ASFVdb The African Swine Fever Virus Database
Strain
Spain_E75_1975 (Region: Spain;  Strain: E75;  Date: 1975)
Gene
hypothetical protein ASFV_Kyiv_2016_131_00059
Description
With frameshift mutation but translatable,  hypothetical protein
Location
FN557520.1(-):44717-46522
GenBank Accession
QED21595.1
Full name
Probable helicase A859L       + More
Helicase ATP-binding domain-containing protein      
 

Sequence

CDS
ATGACCACCAATCCTGTCTTTATTGCAAAACGGATACGGGAGGCCCCTTCTCTTCTTGTGATTGCCACCTACCAATCCTCCACGCTACTGGTGGATGATTTCGATCTTATTATTAGCGATGAATGTCACCGGATTTGCGGTGAATGGGAGACACGGCCCTTTACCCATGTGTTGCTCAACTTTAAAAAAGGGCACCGACTTTTTTTAACGGCAACGCCCAGGTACGACACCCCGCTTTCCATGAAAAATCGTGAACTTTTTGGCGGCGTTGCCTTTCGCTACTATCTGCGAGAAGGCATAGAGGCCGGCTATGTAAATGATTTTGAATTACAAATGGTAGCCGCGCCCAAATTGGCTCACCAACCGAGTAACAGAGAGGAGACCACGAAACAGATCATAGTAAAGCAAATTATAATGGCCTTAGCCTATTTAAAAACCAATATACCGGCTCCTAAAATGCTGGTATTCACCCGTGATATTAAACAGGCCAGGGAGCTATACGCGGAGTTGGTAGACCAAGGGGTCTATGCCCTGATAGCTCACTCAACCCTGCCGCGACAGGTTATCCTCAAAACATTTACAGAATTTTGTTCCTCAAAGGAACCCGTTATTTTATTAAACTGTCGACTCTTTCAAGAGGGCGTAGAGGTTCCGGAACTAAACGCGGTATTTTTTGCAGCGCCGCGTCATAGTCCTAGAGACATTATTCAAAGCATATGCAGACCGCTGAACAAGCAGGTTCAAAAGCCTCACGCAACCATTTTTCTACCTTTAGAAGTAAACACAGAAAACGTATGCCTAGACAGGTTTTCTAGTATTATCCCTTTTGCAGACGCCTTGGCGTCTGAAGATCCACGCTTTTACGAGCATCTTTTAAACCCTTCAGAGGTTGCCTATCCGATAAACTGGATCGGGGCCCACGGATCGGTGTCAGAATTGTTGCAATTGGCACGTCACGCCATACGCTATGGTACGCAGGGCAAAATAGACCGCCTTACCCGCAGCGAGAGACTTCCTTGGAAGGCCGCCTTTGCAGAACTCAAACGTACGGTTGAAATATGTTGCAGATATCCTAAAATCAACGACGGCTTTCACTTTGGAGGCGCCACGCTGCGGTTCGACACATGGTATAAATGGGTCATTAAATCCTATTTGCAGTACAAAAACAAGGAACCGTCTTCTTTAGAGCCTTACCAGGTGTCGGACCTGGAGTCCTTGCAAGATTGGACAACCCGTGGTGTTGGCGGGCCTTATCCCTGGGAAGAAAGCATGGCATTCTTGGAAACTTGGCTTGCCCAAAATAAAGGAGAGCTTGTTGCCATTGATATTCATCAGGGTGGATGGATAGGATTGGACGCGACGCCCATGGAAAGGCTGTCGGGCGTCCTAACCACTGTTTCGCAACGCGATGGCCGAAGCTATGGAAAAAATAAAAAGCTTCGACCTAAAAAGGGGTTTATGATCCCACCCCAGCAGGCCGAAGATCTTGACCGTATTTTTGGAAAGCACAATCTTAAGTGGAGAAAGGACAGGGTTAATGGCTTTTTAAAGGAAGATGAACACGGAAATTATACAGGCGAGCCTACCTGTATTCAAGAAGCCTATCGGACCTTTAAAGAATATGTAAAAACAAATCCCGAATATATCGAAAAATACTGGCCTGGATATGCCAAAGGCAAGCATAAACACCAAGAATTACCGCACATATGGGAAAGCGGCCTGGCTCCTCCCCGCTATAAGGCATTTAAAGATGGTAATAAACAGCTTATCCAAAGAAGTCCGAAAAAAAAGGACATTAAAAATTAA
Protein
MTTNPVFIAKRIREAPSLLVIATYQSSTLLVDDFDLIISDECHRICGEWETRPFTHVLLNFKKGHRLFLTATPRYDTPLSMKNRELFGGVAFRYYLREGIEAGYVNDFELQMVAAPKLAHQPSNREETTKQIIVKQIIMALAYLKTNIPAPKMLVFTRDIKQARELYAELVDQGVYALIAHSTLPRQVILKTFTEFCSSKEPVILLNCRLFQEGVEVPELNAVFFAAPRHSPRDIIQSICRPLNKQVQKPHATIFLPLEVNTENVCLDRFSSIIPFADALASEDPRFYEHLLNPSEVAYPINWIGAHGSVSELLQLARHAIRYGTQGKIDRLTRSERLPWKAAFAELKRTVEICCRYPKINDGFHFGGATLRFDTWYKWVIKSYLQYKNKEPSSLEPYQVSDLESLQDWTTRGVGGPYPWEESMAFLETWLAQNKGELVAIDIHQGGWIGLDATPMERLSGVLTTVSQRDGRSYGKNKKLRPKKGFMIPPQQAEDLDRIFGKHNLKWRKDRVNGFLKEDEHGNYTGEPTCIQEAYRTFKEYVKTNPEYIEKYWPGYAKGKHKHQELPHIWESGLAPPRYKAFKDGNKQLIQRSPKKKDIKN

Summary

Similarity
Belongs to the asfivirus helicase A859L family.
Keywords
ATP-binding   Complete proteome   Helicase   Hydrolase   Nucleotide-binding   Reference proteome  
Feature
chain  Probable helicase A859L
Uniprot
E0WMH8   A0A385KMI0   P0C8H2   P0C8H3   A0A2X0SDV7   A9JKX8   + More
D4I5M8   A9JLN7   A0A0A1E304   Q65143   A0A5B8XA67   P0C8H1   A0A0C5AW97   P0C8H0   A0A0C5AWM3   A0A2Z5DFT6   G0UY07   W6KWA5   A0A3P3ZDB3   A0A088RX71   A0A1E1J2G5   A4HIX1   E9B1F5   A0A3Q8IF99   A0A5K1V5S9   A4I6A0   A0A504WY43   E9BMD0   A0A504X3C3   S9VVA9   K2N7A9   S9VG44   A0A0M9FQI1   A0A2V2V286   Q4Q6Q7   A0A1X0P8K5   A0A2V2UZK3   V5B0I9   Q4CVA8   A0A2V2W8E1   A0A422QAD5   A0A3R7KPC7   Q4D326   A0A3L6KYF2   D0A541   A0A1G4I059   Q389B2   A0A061J8L4   A0A0N1I3J1   S9UAM1   S9U4B4   W6LCV2   G0U3Z4   A0A2K4YAM4   A0A4V2RKV7   A0A552ZIJ3   A0A100ZNW4   A0A260MWW2   A2BTY5   A0A150A2K1   A0A3D9TS91   X7YQE2   A0A498QR07   A0A1A0V3S0   A0A1P8XF02   A0A1A2BD48   A0A0U0W7V0   I0WG10   A0A523YUR4   A0A259XM75   A0A1S1M1F6   A0A0A2ADH2   A0A498PJD7   A0A1A3BPM7   A0A481Z4U3   A0A1U9PGQ8   A0A424HZD6   A0A0D6J306   A0A1X2LFP7   A0A557XC56   A0A260MYB1   A0A238VZB5   A0A4Z0NA41   A0A1X0BPD4   A0A1A3KSX4   A0A1U9PKG7   A0A1T4J0N7   A0A1A3GDI7   A0A1Z8SVB0   A0A424RA97   A0A1A1WE99   A0A2S8KKE5   A0A022LAC5   A0A1T4J0D6   J4JUX8   A0A260PYZ5   A0A0F2P7N8  
Pubmed
21470447    18198370    25406173    26618713    11831707    25645905    + More
22331916    24516393    25707621    17572675    22038252    30409989    22038251    23560078    23035642    29708484    16020728    24482508    16020725    30355302    20404998    16020726    26317207    26203337    18159947    26804932    22689233    25977791    30837339    28713657    23661480    21952541   
EMBL
FR682468    CBW46706.1    MG939583    MG939587    MG939588    AXZ95816.1    + More
AXZ96004.1    AXZ96099.1    AY261363    AY261366    LS478113    SPS73463.1    AM712239    CAN10139.1    FN557520    CBH29141.1    AM712240    CAN10388.1    KM262844    KM262845    KM102979    KP055815    KX354450    AIY22231.1    AIY22390.1    AJZ77050.1    AKO62722.1    AOO54370.1    U18466    MN194591    QED21595.1    AY261361    KM111294    AJL34054.1    AY261360    KM111295    AJL34219.1    MH025916    MH025917    MH025918    MH025919    MH025920    AXB49269.1    AXB49443.1    AXB49615.1    AXB49786.1    AXB49959.1    HE575323    CCC94274.1    HF955125    CCW65814.1    LS997630    SYZ68202.1    CP009400    AIO00599.1    CALQ01001382    CCM17777.1    FR799006    CAM42427.1    FR799583    CBZ29061.1    CP029530    AYU81185.1    UINB01000031    SUZ44206.1    FR796463    CAM70323.1    RHLD01000005    TPP41621.1    FR799618    CBZ36408.1    RHLC01000006    TPP42773.1    ATMG01010879    EPY27205.1    AHKC01011967    EKF30546.1    ATMG01003987    EPY39939.1    LGTL01000032    KPA74015.1    PRFC01000359    PWU90645.1    FR796427    CAJ08152.1    NBCO01000003    ORC92770.1    PRFA01000058    PWU89540.1    AYLP01000041    ESS66650.1    AAHK01001763    EAN84209.1    PRFC01000144    PWV04781.1    MKKU01000023    RNF26928.1    MKGL01000442    RNE98701.1    AAHK01001120    EAN86926.1    QSBY01000010    RHW69379.1    FN554973    CBH16385.1    CZPT02000209    SCU65038.1    CM000208    EAN78608.1    AUPL01000464    ESL11778.1    LJSK01000007    KPI90361.1    ATMH01009351    ATMH01006855    ATMH01006372    ATMH01002372    ATMH01000607    EPY19648.1    EPY25075.1    EPY25998.1    EPY33256.1    EPY36395.1    ATMH01007630    EPY23604.1    HF955212    CCW71644.1    HE573026    CCC52156.1    FXEG02000002    SOX53839.1    SLVY01000006    TCN53370.1    VKAA01000022    TRW79285.1    LQIL01000001    KUH91864.1    NOZH01000002    OZE43162.1    CP000552    ABM71246.1    LTCZ01000066    KXX60900.1    QTTW01000006    REF15038.1    JANZ01000008    EUA08625.1    UPHU01000001    VBA48749.1    LZSW01000010    OBB77877.1    CP019420    AQA04894.1    LZIF01000074    OBF65975.1    CSTD01000002    CPR10900.1    AJJH01000157    EID75326.1    SOIG01000498    TET95271.1    NOYA01000035    OZC55568.1    MLIS01000001    OHU77030.1    JNAM01000002    KGF98901.1    UPHL01000125    VAZ85581.1    LZKP01000161    OBI75882.1    MK500433    QBK89660.1    CP019882    AQT80276.1    NHBZ02000014    RPF84212.1    LN831039    CKI51574.1    NCXO01000032    OSC32810.1    VMQU01000158    TVS83096.1    OZE43160.1    FZNT01000002    SNR39223.1    SRLQ01000003    TGD89224.1    MVHN01000025    ORA44543.1    LZLK01000077    OBJ87468.1    AQT81508.1    FTQU01000001    SIU03354.1    LZLB01000010    OBJ34102.1    NHCQ01000092    OUU26378.1    NHJG02000010    RPG88344.1    LZHT01000041    OBF05342.1    PUTX01001013    PQP39737.1    AOSR01000043    EYT60945.1    SIU03352.1    AFVW02000004    EJO88062.1    NOZM01000005    OZE68040.1    LADQ01000260    KJS08562.1   
Proteomes
UP000141072    UP000000859    UP000000858    UP000130745    UP000101090    UP000108903    + More
UP000110401    UP000117635    UP000142390    UP000241813    UP000266411    UP000000624    UP000321214    UP000000860    UP000105860    UP000000861    UP000101566    UP000007258    UP000007259    UP000274082    UP000255414    UP000008153    UP000318821    UP000008980    UP000318447    UP000000542    UP000002296    UP000002316    UP000008524    UP000015354    UP000236318    UP000295305    UP000320222    UP000054385    UP000216746    UP000001589    UP000075580    UP000257142    UP000268285    UP000092013    UP000188050    UP000091887    UP000198875    UP000006447    UP000216115    UP000179441    UP000030445    UP000279331    UP000092151    UP000189653    UP000196051    UP000062612    UP000193577    UP000320513    UP000198384    UP000297600    UP000192556    UP000093974    UP000190894    UP000093933    UP000196085    UP000196760    UP000092144    UP000239797    UP000019757    UP000006455    UP000216557    UP000050680   
PRIDE
P0C8H2    P0C8H3    Q65143    P0C8H1    P0C8H0   
Pfam
PF00271   Helicase_C
PF04851   ResIII
PF10544   T5orf172
PF03457   HA
PF13156   Mrr_cat_2
PF18135   Type_ISP_C
PF02384   N6_Mtase
Interpro
IPR018306   Phage_T5_Orf172_DNA-bd
IPR027417   P-loop_NTPase
IPR001650   Helicase_C
IPR014001   Helicase_ATP-bd
IPR006935   Helicase/UvrB_N
IPR036770   Ankyrin_rpt-contain_sf
IPR020683   Ankyrin_rpt-contain_dom
IPR002110   Ankyrin_rpt
IPR005114   Helicase_assoc
IPR011335   Restrct_endonuc-II-like
IPR039442   Mrr-like_dom
IPR002052   DNA_methylase_N6_adenine_CS
IPR041635   Type_ISP_LLaBIII_C
IPR029063   SAM-dependent_MTases
IPR003356   DNA_methylase_A-5
SUPFAM
SSF52540   SSF52540
SSF48403   SSF48403
SSF52980   SSF52980
SSF53335   SSF53335
Gene 3D
1.25.40.20    
CDD
cd00079  HELICc
ProteinModelPortal
E0WMH8   A0A385KMI0   P0C8H2   P0C8H3   A0A2X0SDV7   A9JKX8   + More
D4I5M8   A9JLN7   A0A0A1E304   Q65143   A0A5B8XA67   P0C8H1   A0A0C5AW97   P0C8H0   A0A0C5AWM3   A0A2Z5DFT6   G0UY07   W6KWA5   A0A3P3ZDB3   A0A088RX71   A0A1E1J2G5   A4HIX1   E9B1F5   A0A3Q8IF99   A0A5K1V5S9   A4I6A0   A0A504WY43   E9BMD0   A0A504X3C3   S9VVA9   K2N7A9   S9VG44   A0A0M9FQI1   A0A2V2V286   Q4Q6Q7   A0A1X0P8K5   A0A2V2UZK3   V5B0I9   Q4CVA8   A0A2V2W8E1   A0A422QAD5   A0A3R7KPC7   Q4D326   A0A3L6KYF2   D0A541   A0A1G4I059   Q389B2   A0A061J8L4   A0A0N1I3J1   S9UAM1   S9U4B4   W6LCV2   G0U3Z4   A0A2K4YAM4   A0A4V2RKV7   A0A552ZIJ3   A0A100ZNW4   A0A260MWW2   A2BTY5   A0A150A2K1   A0A3D9TS91   X7YQE2   A0A498QR07   A0A1A0V3S0   A0A1P8XF02   A0A1A2BD48   A0A0U0W7V0   I0WG10   A0A523YUR4   A0A259XM75   A0A1S1M1F6   A0A0A2ADH2   A0A498PJD7   A0A1A3BPM7   A0A481Z4U3   A0A1U9PGQ8   A0A424HZD6   A0A0D6J306   A0A1X2LFP7   A0A557XC56   A0A260MYB1   A0A238VZB5   A0A4Z0NA41   A0A1X0BPD4   A0A1A3KSX4   A0A1U9PKG7   A0A1T4J0N7   A0A1A3GDI7   A0A1Z8SVB0   A0A424RA97   A0A1A1WE99   A0A2S8KKE5   A0A022LAC5   A0A1T4J0D6   J4JUX8   A0A260PYZ5   A0A0F2P7N8  
PDB
5FFJ     E-value=9.67346e-18,     Score=225

Ontologies

KEGG
vg:22220422    
GO
GO:0003677  F:DNA binding
 GO:0005524  F:ATP binding
 GO:0016787  F:hydrolase activity
 GO:0004386  F:helicase activity
 GO:0016021  C:integral component of membrane
 GO:0043138  F:3'-5' DNA helicase activity
 GO:0006367  P:transcription initiation from RNA polymerase II promoter
 GO:0006366  P:transcription by RNA polymerase II
 GO:0033683  P:nucleotide-excision repair, DNA incision
 GO:0000112  C:nucleotide-excision repair factor 3 complex
 GO:0020023  C:kinetoplast
 GO:0009411  P:response to UV
 GO:0004003  F:ATP-dependent DNA helicase activity
 GO:0005675  C:transcription factor TFIIH holo complex
 GO:0006468  P:protein phosphorylation
 GO:0097550  C:transcriptional preinitiation complex
 GO:0008134  F:transcription factor binding
 GO:0003678  F:DNA helicase activity
 GO:0004519  F:endonuclease activity
 GO:0008168  F:methyltransferase activity
 GO:0032259  P:methylation
 GO:0006306  P:DNA methylation
 GO:0008170  F:N-methyltransferase activity

Subcellular Location

From MSLVP
Nucleus

Topology

Length:
601
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.0381700000000001
Exp number, first 60 AAs:
0.01512
Total prob of N-in:
0.00318
outside
1  -  601
 
 

Population Genetic Test Statistics

Pi
0.0280215
Theta
0.0352706
Tajima's D
-0.6229662
CLR
0
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
Protein
 QED21595.1
AKO62722.1
China_AnhuiXCGQ_2018 Protein
Protein
 QED21595.1
AYW34012.1
China_ASFV-SY18_2018 Protein
 AKO62722.1
Poland_Pol16_20186_o7_2016-2017 Protein
Protein
 QED21595.1
AXZ95816.1
Poland_Pol16_20538_o9_2016-2017 Protein
Protein
 CAN10139.1
QED21595.1
Poland_Pol16_20540_o10_2016-2017 Protein
Protein
 CAN10139.1
QED21595.1
Poland_Pol16_29413_o23_2016-2017 Protein
Protein
 CAN10139.1
QED21595.1
Poland_Pol17_03029_C201_2016-2017 Protein
Protein
 QED21595.1
AXZ96004.1
Poland_Pol17_04461_C210_2016-2017 Protein
Protein
 QED21595.1
AXZ96099.1
Poland_Pol17_05838_C220_2016-2017 Protein
Protein
 CAN10139.1
QED21595.1
Poland_ASFV_POL_Podlaskie_2015 Protein
Protein
 CAN10139.1
QED21595.1
Uganda_R8_2015 Protein
Protein
 QED21595.1
AXB49269.1
Uganda_R7_2015 Protein
Protein
 QED21595.1
AXB49443.1
Uganda_R25_2015 Protein
Protein
 QED21595.1
AXB49615.1
Uganda_N10_2015 Protein
Protein
 QED21595.1
AXB49786.1
Uganda_R35_2015 Protein
Protein
 QED21595.1
AXB49959.1
Estonia_2014 Protein
Protein
 QED21595.1
SPS73463.1
Italy_26544_OG10_2010 Protein
Protein
 QED21595.1
AJZ77050.1
Italy_47_Ss_2008_2008 Protein
Protein
 QED21595.1
AOO54370.1
Portugal_OURT_88.3_1988 Protein
Protein
 QED21595.1
CAN10388.1
Spain_E75_1975 Protein
Protein
 QED21595.1
CBH29141.1
Russia_Georgia_2007 Protein
Protein
 QED21595.1
CBW46706.1
Kenya_Tk1_2005 Protein
Protein
 QED21595.1
AJL34054.1
Kenya_Bus_2006 Protein
Protein
 QED21595.1
AJL34219.1
Russia_Odintsovo_2014 Protein
Protein
 CAN10139.1
QED21595.1
Portugal_L60_1960 Protein
Protein
 QED21595.1
AIY22231.1
Portugal_NHV_1968 Protein
Protein
 QED21595.1
AIY22390.1
Russia_Kashino_2013 Protein
Protein
 CAN10139.1
QED21595.1
Benin_1997 Protein
Protein
Protein
 CAN10139.1
QED21595.1
CAN10139.1
South_Africa_KNP_Pretorisuskop_1996 Protein
Protein
 CAN10139.1
QED21595.1
South_Africa_MGR_Mkuzi_1979 Protein
Protein
 CAN10139.1
QED21595.1
Malawi_Lil_1983 Protein
 CAN10139.1
Kenya_1950 Protein
Protein
 CAN10139.1
QED21595.1
Namibia_Warthog_1980 Protein
Protein
 CAN10139.1
QED21595.1
South_Africa_Warmbaths_1987 Protein
Protein
 CAN10139.1
QED21595.1
Malawi_Tengani_1962 Protein
Protein
 CAN10139.1
QED21595.1
China_HLJ_2018 Protein
Protein
 QED21595.1
QBH90528.1
China_LN_2018 Protein
Protein
 QED21595.1
QBH90713.1
China_wbBS01_2018 Protein
Protein
 QED21595.1
QDL88071.1
Ukraine_Kyiv_2014 Protein
 QED21596.1
Belgium_Etalle_wb_2018 Protein
Protein
 QED21595.1
QED90483.1
Lithuania_LT14_2014 Protein
Protein
 QED21595.1
QEY87846.1
South_Africa_1985 Protein
 CAN10139.1
South_Africa_2_2008 Protein
 CAN10139.1
Zambia_LIV_1983 Protein
 CAN10139.1
Copyright@ 2018-2023    Any Comments and suggestions mail to:  zhuzl@cqu.edu.cn, mg@cau.edu.cn   渝ICP备19006517号

渝公网安备 50010602502065号
In processing...
Login to ASFVdb
Email
Password
Please go to Regist if without an account.
If you have forgotten your password, you can once again Regist an account with a registed or new email.
Cancel Go
Change my password
Enter new password
Reenter new password
Cancel Go
Regist an account of ASFVdb
It is required that you provide your institutional e-mail address (with edu or org in the domain) as confirmation of your affiliation.
Enter email
Reenter email
First Name
Last Name
Institution
You can directly go to if with an account.
Cancel Regist
Registraion Success
Your password has been sent to your email.
Please check it and login later.
Welcome to use ASFVdb.
OK