Strain

Kenya_Bus_2006 (Region: Kenya;  Strain: Ken06.Bus;  Date: 2006)

Gene

BA71V-A240L

Description

Annotated in NCBI,  similar to African swine fever virus E75 strain E75 of INSD accession FN557520

Location

KM111295.1(-):44136-44666

GenBank Accession

AJL34215.1

Full name

Thymidylate kinase       + More
Truncated thymidylate kinase      

Alternative Name

dTMP kinase

CDS

ATGCCATCAGAAGAATTGCACGGATTATTCACAAAACATCGATGTGAATTTACGGCAGAAATTGCAGCACTACTTAAACTAAATTTTATTGTAATTGTGGACCGTTATATTTGGTCTGGTTTGGCATATGCTCAAGCAGACAGAATAATGATTGATACCAAAAATACTTTCAATCCGGATTACACATTCTTTTTATCTTCAAACAAACCATTAAATGAAAAACCCTTACATTTACAACGATTGTATGAAACAGAAGAAAAACAAGAAATAATTTTTACTCAATTTATTAATATCATAAATGAAGTACCTAAAAATAAGTTTTGTATTATTCCTGCAAATCTTAATAAGGAAATAATTGATAAGATCATTTTCTCAAAAACGATAAAAGTTTTTGAGAAAAACTTAAATTTAGACTATATTAAAATGTATGATGGTATGTATTTTAATATTCACGACTTAGATTTAATCCGTTTTGATTGGCAAAAATGTATTGAAGAAGATGATGGCATAGATGAGGAACACGGATTATAA

Protein

MPSEELHGLFTKHRCEFTAEIAALLKLNFIVIVDRYIWSGLAYAQADRIMIDTKNTFNPDYTFFLSSNKPLNEKPLHLQRLYETEEKQEIIFTQFINIINEVPKNKFCIIPANLNKEIIDKIIFSKTIKVFEKNLNLDYIKMYDGMYFNIHDLDLIRFDWQKCIEEDDGIDEEHGL

Catalytic Activity

ATP + dTMP = ADP + dTDP

Similarity

Belongs to the thymidylate kinase family.

Keywords

ATP-binding   Complete proteome   Kinase   Nucleotide biosynthesis   Nucleotide-binding   Transferase   Reference proteome  

Feature

chain  Thymidylate kinase

Uniprot

A0A0C5AZW1   A0A2Z5DGC8   A0A0C5AZC7   P0C8F9   P0C8G2   E0WMH3   + More
A0A2X0RUU2   A0A0N6WHZ1   P0C8G1   P0C8G0   A9JKX1   D4I5M3   A9JLM6   A0A0A1E300   P42490   W0TBV7   G0W9J5   C4R413   F2QWX9   A0A1G4JA25   G8BUP5   A0A1B0G795   A0A1B2J889   W8C5G7   A0A1A9XUE6   A0A376B211   C5DDP8   A0A1D2VEJ9   A7TM70   A0A1E3QYN2   A0A3F2Y7Z2   Q6FSB3   A0A120K2I1   A0A0W0CHT6   A0A1L0BZZ3   A0A1L0DNP7   A0A1G4ISA8   A0A1Q3A4X7   C5DZH9   G8ZW73   A0A1S7HID8   S6E0Z3   A0A212M3W0   A0A212EPA4   I2H8I5   A0A1Q3AJ63   A0A1Y3DNB9   A0A384L2E6   A0A1W4VCF3   G3B8F2   A0A3B0J316   A0A2V1AZ45   G0VIJ1   L0AUF2   A0A0C7MZG8   A0A1G4J8U9   B6AIV4   A0A1S7HVA4  

Pubmed

25645905    21470447    26618713    18198370    25406173    8393914    + More
11831707    25834639    22123960    19465926    21575661    27388471    24495485    19525356    17494770    15229592    23969048    22118469    21788494    23137308   

EMBL

KM111295    AJL34215.1    MH025916    MH025917    MH025918    MH025919    + More
MH025920    AXB49264.1    AXB49438.1    AXB49610.1    AXB49781.1    AXB49954.1    KM111294    AJL34050.1    AY261360    AY261366    FR682468    CBW46701.1    MG939583    MG939587    MG939588    LS478113    AXZ95812.1    AXZ96000.1    AXZ96095.1    SPS73458.1    KP055815    AKO62717.1    AY261363    AY261361    AM712239    CAN10134.1    FN557520    CBH29136.1    AM712240    CAN10383.1    KM262844    KM262845    KM102979    KX354450    AIY22226.1    AIY22385.1    AJZ77121.1    AOO54362.1    Z19544    U18466    AP012217    BAO40880.1    HE580270    CCD24456.1    FN392321    CAY70299.1    FR839630    CCA39907.1    LT598472    SCU86869.1    HE612861    CCE63831.1    CCAG010022297    CP014584    ANZ74196.1    GAMC01004884    JAC01672.1    UFAJ01000041    SSD58725.1    CU928167    CAR21909.1    KV454483    ODV60045.1    DS480420    EDO16637.1    KV454426    ODQ82731.1    LS990928    VAX57769.1    CR380954    CAG59814.1    CP014246    AMD21587.1    LLZZ01000149    KTA99005.1    LT635768    SGZ56927.1    LT635761    SGZ57480.1    LT598456    SCU79705.1    BDGX01000026    GAV50762.1    CU928179    CAR29263.1    HE616747    CCE92867.1    CP019494    AQZ12716.1    HG316455    CDF88667.1    FUGC01000001    SJM82510.1    AGBW02013517    OWR43287.1    HE806324    CCH62687.1    BDGX01000048    GAV55553.1    NETL01000028    OTN64207.1    AM910996    CWHQ02000019    CWHR02000022    CAQ42467.1    SBO26419.1    SBO28983.1    GL996527    EGV62384.1    OUUW01000001    SPP73583.1    PKFO01000010    PVH23158.1    HE576758    CCC71226.1    CP001669    AFZ79185.1    LN736366    CEP63172.1    LT598482    SCU86109.1    DS989737    EEA08145.1    CP019501    AQZ16953.1   

Proteomes

UP000101566    UP000105860    UP000000861    UP000000858    UP000141072    UP000241813    + More
UP000000859    UP000000860    UP000130745    UP000101090    UP000108903    UP000110401    UP000117635    UP000142390    UP000266411    UP000000624    UP000065495    UP000000689    UP000000314    UP000006853    UP000190866    UP000005666    UP000092444    UP000094565    UP000092443    UP000002036    UP000095038    UP000000267    UP000094336    UP000002428    UP000243052    UP000054886    UP000182259    UP000182334    UP000190274    UP000187013    UP000008536    UP000005627    UP000190375    UP000019375    UP000196771    UP000007151    UP000002866    UP000031513    UP000192221    UP000000707    UP000244309    UP000001640    UP000031512    UP000054304    UP000191144    UP000001460   

PRIDE

P0C8G2    P0C8G1    P0C8G0    P42490   

Pfam

PF02223   Thymidylate_kin

Interpro

IPR018095   Thymidylate_kin_CS
IPR039430   Thymidylate_kin_like_dom
IPR027417   P-loop_NTPase
IPR018094   Thymidylate_kinase

SUPFAM

SSF52540   SSF52540

ProteinModelPortal

A0A0C5AZW1   A0A2Z5DGC8   A0A0C5AZC7   P0C8F9   P0C8G2   E0WMH3   + More
A0A2X0RUU2   A0A0N6WHZ1   P0C8G1   P0C8G0   A9JKX1   D4I5M3   A9JLM6   A0A0A1E300   P42490   W0TBV7   G0W9J5   C4R413   F2QWX9   A0A1G4JA25   G8BUP5   A0A1B0G795   A0A1B2J889   W8C5G7   A0A1A9XUE6   A0A376B211   C5DDP8   A0A1D2VEJ9   A7TM70   A0A1E3QYN2   A0A3F2Y7Z2   Q6FSB3   A0A120K2I1   A0A0W0CHT6   A0A1L0BZZ3   A0A1L0DNP7   A0A1G4ISA8   A0A1Q3A4X7   C5DZH9   G8ZW73   A0A1S7HID8   S6E0Z3   A0A212M3W0   A0A212EPA4   I2H8I5   A0A1Q3AJ63   A0A1Y3DNB9   A0A384L2E6   A0A1W4VCF3   G3B8F2   A0A3B0J316   A0A2V1AZ45   G0VIJ1   L0AUF2   A0A0C7MZG8   A0A1G4J8U9   B6AIV4   A0A1S7HVA4  

PDB

1E9F     E-value=3.06859e-12,     Score=171