ASFVdb The African Swine Fever Virus Database
Strain
Russia_Odintsovo_2014 (Region: Russia;  Strain: Odintsovo_02/14;  Date: 2014)
Gene
BA71V-B962L
Description
With frameshift mutation but translatable,  similar to African swine fever virus E75 strain E75 of INSD accession FN557520
Location
KP843857.1(-):92091-94979
GenBank Accession
AJL34086.1
Full name
Putative RNA Helicase B962L       + More
Putative RNA helicase B962L      
 

Sequence

CDS
ATGGGAAAACCGACTTTATTGGAGCCTGGTCATCTCTATAACGTGCCCGCTGAGCACAAGAATGATGTTCCTATTCATTACATCATCACTTGGATAAAACAACGTCTCCCGGAGTTTGGAGGGGCCATTCCAACCTCCCTCGCAGACCGGGTGCTCATTATAAAGTCACGCACTGGTTCCGGAAAATCCACGGCCTTACCCGTACACGTGTTCAGAATTCTGAGAAATGAAAACACGCATTCTTTCCAAAAATACTTGGGACGCTCGGTTATTTGTACCCAGCCAAGAGTCCTAACCGCGGTGACCCTCGCCAAAGACATCGGCGCCTCAACCCACTACCCCGACATGATATTAGGCCAAACAGTGGGCTACCAAACGAAGCCTCTGACGGAAAAACCCAATCGGGGCCTTATTTATGCAACCGCGGGGGTTCTGTTGGCGCAGCTACATACAATGACGGATGATGAGATAGCTTCCCGCTATGCCTTTATGATTATAGATGAGGCCCATGAGCGAGCCCTAGGCATCGACCTTATGCTCATGTATATTAAAAGTATGCTTCAGCGCATGTTGCAAAGAGGAAGCATAGGGGCGCTGCGTATTCCCTTTGTAATTTTAACCTCCGCCACCATTGATACCCATAAATACTCAACCTATTTTGGTATCGGAAAAGAAAACATTATTTTGGTGGAAGGACGACAGTACGGTGTGGAAACCCACTGGCCGCTGTATAACACCAACAACTACATTAAGACCGCCTGCGAAACGGCTCTCACTATTCATAAAGAAAACATTCATGATCGTCCCACGGAAGCAGATATTTTAATTTTCATGCCCGGTATGGCTGAAATACGCTTCCTTTCGATGTTGCTGAATAATGCAAATATGGACCTTGCCAAAGAAAAGCTGCCGTTAATGTTGATTTTGCCGATCGATAGTGAGGCGATTGCGCAGGAAAATGAGGCCTACCTTGGCCTGAAAGCGGAAATTAAGAATCTGTGGGTGAAAAATCCCTTAACCGCTAAAGTGGAAAAACCTTTAAGAAGGGTCATTGTTTCCACGGTTGTTGCGGAAACGGGCCTTACCATTGAAACGCTGAAGTACGTCATAGATCCCGGGTGGAACAGAAGCATTGAAACCTACTATCCCGAATGGGCGGGAGGGCTTATTACGCGCCCCGCGGCTCAAAGCCGTATCGAGCAAAGAAAGGGGCGTGTAGGGAGAGTATTTCCTGGGCACTTTTACCCGCTTTACACAAAACACGTCTTTGAGCAAATACCAGTGCAGCAGTATCCTGAAATCATTACGGAAGGCCCTGGGGCCATTTTTCTTAGCATTGTCGTAGAAACGATTAAAAAAAATAAGGAAGGCGTGTTTAAGGCAGAGGAGATTGATATGCTGGATCCTCCCCCCACGGATGCGCTGGCATCAGCCATTGAGCGGGCCATTGTGGCAGGCCTTTTAACCAGAGGAGAAAAAGGTCTTCAACTCACGCAGCTCGGAGACATTGCCTCTCGCTTTTCGTTTTTATCTATAGAAGAAGCGCGCATGTGCTTTTCGGGTTATTTCTGGCAAGCCGCCATTTCTGACATTGCAACCATCCTAGCCGTCGTGTCTGTTGCGGACAAAAAACTTACGAATCTATTGGACAGTAAACAACGGAACGGAGCTATGCTTGCTGAAGCGGTTTTGGCAGGCATTCCGCCGTTTCTACAAAATATTGACAATGCTTACACCAACATCCATCTTCTATTGGCAGATGATCTTTTGGAGGGGCTCTTTATTTTTGAAGGCTTCCAACATGCCATCGTATACTTTATCAATAATAAGGTTAATAATGTAGCTAAACATCTTCGCGAATGGTGCGAAAAAAAAATGCTAAAGTATTCTTCTATGGTGCAGATTTTAGCGCGCCGCGAAGATATTTTAAACGAGCTGGCCATTGTAGGATTGAACCCCTTCCACCAATGGCAAAACCGCTTGGCCTCCGCCAATGCAGAAACCTTTTTAAAACGTGTTTGTACTTTGAAACAGTGTATGTATGAGGCATACCGCCTTAATTGTTTCTGCTACGACGAACATAGGCTTCTTTATACTGGAAGAAATGGAATACACTTTTCTTACCACGATGCGGTGATTAAAAACCCTTCGTGCATTGTGACGCCTAGGATTATGCTATCTCCCGTTTCTAAACAGTATATGGAATGGAGATTAGAGCCAAGCTTTGTGTCCGTCCTCGATGGATTCGTAAACGTGGACATAAACTTTCTTTTGCCACGTCAGGAAATTCCAAATATTTTGGGAGGCGTCGAGAACGAAGAGGAGGAGCCCCCTCTGCCCATTCAGGTATTTTTACATAAATACGTAAAGACCCATTTTCACTTCTCCGGGAAATCCTTTAAAGAGTTGAAAATGAAGCCTAGTCAGATGATTAAGTTTCCCGAAACAACCTTAATCAACATGATTCCCGATATACCTAAAAACGTAGTGCAAACCTACTTGGAAATAAATGTTTGTCATCGATACTCGTTTAAGCGTCTCATTTACTGTGAAACGTTTTATACCGATATGGACGATGTCCAGCATGAAAACTCTGTGGAGCTCATAGGGTTACCTATGGCGGCGCATCATCTTACGATAAACGATTTTAACAAGCTTTACCATCTGTTGAAACCTGATGGTTTTCTTATCATGTACGACCTTCATCAAGGTCAGGAGGCCTTCTGGCTTCACAGCCTGCAGGACGCACTTGGGCACCATACTATTCGTAGAGACATGGATTTCCATACCATCCCCGAATGGGAAACCATATTTAAAGAATGCGGATTCACACCGATTTTTAGTAAACAGCCTTCGGAGCACGAACTGTTCATCGTATTTAAAAAATAA
Protein
MGKPTLLEPGHLYNVPAEHKNDVPIHYIITWIKQRLPEFGGAIPTSLADRVLIIKSRTGSGKSTALPVHVFRILRNENTHSFQKYLGRSVICTQPRVLTAVTLAKDIGASTHYPDMILGQTVGYQTKPLTEKPNRGLIYATAGVLLAQLHTMTDDEIASRYAFMIIDEAHERALGIDLMLMYIKSMLQRMLQRGSIGALRIPFVILTSATIDTHKYSTYFGIGKENIILVEGRQYGVETHWPLYNTNNYIKTACETALTIHKENIHDRPTEADILIFMPGMAEIRFLSMLLNNANMDLAKEKLPLMLILPIDSEAIAQENEAYLGLKAEIKNLWVKNPLTAKVEKPLRRVIVSTVVAETGLTIETLKYVIDPGWNRSIETYYPEWAGGLITRPAAQSRIEQRKGRVGRVFPGHFYPLYTKHVFEQIPVQQYPEIITEGPGAIFLSIVVETIKKNKEGVFKAEEIDMLDPPPTDALASAIERAIVAGLLTRGEKGLQLTQLGDIASRFSFLSIEEARMCFSGYFWQAAISDIATILAVVSVADKKLTNLLDSKQRNGAMLAEAVLAGIPPFLQNIDNAYTNIHLLLADDLLEGLFIFEGFQHAIVYFINNKVNNVAKHLREWCEKKMLKYSSMVQILARREDILNELAIVGLNPFHQWQNRLASANAETFLKRVCTLKQCMYEAYRLNCFCYDEHRLLYTGRNGIHFSYHDAVIKNPSCIVTPRIMLSPVSKQYMEWRLEPSFVSVLDGFVNVDINFLLPRQEIPNILGGVENEEEEPPLPIQVFLHKYVKTHFHFSGKSFKELKMKPSQMIKFPETTLINMIPDIPKNVVQTYLEINVCHRYSFKRLIYCETFYTDMDDVQHENSVELIGLPMAAHHLTINDFNKLYHLLKPDGFLIMYDLHQGQEAFWLHSLQDALGHHTIRRDMDFHTIPEWETIFKECGFTPIFSKQPSEHELFIVFKK

Summary

Catalytic Activity
ATP + H2O = ADP + H(+) + phosphate
Similarity
Belongs to the DEAD box helicase family. DEAH subfamily.
Keywords
ATP-binding   Complete proteome   Helicase   Host membrane   Hydrolase   Membrane   Nucleotide-binding   Transmembrane   Transmembrane helix   Reference proteome  
Feature
chain  Putative RNA Helicase B962L
Uniprot
A0A0C5B261   Q8V9U2   E0WML1   A0A2X0RUB3   P0C9A2   A9JL25   + More
D4I5R1   A9JLV9   A0A0A1E087   P0C9A3   Q89443   A0A2Z5DGJ6   P0C9A4   A0A0C5B2K3   A0A141ZMQ8   A0A1X6WG48   A0A1X7QFH0   A0A1X7BZD4   A0A0H3TM28   A0A141ZIH4  
Pubmed
25645905    21470447    18198370    25406173    26618713    11831707    + More
26903952    25878099   
EMBL
KM111294    AJL34086.1    L00966    AY261361    FR682468    CBW46739.1    + More
MG939583    MG939587    MG939588    LS478113    AXZ95847.1    AXZ96035.1    AXZ96130.1    SPS73496.1    AY261363    AM712239    CAN10172.1    FN557520    CBH29174.1    AM712240    CAN10422.1    KM262844    KM262845    KM102979    KP055815    KX354450    AIY22264.1    AIY22422.1    AJZ77048.1    AKO62754.1    AOO54411.1    AY261366    L10062    U18466    MH025919    AXB49818.1    AY261360    KM111295    MH025916    MH025917    MH025918    MH025920    AJL34251.1    AXB49301.1    AXB49475.1    AXB49647.1    AXB49991.1    KU702949    KU702951    KU556803    AMN83808.1    AMN84526.1    AMP44332.1    LT706986    SIP85844.1    CZDJ02000003    SMH63328.1    LT839607    SME64767.1    KJ614390    KU702950    AIB51810.1    AMN84026.1    KU702948    KU702952    AMN83042.1    AMN85012.1   
Proteomes
UP000105860    UP000000860    UP000141072    UP000000859    UP000130745    UP000101090    + More
UP000108903    UP000110401    UP000117635    UP000142390    UP000241813    UP000266411    UP000000858    UP000000624    UP000000861    UP000101566    UP000244556    UP000244783    UP000244814    UP000201921    UP000244303    UP000244833    UP000244713    UP000244774   
Pfam
PF00270   DEAD
PF00271   Helicase_C
Interpro
IPR011545   DEAD/DEAH_box_helicase_dom
IPR027417   P-loop_NTPase
IPR029063   SAM-dependent_MTases
IPR014001   Helicase_ATP-bd
IPR001650   Helicase_C
IPR002464   DNA/RNA_helicase_DEAH_CS
SUPFAM
SSF53335   SSF53335
SSF52540   SSF52540
ProteinModelPortal
A0A0C5B261   Q8V9U2   E0WML1   A0A2X0RUB3   P0C9A2   A9JL25   + More
D4I5R1   A9JLV9   A0A0A1E087   P0C9A3   Q89443   A0A2Z5DGJ6   P0C9A4   A0A0C5B2K3   A0A141ZMQ8   A0A1X6WG48   A0A1X7QFH0   A0A1X7BZD4   A0A0H3TM28   A0A141ZIH4  
PDB
5Y88     E-value=1.15094e-42,     Score=440

Ontologies

KEGG
vg:22220302    
GO
GO:0003676  F:nucleic acid binding
 GO:0005524  F:ATP binding
 GO:0033644  C:host cell membrane
 GO:0004386  F:helicase activity
 GO:0016021  C:integral component of membrane

Subcellular Location

From MSLVP
Single-Pass Membrane
From Uniprot
Host membrane  

Topology

Length:
962
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.13985
Exp number, first 60 AAs:
0.00019
Total prob of N-in:
0.00161
outside
1  -  962
 
 

Population Genetic Test Statistics

Pi
0.0276597
Theta
0.0386839
Tajima's D
-0.9626866
CLR
0.060856
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AKO62754.1
China_AnhuiXCGQ_2018 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AYW34044.1
China_ASFV-SY18_2018 Protein
 AKO62754.1
Poland_Pol16_20186_o7_2016-2017 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AXZ95847.1
Poland_Pol16_20538_o9_2016-2017 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
Poland_Pol16_20540_o10_2016-2017 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
Poland_Pol16_29413_o23_2016-2017 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
Poland_Pol17_03029_C201_2016-2017 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AXZ96035.1
Poland_Pol17_04461_C210_2016-2017 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AXZ96130.1
Poland_Pol17_05838_C220_2016-2017 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
Poland_ASFV_POL_Podlaskie_2015 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
Uganda_R8_2015 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AXB49301.1
Uganda_R7_2015 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AXB49475.1
Uganda_R25_2015 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AXB49647.1
Uganda_N10_2015 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AXB49818.1
Uganda_R35_2015 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AXB49991.1
Estonia_2014 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
SPS73496.1
Italy_26544_OG10_2010 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AJZ77048.1
Italy_47_Ss_2008_2008 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AOO54411.1
Portugal_OURT_88.3_1988 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
CAN10422.1
Spain_E75_1975 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
CBH29174.1
Russia_Georgia_2007 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
CBW46739.1
Kenya_Tk1_2005 Protein
Protein
Genetic Remain
Protein
 AJL34086.1
QED21648.1
QED21650.1
AJL34086.1
Kenya_Bus_2006 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AJL34251.1
Russia_Odintsovo_2014 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
Portugal_L60_1960 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AIY22264.1
Portugal_NHV_1968 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
AIY22422.1
Russia_Kashino_2013 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
Benin_1997 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
CAN10172.1
South_Africa_KNP_Pretorisuskop_1996 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
South_Africa_MGR_Mkuzi_1979 Protein
Protein
 AJL34086.1
QED21648.1
Malawi_Lil_1983 Genetic Remain
Protein
Protein
 AJL34086.1
QED21648.1
QED21650.1
Kenya_1950 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
Namibia_Warthog_1980 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
South_Africa_Warmbaths_1987 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
Malawi_Tengani_1962 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
China_HLJ_2018 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
QBH90561.1
China_LN_2018 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
QBH90746.1
China_wbBS01_2018 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
QDL88104.1
Ukraine_Kyiv_2014 Protein
Protein
Protein
 QED21646.1
QED21647.1
QED21649.1
Belgium_Etalle_wb_2018 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
QED90516.1
Lithuania_LT14_2014 Protein
Genetic Remain
Protein
 QED21648.1
QED21650.1
QEY87879.1
South_Africa_1985 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
South_Africa_2_2008 Protein
Protein
Genetic Remain
 AJL34086.1
QED21648.1
QED21650.1
Zambia_LIV_1983 Protein
Genetic Remain
 QED21648.1
QED21650.1
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