ASFVdb The African Swine Fever Virus Database
Strain
Uganda_R7_2015 (Region: Uganda, Tororo district;  Strain: R7;  Date: 2015)
Gene
p505-2R
Description
Annotated in NCBI,  CBH29126.1
GenBank Accession
Full name
Protein MGF 505-2R       + More
Protein MGF 505-10R      
Protein MGF 505-5R      
Protein MGF 505-4R      
Protein MGF 505-7R      
Protein MGF 505-6R      
Protein MGF 505-1R      
Protein MGF 505-9R      
 

Sequence

CDS
ATGTTTTCCCTTCAAGACCTTTGCCGAAAGCATCTTTTTATTCTTCCCGATGTTTTTGGCGAGCATGTACTACAACAATTGGGGCTGTACTGGGAAAAACACGGCTCTCTTCAACGAATAGGGAACGATCACATACTCATACGGCGGGATCTCATCCTTTCTATCAACGAGGCCTTAAAAATAGCGGCAGAGGAAGGAAACAATGAAGTAGTAAAGCTCTTGTTACTGTGGAAGGGAAATCTTCATTATGCCATCATAGGAGCCTTGCAGGGTGACCAATATGACCTCATCCATACGTACGAAAACCAAATCGAAGACTATCATCATATCTTGCCATTGATTCAAGATGCGAAAACGTTTGAAAAATGCCACGCCTTGGAACGTTTTTGTGATGTTCCATGCCTACTAGAACATGCTACAAAACACAACATGCTCCCTATTCTCCAAAAATACCAAGAAGAGCTGTTTATAAGAGTGTATCTCCGCGAAACCCTATTTGAACTAGCATGCCTATGGCAGAGGTATGATATCCTTAAATGGATAGAGCAAACCATGCATGTTTACGACCTAAAGATTATGTTTAATATTGCCATCTCCAAGAGGGATCTAAGCATGTACTCTTTAGGATATATTCTCCTTTTTAATAGAGGGAACACCGATGTTGCGTTAGCAACGTTGCTAACGCAACATCTCGAGAAGACAGCGGCCAAGGGGCTCCTCCACTTTGTGCTAGAAACGTTAAAATACGGCGGTAACATAAACATCGTCCTCTCCCAAGCCGTAAAATACAATCATAGAAAACTTTTAGATTATTTTCTGCGTCAACTACCTCGTAAAAATATTGAAAAACTTTTGTTGCTGGCCGTACAGGAAAGGGCTTCTAAGAAAACATTGAACTTACTGTTGTCTTATTTAAACTACTCCGTGAAACGCATCAAAAAACTGCTGCGCTATGTGATAGAGCATGAGTCCACACTGGTGATAAGGATTTTATTAAAAAAAAGAATAAACCTAATAGACGCCGTGTTGGAAAAGACTGTAAGATATTTTTCTATGACTAAAGTGAGGACGATCATGGATGAGCTTTCGATTAATCCGGAAAAAGTCATTAAAATGGCCGTGCAGAAAATGAGAACGGATATCGTGATCCATACTTCTTATGTTTGGGAGGATGATCTAGAAAGACTTATTCGTCTTAAAAATATGCTATACACTATAAAGTATGAGCATGAAAAAAAAATGCTAATTAAAGTCATTCACGGCATATACAAAAACTTATACGGCGAAAAAGAAAAAGTCATGTTTAATTTGGCCAAGTTCTATGCTGCTCAAAACGCGGCCACCCAATTCAAAGACACTTGTAAAGACTGTTGCAAACTGGATGTGGCGCGGTTTAAACAACTAATTTTAGACTGTTTAGACATTATTACTAAAAAAACGTGCCTCAGTATCATGGAAATCTTAGAAAATCATATTATTTCGCTATTTGCTATGAAAATGATGACGGAGGATGAAAAAAACTTAGGTTTAGAAATATTATATAAAGTAATTAGTTACAAAATGATATCATATTAA
Protein
MFSLQDLCRKHLFILPDVFGEHVLQQLGLYWEKHGSLQRIGNDHILIRRDLILSINEALKIAAEEGNNEVVKLLLLWKGNLHYAIIGALQGDQYDLIHTYENQIEDYHHILPLIQDAKTFEKCHALERFCDVPCLLEHATKHNMLPILQKYQEELFIRVYLRETLFELACLWQRYDILKWIEQTMHVYDLKIMFNIAISKRDLSMYSLGYILLFNRGNTDVALATLLTQHLEKTAAKGLLHFVLETLKYGGNINIVLSQAVKYNHRKLLDYFLRQLPRKNIEKLLLLAVQERASKKTLNLLLSYLNYSVKRIKKLLRYVIEHESTLVIRILLKKRINLIDAVLEKTVRYFSMTKVRTIMDELSINPEKVIKMAVQKMRTDIVIHTSYVWEDDLERLIRLKNMLYTIKYEHEKKMLIKVIHGIYKNLYGEKEKVMFNLAKFYAAQNAATQFKDTCKDCCKLDVARFKQLILDCLDIITKKTCLSIMEILENHIISLFAMKMMTEDEKNLGLEILYKVISYKMISY

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Similarity
Belongs to the asfivirus MGF 505 family.
Keywords
Complete proteome   Reference proteome   ANK repeat   Repeat  
Feature
chain  Protein MGF 505-2R
EMBL
MH025916    MH025917    MH025918    MH025919    MH025920    AXB49255.1    + More
AXB49429.1    AXB49601.1    AXB49773.1    AXB49945.1    KM111295    AJL34206.1    AY261360    U03762    AY261361    AY261366    AM712239    CAN10124.1    KM262844    KM102979    KP055815    KX354450    AIY22216.1    AJZ77062.1    AKO62707.1    AOO54349.1    FR682468    CBW46689.1    MG939583    MG939587    MG939588    LS478113    AXZ95802.1    AXZ95990.1    AXZ96085.1    SPS73446.1    FN557520    CBH29126.1    U02468    U18466    AY261363    KM111294    AJL34041.1    CBH29133.1    AJL34047.1    AJL34212.1    AXB49261.1    AXB49435.1    AXB49607.1    AXB49778.1    AXB49951.1    AM712240    CAN10380.1    KM262845    AIY22382.1    AIY22223.1    AKO62714.1    AJZ77055.1    AOO54359.1    CAN10131.1    U03761    CBW46697.1    AXZ95809.1    AXZ95997.1    AXZ96092.1    SPS73454.1    AJL34209.1    AXB49258.1    AXB49432.1    AXB49604.1    AXB49775.1    AXB49948.1    CBW46693.1    SPS73450.1    AXZ95806.1    AXZ95994.1    AXZ96089.1    CAN10127.1    CBH29129.1    AIY22219.1    AJZ77066.1    AKO62710.1    AOO54354.1    CAN10376.1    AIY22378.1    AXZ95805.1    CBW46692.1    AXZ95993.1    AXZ96088.1    SPS73449.1    AJL34044.1    CAN10126.1    CBH29128.1    CAN10375.1    AIY22218.1    AIY22377.1    AJZ77065.1    AKO62709.1    AOO54353.1    AJL34043.1    AJL34208.1    AXB49257.1    AXB49431.1    AXB49603.1    AXB49947.1    CBW46695.1    SPS73452.1    CBH29130.1    CAN10377.1    AIY22220.1    AIY22379.1    AJZ77060.1    AKO62711.1    AOO54355.1    CAN10128.1    AOO54356.1    AKO62712.1    CAN10129.1    AIY22221.1    AJZ77061.1    CBH29131.1    CBW46694.1    AXZ95807.1    AXZ95995.1    AXZ96090.1    SPS73451.1    CAN10378.1    AIY22380.1    AJL34045.1    AJL34210.1    AXB49259.1    AXB49433.1    AXB49605.1    AXB49776.1    AXB49949.1    AJL34046.1    AJL34211.1    AXB49260.1    AXB49434.1    AXB49606.1    AXB49777.1    AXB49950.1    AJL34201.1    AJL34037.1    AXB49251.1    AXB49425.1    AXB49597.1    AXB49770.1    AXB49941.1    CAN10120.1    CBH29122.1    AIY22212.1    AKO62703.1    AJZ77058.1    AOO54340.1    CAN10130.1    CBH29132.1    CAN10379.1    AIY22222.1    AIY22381.1    AJZ77064.1    AKO62713.1    AOO54358.1   
Pfam
PF03158   DUF249
Interpro
IPR004858   MGF_505
IPR036770   Ankyrin_rpt-contain_sf
SUPFAM
SSF48403   SSF48403
Gene 3D
PDB
4ECO     E-value=7.35521,     Score=68

Ontologies

Subcellular Location

From MSLVP
Multi-Pass Membrane

Topology

Length:
524
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.03541
Exp number, first 60 AAs:
0.00464
Total prob of N-in:
0.00327
outside
1  -  524
 
 

Population Genetic Test Statistics

Pi
0.071056
Theta
0.1183583
Tajima's D
-1.4489045
CLR
0.066748
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
AKO62707.1
China_AnhuiXCGQ_2018 Protein
AYW33995.1
China_ASFV-SY18_2018 Protein
Protein
CBH29126.1
AKO62707.1
Poland_Pol16_20186_o7_2016-2017 Protein
AXZ95802.1
Poland_Pol16_20538_o9_2016-2017 Protein
CAN10124.1
Poland_Pol16_20540_o10_2016-2017 Protein
CAN10124.1
Poland_Pol16_29413_o23_2016-2017 Protein
CAN10124.1
Poland_Pol17_03029_C201_2016-2017 Protein
AXZ95990.1
Poland_Pol17_04461_C210_2016-2017 Protein
AXZ96085.1
Poland_Pol17_05838_C220_2016-2017 Protein
CAN10124.1
Poland_ASFV_POL_Podlaskie_2015 Protein
CAN10124.1
Uganda_R8_2015 Protein
AXB49255.1
Uganda_R7_2015 Protein
AXB49429.1
Uganda_R25_2015 Protein
AXB49601.1
Uganda_N10_2015 Protein
AXB49773.1
Uganda_R35_2015 Protein
AXB49945.1
Estonia_2014 Protein
SPS73446.1
Italy_26544_OG10_2010 Protein
AJZ77062.1
Italy_47_Ss_2008_2008 Protein
AOO54349.1
Portugal_OURT_88.3_1988    
Spain_E75_1975 Protein
CBH29126.1
Russia_Georgia_2007 Protein
CBW46689.1
Kenya_Tk1_2005 Protein
AJL34041.1
Kenya_Bus_2006 Protein
AJL34206.1
Russia_Odintsovo_2014 Protein
CAN10124.1
Portugal_L60_1960 Protein
AIY22216.1
Portugal_NHV_1968    
Russia_Kashino_2013 Protein
CAN10124.1
Benin_1997 Protein
Protein
CAN10124.1
CAN10124.1
South_Africa_KNP_Pretorisuskop_1996 Protein
CAN10124.1
South_Africa_MGR_Mkuzi_1979 Protein
CAN10124.1
Malawi_Lil_1983 Protein
CAN10124.1
Kenya_1950 Protein
CAN10124.1
Namibia_Warthog_1980 Protein
CAN10124.1
South_Africa_Warmbaths_1987 Protein
CAN10124.1
Malawi_Tengani_1962 Protein
CAN10124.1
China_HLJ_2018 Protein
QBH90511.1
China_LN_2018 Protein
QBH90696.1
China_wbBS01_2018 Protein
QDL88054.1
Ukraine_Kyiv_2014 Protein
QED21580.1
Belgium_Etalle_wb_2018 Protein
QED90466.1
Lithuania_LT14_2014 Protein
QEY87829.1
South_Africa_1985 Protein
QGM12889.1
South_Africa_2_2008 Protein
QGM12814.1
Zambia_LIV_1983 Protein
QGM12692.1
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