ASFVdb The African Swine Fever Virus Database
Strain
Portugal_L60_1960 (Region: Portugal;  Strain: L60;  Date: 1960)
Gene
pMGF 110-13L
Description
Annotated in NCBI,  Benin 97-1
GenBank Accession
Full name
Protein MGF 110-13L       + More
Protein MGF 110-11L      
Protein MGF 360-1L      
Protein MGF 360-3L      
 

Sequence

CDS
ATGGGGGGGGGTGACCATCAACAATTATCTATAAAGCAATACTGTCTCTATTTCATCATTGGTATTGCTTATACAGGCTGCTTTGTATGTGCGCTTTGTAAGAATCTGCGTCTGAGTACAACTATGAAACTTTTCGTTCTTTTGAGTATTTTGGTTTGGTTAGCACAGCCAGTTTTAAATCGACCCCTTTCCATCTTTTATACGAAACAAATTTTACCAAGGACCTATACGCCTCCTATGAGAGAACTTGAATATTGGTGTACGTATGGAAAACACTGTGATTTCTGCTGGGATTGTAAGAATGGTATTTGTAAAAATAAGGTTTTGGATAATATGCCTCTTATTGTTCAAAATGATTATATCAGTAAATGTAGTATTACCCGTTTTATTGATCGTTGTATGTACTTTATTGAGCCTAAAATACCATATATTCATTATATGAATTGCTCTCTGCCCCACATATTTTCGTTAATATAA
Protein
MGGGDHQQLSIKQYCLYFIIGIAYTGCFVCALCKNLRLSTTMKLFVLLSILVWLAQPVLNRPLSIFYTKQILPRTYTPPMRELEYWCTYGKHCDFCWDCKNGICKNKVLDNMPLIVQNDYISKCSITRFIDRCMYFIEPKIPYIHYMNCSLPHIFSLI

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Similarity
Belongs to the asfivirus MGF 110 family.
Keywords
Complete proteome   Host membrane   Membrane   Transmembrane   Transmembrane helix   Glycoprotein  
Feature
chain  Protein MGF 110-13L
Pfam
PF01639   v110
Interpro
IPR004848   V110_vir
PDB
6NNF     E-value=2.9848,     Score=66

Ontologies

Subcellular Location

From MSLVP
Multi-Pass Membrane
From Uniprot
Host membrane  

Topology

Length:
158
Number of predicted TMHs:
2
Exp number of AAs in TMHs:
39.9594
Exp number, first 60 AAs:
36.59164
Total prob of N-in:
0.02262
POSSIBLE N-term signal
sequence
outside
1  -  9
TMhelix
10  -  32
inside
33  -  43
TMhelix
44  -  66
outside
67  -  158
 
 

Population Genetic Test Statistics

Pi
0.0975787
Theta
0.2482364
Tajima's D
-2.1297203
CLR
3.500199
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971    
China_AnhuiXCGQ_2018 Protein
AJZ77135.1
China_ASFV-SY18_2018 Protein
CAN10107.1
Poland_Pol16_20186_o7_2016-2017 Protein
AJZ77135.1
Poland_Pol16_20538_o9_2016-2017 Protein
AJZ77135.1
Poland_Pol16_20540_o10_2016-2017 Protein
AJZ77135.1
Poland_Pol16_29413_o23_2016-2017 Protein
AJZ77135.1
Poland_Pol17_03029_C201_2016-2017 Protein
AJZ77135.1
Poland_Pol17_04461_C210_2016-2017 Protein
AJZ77135.1
Poland_Pol17_05838_C220_2016-2017 Protein
AJZ77135.1
Poland_ASFV_POL_Podlaskie_2015 Protein
AJZ77135.1
Uganda_R8_2015 Protein
AXB49239.1
Uganda_R7_2015 Protein
AXB49413.1
Uganda_R25_2015 Protein
AXB49585.1
Uganda_N10_2015 Protein
AXB49758.1
Uganda_R35_2015 Protein
AXB49929.1
Estonia_2014    
Italy_26544_OG10_2010 Protein
Protein
AJZ77135.1
AJZ77135.1
Italy_47_Ss_2008_2008 Protein
Protein
AOO54321.1
AOO54322.1
Portugal_OURT_88.3_1988    
Spain_E75_1975 Protein
AJZ77135.1
Russia_Georgia_2007 Protein
AJZ77135.1
Kenya_Tk1_2005 Protein
AJZ77135.1
Kenya_Bus_2006 Protein
AJL34189.1
Russia_Odintsovo_2014 Protein
AJZ77135.1
Portugal_L60_1960 Protein
AIY22199.1
Portugal_NHV_1968    
Russia_Kashino_2013 Protein
AJZ77135.1
Benin_1997 Protein
CAN10107.1
South_Africa_KNP_Pretorisuskop_1996    
South_Africa_MGR_Mkuzi_1979 Protein
AJZ77135.1
Malawi_Lil_1983 Protein
AJZ77135.1
Kenya_1950 Protein
AJZ77135.1
Namibia_Warthog_1980 Protein
AJZ77135.1
South_Africa_Warmbaths_1987 Protein
AJZ77135.1
Malawi_Tengani_1962    
China_HLJ_2018 Protein
AJZ77135.1
China_LN_2018 Protein
AJZ77135.1
China_wbBS01_2018 Protein
AJZ77135.1
Ukraine_Kyiv_2014 Protein
AJZ77135.1
Belgium_Etalle_wb_2018 Protein
AJZ77135.1
Lithuania_LT14_2014 Protein
QEY87807.1
South_Africa_1985 Protein
AJZ77135.1
South_Africa_2_2008    
Zambia_LIV_1983 Protein
AJZ77135.1
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