Strain

China_ASFV-SY18_2018 (Region: China; Strain: ASFV-SY18; Date: 2018)

Gene

pBA71-B602L

Description

With frameshift mutation but translatable, contains highly variable tandem repeats

Location

MH766894.1(-):100689-102281

GenBank Accession

AKO62761.1

Full name

Protein B602L

CDS

ATGGCAGAATTTAATATTGATGAGCTTCTCAAAAACGTATTGGAGGATCCCTCTACTGAAATATCCGAAGAAACGCTTAAACAGCTTTACCAAAGGACGAACCCTTACAAACAGTTCAAAAATGATAGCAGGGTGGCCTTTTGCTCTTTTACAAATTTGCGGGAGCAGTATATTCGACGTCTTATAATGACTAGCTTTATTGGATATGTCTTCAAAGCTCTGCAGGAATGGATGCCTTCCTATTCAAAACCTACCCACACGACCAAAACTCTTCTCAGTGAGCTAATAACGTTAGTTGATACTTTGAAACAGGAAACTAATGATGTTCCCTCTGAATCGGTAGTAAATACAATTTTATCTATAGCAGATAGCTGCAAAACCCAGACGCAGAAAAGCAAGGAAGCTAAAACAACGATCGATAGCTTTTTACGAGAACATTTTGTGTTTGATCCTAATCTTCATGCTCAAAGTGCGTATACTTGTGCAGATACCAATGTAGACACTTGTGCAAGCATGTGTGCAGATACCAATGTAGACACCTGTGCAAGCATGTGTGCAGATACCAATGTAGATACCTGTGCAAGCACTTGTACAAGCACAGAATACACCGATTTAGCAGATCCTGAGCGCATCCCTTTACACATCATGCAAAAAACATTAAATGTGCCTAATGAGCTTCAGGCCGATATTGATGCAATCACCCAAACCCCACAGGGCTATAGGGCAGCAGCCCACATATTACAAAATATAGAACTTCACCAAAGCATTAAACATATGCTTGAAAATCCGAGGGCGTTTAAACCCATTCTCTTTAACACAAAAATTACTAGATATCTTTCGCAGCATATTCCACCTCAGGATACTTTTTATAAGTGGAATTATTACATTGAGGATAATTACGAAGAGTTGCGGGCCGCTACGGAAAGCATCTACCCAGAAAAACCCGACCTAGAGTTTGCCTTCATTATTTATGATGTGGTGGATAGCAGCAACCAACAAAAGGTTGATGAATTTTATTATAAATATAAAGACCAGATTTTCTCAGAGGTTTCATCCATTCAATTAGGCAACTGGACACTCCTGGGAAGCTTTAAGGCCAACAGAGAGCGCTACAATTATTTTAATCAAAATAATGAAATAATAAAACGGATTTTGGACCGTCATGAGGAAGACCTAAAGATAGGAAAAGAGATTTTACGAAATACTATTTACCACAAAAAAGCAAAAAATATACAAGAAACTGGCCCGGATGCTCCGGGGCTCTCCATCTATAATTCAACCTTTCACACGGATAGCGGGATTAAGGGACTGCTTTCCTTTAAGGAGCTAAAAAACCTAGAAAAAGCATCTGGAAATATCAAAAAAGCTCGAGAGTATGATTTTATAGACGACTGCGAAGAAAAAATTAAGCAACTGCTTAGTAAAGAAAATTTAACCCCCGATGAAGAAAGCGAGCTGATAAAAACAAAAAAACAGTTAGATAATGCGCTTGAAATGCTCAATGTGCCTGATGATACGATACGGGTAGATATGTGGGTCAACAATAATAATAAACTCGAAAAAGAAATTTTATATACAAAAGCAGAATTGTAA

Protein

MAEFNIDELLKNVLEDPSTEISEETLKQLYQRTNPYKQFKNDSRVAFCSFTNLREQYIRRLIMTSFIGYVFKALQEWMPSYSKPTHTTKTLLSELITLVDTLKQETNDVPSESVVNTILSIADSCKTQTQKSKEAKTTIDSFLREHFVFDPNLHAQSAYTCADTNVDTCASMCADTNVDTCASMCADTNVDTCASTCTSTEYTDLADPERIPLHIMQKTLNVPNELQADIDAITQTPQGYRAAAHILQNIELHQSIKHMLENPRAFKPILFNTKITRYLSQHIPPQDTFYKWNYYIEDNYEELRAATESIYPEKPDLEFAFIIYDVVDSSNQQKVDEFYYKYKDQIFSEVSSIQLGNWTLLGSFKANRERYNYFNQNNEIIKRILDRHEEDLKIGKEILRNTIYHKKAKNIQETGPDAPGLSIYNSTFHTDSGIKGLLSFKELKNLEKASGNIKKAREYDFIDDCEEKIKQLLSKENLTPDEESELIKTKKQLDNALEMLNVPDDTIRVDMWVNNNNKLEKEILYTKAEL

Function

Plays an essential role in the assembly of the icosahedral capsid of the virus.

Similarity

Belongs to the asfivirus B602L family.

Keywords

Complete proteome Host cytoplasm Reference proteome Repeat

Feature

chain Protein B602L

Uniprot

A9JLW5 A0A0A1E0R9 A9JL36 Q65169 D4I5R8 A0A0N7CUR3 + More
A0A0A1E342 A0A386RTM6 A0A386RTQ2 A0A386RV05 A0A386RU95 Q8V9S9 A0A1I9XG42 A0A3G1EV30 E0WML8 A0A2X0SE03 A0A2Z5DGB7 A0A2Z5DGF5 A0A0C5BCQ1 A0A1B0VAM7 P0CAI0 A0A0C5BC88 P0CAI1 P0CAI2 A0A1C6ZXX6 A0A1B0V7L8 A0A1B0V606 A0A1V0CNU7

Pubmed

18198370 25406173 11831707 17035321 26618713 21470447 + More
25645905 27211823 27801826

EMBL

AM712240 CAN10429.1 KM262845 AIY22429.1 AM712239 CAN10179.1 + More
U18466 FN557520 CBH29181.1 KP055815 AKO62761.1 KM262844 AIY22271.1 MG596383 MG596391 AYE66934.1 AYE66942.1 MG596388 AYE66939.1 MG596379 MG596380 MG596384 MG596385 MG596386 MG596387 MG596389 MG596390 MG596392 MG596393 AYE66930.1 AYE66931.1 AYE66935.1 AYE66936.1 AYE66937.1 AYE66938.1 AYE66940.1 AYE66941.1 AYE66943.1 AYE66944.1 MG596381 MG596382 AYE66932.1 AYE66933.1 L00966 AY261361 KT961377 APA62539.1 KX354450 AOO54419.1 FR682468 CBW46746.1 MH744810 MG939583 MG939587 MG939588 LS478113 AXP99041.1 AXZ95854.1 AXZ96042.1 AXZ96137.1 SPS73503.1 MH025916 MH025917 MH025918 MH025920 AXB49308.1 AXB49482.1 AXB49654.1 AXB49998.1 MH025919 AXB49825.1 KM111295 AJL34258.1 KT795376 KT795377 AMQ11023.1 AMQ11024.1 AY261360 KM111294 AJL34093.1 AY261363 AY261366 KM102979 AJZ77057.1 KT795378 AMQ11025.1 KT795379 AMQ11026.1 KX552040 ARA72022.1

Proteomes

UP000108903 UP000110401 UP000130745 UP000000624 UP000101090 UP000241813 + More
UP000142390 UP000000860 UP000266411 UP000141072 UP000101566 UP000000861 UP000105860 UP000000859 UP000000858 UP000117635 UP000204182

ProteinModelPortal

A9JLW5 A0A0A1E0R9 A9JL36 Q65169 D4I5R8 A0A0N7CUR3 + More
A0A0A1E342 A0A386RTM6 A0A386RTQ2 A0A386RV05 A0A386RU95 Q8V9S9 A0A1I9XG42 A0A3G1EV30 E0WML8 A0A2X0SE03 A0A2Z5DGB7 A0A2Z5DGF5 A0A0C5BCQ1 A0A1B0VAM7 P0CAI0 A0A0C5BC88 P0CAI1 P0CAI2 A0A1C6ZXX6 A0A1B0V7L8 A0A1B0V606 A0A1V0CNU7

PDB

3Q5X E-value=4.93887, Score=71

Ontologies

KEGG

vg:22220309

GO

GO:0030430 C:host cell cytoplasm

Subcellular Location

From MSLVP

Cytoplasm

From Uniprot

Host cytoplasm

Topology

Length:

530

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04295

Exp number, first 60 AAs:

0.00577

Total prob of N-in:

0.00242

outside

1 - 530

Population Genetic Test Statistics

Pi

0.0243448

Theta

0.0248662

Tajima's D

-0.7855004

CLR

0.210885

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein Protein	QED21663.1 AKO62761.1
China_AnhuiXCGQ_2018	Protein Protein	QED21663.1 AYW34051.1
China_ASFV-SY18_2018	Protein	AKO62761.1
Poland_Pol16_20186_o7_2016-2017	Protein Protein	QED21663.1 AXZ95854.1
Poland_Pol16_20538_o9_2016-2017	Protein	CAN10429.1
Poland_Pol16_20540_o10_2016-2017	Protein Protein	CAN10429.1 QED21663.1
Poland_Pol16_29413_o23_2016-2017	Protein Protein	CAN10429.1 QED21663.1
Poland_Pol17_03029_C201_2016-2017	Protein Protein	QED21663.1 AXZ96042.1
Poland_Pol17_04461_C210_2016-2017	Protein Protein	QED21663.1 AXZ96137.1
Poland_Pol17_05838_C220_2016-2017	Protein Protein	CAN10429.1 QED21663.1
Poland_ASFV_POL_Podlaskie_2015	Protein Protein	CAN10429.1 QED21663.1
Uganda_R8_2015	Protein	AXB49308.1
Uganda_R7_2015	Protein	AXB49482.1
Uganda_R25_2015	Protein	AXB49654.1
Uganda_N10_2015	Protein	AXB49825.1
Uganda_R35_2015	Protein	AXB49998.1
Estonia_2014	Protein Protein	QED21663.1 SPS73503.1
Italy_26544_OG10_2010	Protein	AJZ77057.1
Italy_47_Ss_2008_2008	Protein	AOO54419.1
Portugal_OURT_88.3_1988	Protein Protein Protein	CAN10429.1 QED21663.1 CAN10429.1
Spain_E75_1975	Protein Protein	QED21663.1 CBH29181.1
Russia_Georgia_2007	Protein Protein	QED21663.1 CBW46746.1
Kenya_Tk1_2005	Protein	AJL34093.1
Kenya_Bus_2006	Protein	AJL34258.1
Russia_Odintsovo_2014	Protein	CAN10429.1
Portugal_L60_1960	Protein Protein	QED21663.1 AIY22271.1
Portugal_NHV_1968	Protein Protein	QED21663.1 AIY22429.1
Russia_Kashino_2013	Protein Protein	CAN10429.1 QED21663.1
Benin_1997	Protein	CAN10179.1
South_Africa_KNP_Pretorisuskop_1996	Protein	CAN10429.1
South_Africa_MGR_Mkuzi_1979	Protein	CAN10429.1
Malawi_Lil_1983
Kenya_1950	Protein	CAN10429.1
Namibia_Warthog_1980	Protein	CAN10429.1
South_Africa_Warmbaths_1987	Protein	CAN10429.1
Malawi_Tengani_1962	Protein	CAN10429.1
China_HLJ_2018	Protein Protein	QED21663.1 QBH90568.1
China_LN_2018	Protein Protein	QED21663.1 QBH90753.1
China_wbBS01_2018	Protein Protein	QED21663.1 QDL88111.1
Ukraine_Kyiv_2014	Protein	QED21662.1
Belgium_Etalle_wb_2018	Protein Protein	QED21663.1 QED90523.1
Lithuania_LT14_2014	Protein Protein	QED21663.1 QEY87886.1
South_Africa_1985
South_Africa_2_2008
Zambia_LIV_1983

Sequence