ASFVdb The African Swine Fever Virus Database
Strain
Uganda_N10_2015 (Region: Uganda, Tororo district;  Strain: N10;  Date: 2015)
Gene
p110-13L
Description
Annotated in NCBI,  Member of multigene family 110 (Lis117)
GenBank Accession
Full name
Protein LIS 117       + More
Protein MGF 110-13L      
Protein MGF 110-11L      
Protein LIS 119-1      
Protein MGF 360-3L      
Protein MGF 360-1L      
Protein MGF 110-9L      
Protein LIS 290      
Protein MGF 110-4L      
Protein MGF 110-1L      
Protein LIS 124-2      
Protein LIS 124-1      
Protein MGF 110-3L      
 

Sequence

CDS
ATGAAAGTATTCGCTCTTTTGAGTATTTTGGTTTGGTTAGCCCAACCAGTTTTAAACCGACCCCTTTCCATCTTTTATACGAAACAAATTTTACCAAGAACCTATACACCTCCCATGAGAGAACTTGAATATTGGTGTACGTATGGAAAACACTGTGATTTCTGCTGGACATGTAAGAATGGTATTTGTAAAAATAAGGTTTTGGATGATATGCCTCTTATTGTTCAAAATGATTACATCAGTAAATGTAGTATTACCCGTTTTATTGATCGTTGTATGTACTTTATTGAGCCTAAAATACCGTATATTCATTACATGAATTGTACTCTGCCCACATATTTTAGTTAA
Protein
MKVFALLSILVWLAQPVLNRPLSIFYTKQILPRTYTPPMRELEYWCTYGKHCDFCWTCKNGICKNKVLDDMPLIVQNDYISKCSITRFIDRCMYFIEPKIPYIHYMNCTLPTYFS

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Causes the redistribution of lumenal ER protein to an enlarged ERGIC compartment.
Similarity
Belongs to the asfaviruses V110 family.
Belongs to the asfivirus MGF 110 family.
Keywords
Early protein   Signal   Complete proteome   Host membrane   Membrane   Transmembrane   Transmembrane helix   Glycoprotein   Repeat   Virion   Reference proteome  
Feature
chain  Protein LIS 117
EMBL
MH025916    MH025917    MH025918    MH025919    MH025920    AXB49239.1    + More
AXB49413.1    AXB49585.1    AXB49758.1    AXB49929.1    KM111295    AJL34189.1    M58155    KM111294    AJL34026.1    AY261361    AM712239    CAN10107.1    KM262844    AIY22199.1    KM102979    AJZ77135.1    KX354450    AOO54322.1    MG939584    AXZ95940.1    FR682468    CBW46668.1    MG939583    AXZ95787.1    AOO54321.1    AY261366    AJL34023.1    AXB49236.1    AXB49410.1    AXB49755.1    AXB49926.1    CBW46664.1    MG939586    MG939587    MG939588    AXZ95784.1    AXZ95937.1    AXZ95964.1    AXZ95981.1    AXZ96076.1    AJL34186.1    AM712240    CAN10364.1    KM262845    AIY22366.1    AXB49583.1    AIY22367.1    AY261360    AY261363    FN557520    CBH29106.1    AOO54318.1    CAN10105.1    AIY22196.1    AJZ77108.1    AJL34022.1    CBW46662.1    AXZ95782.1    AXZ95962.1    AXZ95979.1    AXZ96074.1    AJL34185.1    AXB49235.1    AXB49409.1    AXB49582.1    AXB49754.1    AXB49925.1    AJL34177.1    AXB49226.1    AXB49399.1    AXB49573.1    AXB49916.1    AXB49745.1    KP055815    AKO62692.1    M36467    U18466    CBW46653.1    AXZ95776.1    AXZ95956.1    AXZ95973.1    AXZ96068.1    AJL34015.1    CAN10104.1    CBH29105.1    AJZ77110.1    AKO62690.1    AOO54316.1    AIY22195.1    AIY22358.1    CBW46655.1    AXZ95777.1    AXZ95957.1    AXZ95974.1    AXZ96069.1    CAN10359.1    AIY22361.1    AJL34012.1    CAN10356.1    CAN10358.1    U81365    AAC40560.1    AIY22360.1    AJL34014.1    AJL34180.1    AXB49229.1    AXB49402.1    AXB49576.1    AXB49748.1    AXB49919.1    AJL34179.1    AXB49228.1    AXB49401.1    AXB49575.1    AXB49747.1    AXB49918.1    AJL34178.1   
Pfam
PF01639   v110
Interpro
IPR004848   V110_vir
PDB
6NNF     E-value=2.9848,     Score=66

Ontologies

KEGG

Subcellular Location

From MSLVP
Multi-Pass Membrane
From Uniprot
Host membrane  
Virion  
Host endoplasmic reticulum-Golgi intermediate compartment  
Membrane  

Topology

Length:
115
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
1.49439
Exp number, first 60 AAs:
1.47848
Total prob of N-in:
0.05011
outside
1  -  115
 
 

Population Genetic Test Statistics

Pi
0.0826745
Theta
0.2201681
Tajima's D
-2.1924668
CLR
147.25823
Interpretation
Possibly Positive selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971    
China_AnhuiXCGQ_2018 Protein
AJZ77135.1
China_ASFV-SY18_2018 Protein
CAN10107.1
Poland_Pol16_20186_o7_2016-2017 Protein
AJZ77135.1
Poland_Pol16_20538_o9_2016-2017 Protein
AJZ77135.1
Poland_Pol16_20540_o10_2016-2017 Protein
AJZ77135.1
Poland_Pol16_29413_o23_2016-2017 Protein
AJZ77135.1
Poland_Pol17_03029_C201_2016-2017 Protein
AJZ77135.1
Poland_Pol17_04461_C210_2016-2017 Protein
AJZ77135.1
Poland_Pol17_05838_C220_2016-2017 Protein
AJZ77135.1
Poland_ASFV_POL_Podlaskie_2015 Protein
AJZ77135.1
Uganda_R8_2015 Protein
AXB49239.1
Uganda_R7_2015 Protein
AXB49413.1
Uganda_R25_2015 Protein
AXB49585.1
Uganda_N10_2015 Protein
AXB49758.1
Uganda_R35_2015 Protein
AXB49929.1
Estonia_2014    
Italy_26544_OG10_2010 Protein
Protein
AJZ77135.1
AJZ77135.1
Italy_47_Ss_2008_2008 Protein
Protein
AOO54321.1
AOO54322.1
Portugal_OURT_88.3_1988    
Spain_E75_1975 Protein
AJZ77135.1
Russia_Georgia_2007 Protein
AJZ77135.1
Kenya_Tk1_2005 Protein
AJZ77135.1
Kenya_Bus_2006 Protein
AJL34189.1
Russia_Odintsovo_2014 Protein
AJZ77135.1
Portugal_L60_1960 Protein
AIY22199.1
Portugal_NHV_1968    
Russia_Kashino_2013 Protein
AJZ77135.1
Benin_1997 Protein
CAN10107.1
South_Africa_KNP_Pretorisuskop_1996    
South_Africa_MGR_Mkuzi_1979 Protein
AJZ77135.1
Malawi_Lil_1983 Protein
AJZ77135.1
Kenya_1950 Protein
AJZ77135.1
Namibia_Warthog_1980 Protein
AJZ77135.1
South_Africa_Warmbaths_1987 Protein
AJZ77135.1
Malawi_Tengani_1962    
China_HLJ_2018 Protein
AJZ77135.1
China_LN_2018 Protein
AJZ77135.1
China_wbBS01_2018 Protein
AJZ77135.1
Ukraine_Kyiv_2014 Protein
AJZ77135.1
Belgium_Etalle_wb_2018 Protein
AJZ77135.1
Lithuania_LT14_2014 Protein
QEY87807.1
South_Africa_1985 Protein
AJZ77135.1
South_Africa_2_2008    
Zambia_LIV_1983 Protein
AJZ77135.1
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