintsovo_2014 Protein
 CAN10124.1
Portugal_L60_1960 Protein
 AIY22216.1
Portugal_NHV_1968    
Russia_Kashino_2013 Protein
 CAN10124.1
Benin_1997 Protein
Protein
 CAN10124.1
CAN10124.1
South_Africa_KNP_Pretorisuskop_1996 Protein
 CAN10124.1
South_Africa_MGR_Mkuzi_1979 Protein
 CAN10124.1
Malawi_Lil_1983 Protein
 CAN10124.1
Kenya_1950 Protein
 CAN10124.1
Namibia_Warthog_1980 Protein
 CAN10124.1
South_Africa_Warmbaths_1987 Protein
 CAN10124.1
Malawi_Tengani_1962 Protein
 CAN10124.1
China_HLJ_2018 Protein
 QBH90511.1
China_LN_2018 Protein
 QBH90696.1
China_wbBS01_2018 Protein
 QDL88054.1
Ukraine_Kyiv_2014 Protein
 QED21580.1
Belgium_Etalle_wb_2018 Protein
 QED90466.1
Lithuania_LT14_2014 Protein
 QEY87829.1
South_Africa_1985 Protein
 QGM12889.1
South_Africa_2_2008 Protein
 QGM12814.1
Zambia_LIV_1983 Protein
 QGM12692.1
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