ASFVdb The African Swine Fever Virus Database
Strain
Poland_ASFV_POL_Podlaskie_2015 (Region: Poland;  Strain: ASFV/POL/2015/Podlaskie;  Date: 2015)
Gene
MGF 505-7R
Description
With frameshift mutation but translatable,  Member of multigene family 505 (A528R)
GenBank Accession
Full name
Protein MGF 505-7R       + More
Protein MGF 505-6R      
Protein MGF 505-10R      
Protein MGF 505-2R      
Protein MGF 505-5R      
Protein MGF 505-4R      
Protein MGF 505-1R      
Protein MGF 505-9R      
 

Sequence

CDS
ATGTTCTCCCTTCAGGACCTCTGTCGGAAGAACACCTTCTTCCTTCCAAGTGATTTTAGCAAGCATACCCTGCATTTGCTGGGGTTATACTGGAAGGGGCATGGATCTATCCAAAGGATAAAGAATGATGGTGTGCTTATAGAGCATGATCTTACTCTTTCCATCAATGAAGCCTTAATTCTTGCAGGAGAAGAGGGAAACAATGAAGTAGTAAAGCTCTTGTTACTATGGGAAGGAAATCTTCATTATGCCATCATAGGAGCTTTGAGGACTGAGAACTATAACCTAGTATGTGAGTACCATAGTCAAATTCAGGACTGGCATGTTCTCCTCCCTTTGATTCAAGATCCAGAAACATTCGAAAAATGTCATGATTTAAGCCTTGAATGTGATCTTTCATGCCTTCTCCAACATGCTGTAAAATATAACATGCTTTCGATTCTTGTTAAATATAAAGAGGATCTACTAAATGTACTATTTAGGCAACAAATTCAAGGACTATTTATTTTAGCATGTGAAAATCGGAAGCTTGAGATTCTTACGTGGATGGGTCAAAATCTGCCAATTCCTGATCCTGAGCCTATTTTTAGCATTGCTGTTGTCACAAAAGATTTAGAAATGTTTTCCTTAGGGTACAAGATTGTTTTTGAATACATGGAAAACCAAGGACTTCATTTAACCCAGGTAGTTCGTATGGTTATGCTAAATCATCACTTTGGCATGGTAATAAATAAAGGACTTTTACCCTTTGTGCTGGAAATTTTAAATTATGGTGGGAATGTAAATAGAGCCTTATCTTATGCTGTCACACAAAATAAAAGAAAGATTTTAGACCATGTTGTTCGCCAAAAGAATATACCCCATAAAACCATTGAAAGAATGTTGCATCTGGCTGTAAAAAAGCATGCTCCCAGGAAAACTCTGAACTTGTTACTATCTTACATAAATTACAAGGTGAAAAATGTTAAAAAGTTGTTAGAACATGTAGTGAAATACAACTCTACTCTTGTGATAAGACTCTTGTTAGAAAAAAAGAAAAACCTGCTGGATGCTACTTTGACAAGATATGTCAAAGATTCTACATACTTTCAGGTGAAAGAATTTATGCAAGACTTCTCCATCAGCCCAGAAAAATTCATTAAAATAGCTGTGCGGGAAAAGAGAAATGTGTTGATCAAGGGTATTTCTGAAGATATTTGGGAAAATCCCGCGGAAAGAATCAGGAATCTTAAGCAGATAGTGTGTACCATAAAATATGAAAGTGGAAGACAATTCCTGATAAATATCATTCACACCATTTACCAGAGTTATTCTTTGAAACCTGAAGAAATTCTTAAATTGGCAACATTTTATGTCAAACACAATGCAACCACCCATTTTAAAGATCTCTGCAAATATCTTTGGCTGAACAGAAGAACAGAAAGTAAGAAACTGTTTTTAGAGTGCTTGGAAATTGCTGATAAGAAGGAGTTTCCTGATATTAAAAGTATTGTGAGTGAATACATTAACTATTTGTTTACTGCAGGAGCTATTACCAAGGAAGAAATCATGCAAGCCTATGCTTTGGAGTATGCCATGTATTAA
Protein
MFSLQDLCRKNTFFLPSDFSKHTLHLLGLYWKGHGSIQRIKNDGVLIEHDLTLSINEALILAGEEGNNEVVKLLLLWEGNLHYAIIGALRTENYNLVCEYHSQIQDWHVLLPLIQDPETFEKCHDLSLECDLSCLLQHAVKYNMLSILVKYKEDLLNVLFRQQIQGLFILACENRKLEILTWMGQNLPIPDPEPIFSIAVVTKDLEMFSLGYKIVFEYMENQGLHLTQVVRMVMLNHHFGMVINKGLLPFVLEILNYGGNVNRALSYAVTQNKRKILDHVVRQKNIPHKTIERMLHLAVKKHAPRKTLNLLLSYINYKVKNVKKLLEHVVKYNSTLVIRLLLEKKKNLLDATLTRYVKDSTYFQVKEFMQDFSISPEKFIKIAVREKRNVLIKGISEDIWENPAERIRNLKQIVCTIKYESGRQFLINIIHTIYQSYSLKPEEILKLATFYVKHNATTHFKDLCKYLWLNRRTESKKLFLECLEIADKKEFPDIKSIVSEYINYLFTAGAITKEEIMQAYALEYAMYX

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Similarity
Belongs to the asfivirus MGF 505 family.
Keywords
ANK repeat   Complete proteome   Repeat   Reference proteome  
Feature
chain  Protein MGF 505-7R
EMBL
KX354450    AOO54356.1    KP055815    AKO62712.1    FN557520    CBH29131.1    + More
AM712239    CAN10129.1    KM262844    KM102979    AIY22221.1    AJZ77061.1    AM712240    CAN10378.1    KM262845    AIY22380.1    AY261363    AY261366    FR682468    CBW46695.1    LS478113    SPS73452.1    AY261361    CBH29130.1    CAN10377.1    AIY22220.1    AIY22379.1    AJZ77060.1    AKO62711.1    AOO54355.1    CAN10128.1    U02468    U18466    KM111295    AJL34210.1    MH025916    MH025917    MH025918    MH025919    MH025920    AXB49259.1    AXB49433.1    AXB49605.1    AXB49776.1    AXB49949.1    AY261360    KM111294    AJL34045.1    CBW46694.1    MG939583    MG939587    MG939588    AXZ95807.1    AXZ95995.1    AXZ96090.1    SPS73451.1    CBW46689.1    AXZ95802.1    AXZ95990.1    AXZ96085.1    SPS73446.1    U03761    AJL34047.1    AJL34212.1    AXB49261.1    AXB49435.1    AXB49607.1    AXB49778.1    AXB49951.1    CBW46697.1    AXZ95809.1    AXZ95997.1    AXZ96092.1    SPS73454.1    U03762    AXB49255.1    AXB49429.1    AXB49601.1    AXB49773.1    AXB49945.1    CBH29133.1    AJL34206.1    CAN10127.1    CBH29129.1    AIY22219.1    AJZ77066.1    AKO62710.1    AOO54354.1    CAN10376.1    AIY22378.1    CAN10380.1    AIY22382.1    AJL34209.1    AXB49258.1    AXB49432.1    AXB49604.1    AXB49775.1    AXB49948.1    AIY22223.1    AKO62714.1    AJZ77055.1    AOO54359.1    CAN10131.1    CAN10124.1    AIY22216.1    AJZ77062.1    AKO62707.1    AOO54349.1    CBH29126.1    AJL34044.1    AJL34041.1    AXZ95806.1    AXZ95994.1    AXZ96089.1    CBW46693.1    SPS73450.1    CAN10126.1    CBH29128.1    CAN10375.1    AIY22218.1    AIY22377.1    AJZ77065.1    AKO62709.1    AOO54353.1    AXB49257.1    AXB49431.1    AXB49603.1    AXB49947.1    AJL34208.1    CBW46692.1    AXZ95993.1    AXZ96088.1    SPS73449.1    AXZ95805.1    AJL34043.1    AJL34037.1    AJL34201.1    AXB49251.1    AXB49425.1    AXB49597.1    AXB49770.1    AXB49941.1    CAN10120.1    CBH29122.1    AIY22212.1    AKO62703.1    AJZ77058.1    AOO54340.1    CBW46685.1    AXZ95798.1    AXZ95986.1    AXZ96081.1    SPS73442.1    AJL34211.1    AXB49260.1    AXB49434.1    AXB49606.1    AXB49777.1    AXB49950.1   
Pfam
PF03158   DUF249
Interpro
IPR004858   MGF_505
IPR036770   Ankyrin_rpt-contain_sf
SUPFAM
SSF48403   SSF48403
Gene 3D
PDB
5OF3     E-value=0.0310154,     Score=89

Ontologies

Subcellular Location

From MSLVP
Capsid

Topology

Length:
528
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.0806399999999998
Exp number, first 60 AAs:
0.00411
Total prob of N-in:
0.00327
outside
1  -  528
 
 

Population Genetic Test Statistics

Pi
0.0683301
Theta
0.0796494
Tajima's D
-0.727042
CLR
0.009836
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
Protein
AKO62711.1
AKO62712.1
China_AnhuiXCGQ_2018 Protein
Protein
AYW34000.1
AYW34001.1
China_ASFV-SY18_2018 Protein
Protein
AKO62711.1
AKO62712.1
Poland_Pol16_20186_o7_2016-2017 Protein
Protein
CAN10129.1
AXZ95807.1
Poland_Pol16_20538_o9_2016-2017 Protein
CAN10129.1
Poland_Pol16_20540_o10_2016-2017 Protein
CAN10129.1
Poland_Pol16_29413_o23_2016-2017 Protein
CAN10129.1
Poland_Pol17_03029_C201_2016-2017 Protein
Protein
CAN10129.1
AXZ95995.1
Poland_Pol17_04461_C210_2016-2017 Protein
Protein
CAN10129.1
AXZ96090.1
Poland_Pol17_05838_C220_2016-2017 Protein
Protein
CAN10129.1
QGM12818.1
Poland_ASFV_POL_Podlaskie_2015 Protein
CAN10129.1
Uganda_R8_2015 Protein
AXB49259.1
Uganda_R7_2015 Protein
AXB49433.1
Uganda_R25_2015 Protein
AXB49605.1
Uganda_N10_2015 Protein
AXB49776.1
Uganda_R35_2015 Protein
AXB49949.1
Estonia_2014 Protein
Protein
SPS73451.1
SPS73452.1
Italy_26544_OG10_2010 Protein
Protein
AJZ77060.1
AJZ77061.1
Italy_47_Ss_2008_2008 Protein
Protein
AOO54355.1
AOO54356.1
Portugal_OURT_88.3_1988 Protein
Protein
CAN10377.1
CAN10378.1
Spain_E75_1975 Protein
Protein
CBH29130.1
CBH29131.1
Russia_Georgia_2007 Protein
Protein
CBW46694.1
CBW46695.1
Kenya_Tk1_2005 Protein
AJL34045.1
Kenya_Bus_2006 Protein
AJL34210.1
Russia_Odintsovo_2014 Protein
CAN10129.1
Portugal_L60_1960 Protein
Protein
AIY22220.1
AIY22221.1
Portugal_NHV_1968 Protein
Protein
AIY22379.1
AIY22380.1
Russia_Kashino_2013 Protein
CAN10129.1
Benin_1997 Protein
Protein
Protein
CAN10129.1
CAN10128.1
CAN10129.1
South_Africa_KNP_Pretorisuskop_1996 Protein
CAN10129.1
South_Africa_MGR_Mkuzi_1979 Protein
CAN10129.1
Malawi_Lil_1983    
Kenya_1950    
Namibia_Warthog_1980 Protein
CAN10129.1
South_Africa_Warmbaths_1987 Protein
CAN10129.1
Malawi_Tengani_1962 Protein
CAN10129.1
China_HLJ_2018 Protein
Protein
QBH90516.1
QBH90517.1
China_LN_2018 Protein
Protein
QBH90701.1
QBH90702.1
China_wbBS01_2018 Protein
Protein
QDL88059.1
QDL88060.1
Ukraine_Kyiv_2014 Protein
Protein
QED21586.1
QED21587.1
Belgium_Etalle_wb_2018 Protein
Protein
QED90471.1
QED90472.1
Lithuania_LT14_2014 Protein
Protein
QEY87834.1
QEY87835.1
South_Africa_1985 Protein
CAN10129.1
South_Africa_2_2008 Protein
QGM12819.1
Zambia_LIV_1983    
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