Strain

China_ASFV-SY18_2018 (Region: China; Strain: ASFV-SY18; Date: 2018)

Gene

ASFV_G_ACD_01760

Description

Annoated by sequence mapping, ASFV_G_ACD_01760

Location

MH766894.1(-):174930-175013

GenBank Accession

CBW46809.1

Full name

Membrane protein I177L

CDS

ATGTATGAAATTATTTTGGCGATTATTATCATACTTTTAACAATTATTATTTTTATTTTTATAAAACACCCTTTAAATGTATAA

Protein

MYEIILAIIIILLTIIIFIFIKHPLNV

Similarity

Belongs to the asfivirus I177L family.

Keywords

Complete proteome Host membrane Late protein Membrane Transmembrane Transmembrane helix Glycoprotein

Feature

chain Membrane protein I177L

Uniprot

E0WM93 P0CA81 A0A0C5BCW3 A0A2Z5DFW7 A0A0C5AWG3 P0CA80 + More
E0VHR1 A0A1G3AMR6 A0A151E4Z8 A0A222P281 A0A2E6KIV6

Pubmed

21470447 25645905 20566863 27774985 29337314

EMBL

FR682468 CBW46809.1 AY261361 KM111295 MH025916 MH025917 + More
MH025918 MH025920 AJL34318.1 AXB49370.1 AXB49544.1 AXB49716.1 AXB50060.1 MH025919 AXB49887.1 KM111294 AJL34154.1 AY261360 DS235171 EEB12947.1 MHYP01000172 OHB84287.1 LSSE01000006 KYK23695.1 CP016397 ASQ45931.1 PBJG01000023 MBK66425.1

Proteomes

UP000141072 UP000000860 UP000101566 UP000105860 UP000000861 UP000009046 + More
UP000201728

Pfam

PF06585   JHBP
PF13181   TPR_8
PF00515   TPR_1
PF01554   MatE
PF03706   LPG_synthase_TM
PF02646   RmuC

Interpro

IPR010562   Haemolymph_juvenile_hormone-bd
IPR038606   To_sf
IPR013026   TPR-contain_dom
IPR001440   TPR_1
IPR011990   TPR-like_helical_dom_sf
IPR019734   TPR_repeat
IPR002528   MATE_fam
IPR022791   L-PG_synthase/AglD
IPR003798   DNA_recombination_RmuC

SUPFAM

SSF48452 SSF48452

Gene 3D

3.15.10.30 1.25.40.10

ProteinModelPortal

E0WM93 P0CA81 A0A0C5BCW3 A0A2Z5DFW7 A0A0C5AWG3 P0CA80 + More
E0VHR1 A0A1G3AMR6 A0A151E4Z8 A0A222P281 A0A2E6KIV6

PANTHER

PTHR30563

PDB

6OSX E-value=0.284755, Score=74

Ontologies

GO

GO:0016021  C:integral component of membrane
GO:0033644  C:host cell membrane
GO:0015238  F:drug transmembrane transporter activity
GO:0015297  F:antiporter activity

Subcellular Location

From MSLVP

Single-Pass Membrane

From Uniprot

Host membrane

Topology

Length:

27

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

19.31437

Exp number, first 60 AAs:

19.31437

Total prob of N-in:

0.19857

POSSIBLE N-term signal

sequence

outside

1 - 3

TMhelix

4 - 21

inside

22 - 27

Population Genetic Test Statistics

Pi

0.0398035

Theta

0.0402427

Tajima's D

-0.0383562

CLR

1.631613

Interpretation

Possibly Balancing Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein	AKO62823.1
China_AnhuiXCGQ_2018	Protein Protein	CAN10241.1 AYW34113.1
China_ASFV-SY18_2018	Protein Protein	CBW46808.1 CBW46809.1
Poland_Pol16_20186_o7_2016-2017	Protein Protein	CAN10241.1 AXZ95913.1
Poland_Pol16_20538_o9_2016-2017
Poland_Pol16_20540_o10_2016-2017	Protein	CAN10241.1
Poland_Pol16_29413_o23_2016-2017	Protein	CAN10241.1
Poland_Pol17_03029_C201_2016-2017	Protein	CAN10241.1
Poland_Pol17_04461_C210_2016-2017	Protein Protein	CAN10241.1 AXZ96196.1
Poland_Pol17_05838_C220_2016-2017	Protein	CAN10241.1
Poland_ASFV_POL_Podlaskie_2015	Protein	CAN10241.1
Uganda_R8_2015
Uganda_R7_2015
Uganda_R25_2015
Uganda_N10_2015
Uganda_R35_2015
Estonia_2014	Protein	SPS73565.1
Italy_26544_OG10_2010	Protein	AJZ77141.1
Italy_47_Ss_2008_2008	Protein	AOO54514.1
Portugal_OURT_88.3_1988	Protein	CAN10491.1
Spain_E75_1975	Protein	CBH29242.1
Russia_Georgia_2007	Protein Protein	CBW46808.1 CBW46809.1
Kenya_Tk1_2005	Protein	AJL34154.1
Kenya_Bus_2006
Russia_Odintsovo_2014
Portugal_L60_1960	Protein	AIY22333.1
Portugal_NHV_1968	Protein	AIY22491.1
Russia_Kashino_2013	Protein	CAN10241.1
Benin_1997	Protein Protein	CAN10241.1 CAN10241.1
South_Africa_KNP_Pretorisuskop_1996	Protein	CAN10241.1
South_Africa_MGR_Mkuzi_1979	Protein	CAN10241.1
Malawi_Lil_1983	Protein	CAN10241.1
Kenya_1950	Protein	CAN10241.1
Namibia_Warthog_1980	Protein	CAN10241.1
South_Africa_Warmbaths_1987	Protein	CAN10241.1
Malawi_Tengani_1962	Protein	CAN10241.1
China_HLJ_2018	Protein Protein	QBH90630.1 QBH90631.1
China_LN_2018	Protein Protein	QBH90815.1 QBH90816.1
China_wbBS01_2018	Protein Protein	QDL88173.1 QDL88174.1
Ukraine_Kyiv_2014	Protein	QED21758.1
Belgium_Etalle_wb_2018	Protein Protein	CAN10241.1 QED90585.1
Lithuania_LT14_2014	Protein	QEY87948.1
South_Africa_1985
South_Africa_2_2008
Zambia_LIV_1983

Sequence