Strain

Portugal_NHV_1968 (Region: Portugal; Strain: NHV; Date: 1968)

Gene

structural Protein P22

Description

Annotated in NCBI, member of multigene family p22

Location

KM262845.1(+):3000-3533

GenBank Accession

AIY22354.1

Full name

Envelope protein p22

Sequence

CDS

ATGTTTAATATTAAAATGACAATTTCTACATTGCTTATTGCTCTTATTATACTAGTTATTATTATTTTAGTCGTATTTTTATATTATAAAAAACAACAACCACCAAAAAAGGTCTGTAAAGTAGATAAAGATTGTGGTAGTGGAGAGCATTGTGTTCGTGGAACATGCAGCACATTGAGCTGCTTAGACGCTGTAAAAATGGACAAACGAAATATTAAGATAGATTCTAAGATTTCCTCATGTGAATTCACTCCCAATTTTTACCGTTTTACGGATACTGCTGCCGATGAGCAGCAAGAATTTGGAAAAACACGGCATCCTATAAAAATAACTCCATCTCCAAGTGAATCCCATAGCCCCCAAGAGGTGTGTGAAAAATATTGTTCATGGGGAACCGATGACTGTACAGGTTGGGAATATGTTGGTGATGAAAAGGAGGGAACATGTTATGTATATAATAATCCACATCACCCGGTTCTTAAATATGGTAAGGATCACATCATAGCCTTACCTAGAAATCATAAACATGCATAA

Protein

MFNIKMTISTLLIALIILVIIILVVFLYYKKQQPPKKVCKVDKDCGSGEHCVRGTCSTLSCLDAVKMDKRNIKIDSKISSCEFTPNFYRFTDTAADEQQEFGKTRHPIKITPSPSESHSPQEVCEKYCSWGTDDCTGWEYVGDEKEGTCYVYNNPHHPVLKYGKDHIIALPRNHKHA

Summary

Similarity

Belongs to the asfivirus envelope protein p22 family.

Keywords

Complete proteome Early protein Host cell membrane Host membrane Membrane Reference proteome Transmembrane Transmembrane helix Virion

Feature

chain Envelope protein p22

Uniprot

A9JKR0 D4I5I8 A9JLH5 A0A0A1E0I2 P23169 H9EJY2 + More
E0WMB7 X2L2S6 A0A0C5BC16 P0C9W2 P0C9W3 P0C9W0 A0A0C5BCG8 A0A2Z5DG81 A0A2Z5DG43

Pubmed

18198370 25406173 26618713 2325203 1994575 21470447 + More
25645905

EMBL

AM712239 CAN10100.1 FN557520 CBH29101.1 AM712240 CAN10352.1 + More
KM262844 KM262845 KM102979 KP055815 KX354450 KU641719 KU641720 KU641721 KU641722 KU641723 KU641724 KU641725 KU641726 KU641727 KU641728 KU641729 KU641730 KU641731 KU641733 KU641734 KU641735 KU641736 KU641737 KU641738 KU641739 KU641740 KU641741 KU641742 KU641743 KU641744 KU641745 KU641746 KU641747 KU641748 KU641749 AIY22191.1 AIY22354.1 AJZ77142.1 AKO62686.1 AOO54311.1 APF30089.1 APF30090.1 APF30091.1 APF30092.1 APF30093.1 APF30094.1 APF30095.1 APF30096.1 APF30097.1 APF30098.1 APF30099.1 APF30100.1 APF30101.1 APF30103.1 APF30104.1 APF30105.1 APF30106.1 APF30107.1 APF30108.1 APF30109.1 APF30110.1 APF30111.1 APF30112.1 APF30113.1 APF30114.1 APF30115.1 APF30116.1 APF30117.1 APF30118.1 APF30119.1 U18466 M57546 JQ771687 JQ771688 JQ771689 JQ771690 JQ771691 JQ771692 MG939583 MG939585 MG939586 MG939587 MG939588 MG939589 AFD34349.1 AFD34350.1 AFD34351.1 AFD34352.1 AFD34353.1 AFD34354.1 AXZ95770.1 AXZ95948.1 AXZ95950.1 AXZ95967.1 AXZ96062.1 AXZ96222.1 FR682468 CBW46645.1 KJ380912 AHN94309.1 KM111294 AJL34008.1 AY261363 AY261366 AY261360 KM111295 AJL34173.1 MH025919 AXB49741.1 MH025916 MH025917 MH025918 MH025920 AXB49222.1 AXB49395.1 AXB49569.1 AXB49912.1

Proteomes

UP000130745 UP000101090 UP000108903 UP000110401 UP000117635 UP000142390 + More
UP000241813 UP000266411 UP000000624 UP000141072 UP000105860 UP000000859 UP000000858 UP000000861 UP000101566

PRIDE

P0C9W2 P0C9W3 P0C9W0

ProteinModelPortal

A9JKR0 D4I5I8 A9JLH5 A0A0A1E0I2 P23169 H9EJY2 + More
E0WMB7 X2L2S6 A0A0C5BC16 P0C9W2 P0C9W3 P0C9W0 A0A0C5BCG8 A0A2Z5DG81 A0A2Z5DG43

Ontologies

KEGG

vg:22220394

GO:0016021  C:integral component of membrane
GO:0055036  C:virion membrane
GO:0020002  C:host cell plasma membrane

Subcellular Location

From MSLVP

Single-Pass Membrane

From Uniprot

Virion membrane
Host cell membrane

Topology

Length:

177

Number of predicted TMHs:

Exp number of AAs in TMHs:

21.92632

Exp number, first 60 AAs:

21.92626

Total prob of N-in:

0.45033

POSSIBLE N-term signal

sequence

inside

1 - 6

TMhelix

7 - 29

outside

30 - 177

Population Genetic Test Statistics

0.0625869

Theta

0.1228974

Tajima's D

-1.7049586

CLR

1.989007

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein	AKO62686.1
China_AnhuiXCGQ_2018	Protein	AYW33955.1
China_ASFV-SY18_2018	Protein	AKO62686.1
Poland_Pol16_20186_o7_2016-2017	Protein	AXZ95770.1
Poland_Pol16_20538_o9_2016-2017	Protein	CBW46645.1
Poland_Pol16_20540_o10_2016-2017	Protein	AXZ95948.1
Poland_Pol16_29413_o23_2016-2017	Protein	AXZ95950.1
Poland_Pol17_03029_C201_2016-2017	Protein	AXZ95967.1
Poland_Pol17_04461_C210_2016-2017	Protein	AXZ96062.1
Poland_Pol17_05838_C220_2016-2017	Protein	AXZ96222.1
Poland_ASFV_POL_Podlaskie_2015	Protein	CBW46645.1
Uganda_R8_2015	Protein	AXB49222.1
Uganda_R7_2015	Protein	AXB49395.1
Uganda_R25_2015	Protein	AXB49569.1
Uganda_N10_2015	Protein	AXB49741.1
Uganda_R35_2015	Protein	AXB49912.1
Estonia_2014
Italy_26544_OG10_2010	Protein	AJZ77142.1
Italy_47_Ss_2008_2008	Protein	AOO54311.1
Portugal_OURT_88.3_1988	Protein	CAN10352.1
Spain_E75_1975	Protein	CBH29101.1
Russia_Georgia_2007	Protein Protein	CBW46645.1 CBW46645.1
Kenya_Tk1_2005	Protein	AJL34008.1
Kenya_Bus_2006	Protein	AJL34173.1
Russia_Odintsovo_2014	Protein	CBW46645.1
Portugal_L60_1960	Protein	AIY22191.1
Portugal_NHV_1968	Protein	AIY22354.1
Russia_Kashino_2013	Protein	CBW46645.1
Benin_1997	Protein	CAN10100.1
South_Africa_KNP_Pretorisuskop_1996	Protein	CBW46645.1
South_Africa_MGR_Mkuzi_1979	Protein	CBW46645.1
Malawi_Lil_1983	Protein	CBW46645.1
Kenya_1950	Protein	CBW46645.1
Namibia_Warthog_1980	Protein	CBW46645.1
South_Africa_Warmbaths_1987	Protein	CBW46645.1
Malawi_Tengani_1962	Protein	CBW46645.1
China_HLJ_2018	Protein	QBH90468.1
China_LN_2018	Protein	QBH90653.1
China_wbBS01_2018	Protein Protein	CBW46645.1 QDL88012.1
Ukraine_Kyiv_2014	Protein	QED21542.1
Belgium_Etalle_wb_2018	Protein	QED90426.1
Lithuania_LT14_2014	Protein	QEY87785.1
South_Africa_1985
South_Africa_2_2008
Zambia_LIV_1983