Strain

Portugal_L60_1960 (Region: Portugal; Strain: L60; Date: 1960)

Gene

pMGF 505-10R

Description

Annotated in NCBI, CBH29133.1

Location

KM262844.1(+):39060-40688

GenBank Accession

AIY22223.1

Full name

Protein MGF 505-10R       + More
Protein MGF 505-2R
Protein MGF 505-5R
Protein MGF 505-7R
Protein MGF 505-6R
Protein MGF 505-4R
Protein MGF 505-9R
Protein MGF 505-1R

Sequence

CDS

ATGTTCTCCCTTCAGGAGCTCTGCCGGAAGAACATTTACATTCTTCCTTACCCCTTGGGTAAGCATGTACTTCAACAACTAGGGCTGTACTGGAAGGGACATGGATCTCTTCAACGAATCGGAGATGACCATGTACTCTTACAACAGGACCTGATCTTTTCCATCAACGAGGCCTTAAGAATGGCGGCAGAAGAAGGAAACAATGAAGTAGTAAAGCTCTTGTTACTGTGGGAGGGAAACCTTCATTATGCCATCATAGGAGCTTTAGAGGGCGACCGATACGACCTTATCCATAAATATTATGAACAAATTGGGGACTGCCACAAGATTCTTCCTTTAATCCAAGACCCGCAAATCTTTGAAAAATGCCATGAATTGAGTAACTCCTGTAACATTCGATGCCTTTTAGAACATGCAGTAAAACACAACATGCTTTCTATTCTTCAAAAACATAAGGATCAAATAAGATTACACATGGCATTAACCCAAATACTATTTGAATTGGCGTGCCATGAACGTAAGAATGACATCATTAGATGGATCGGTTATTCCCTGCACATATACCATCTAGAGACTATTTTTGATGTTGCATTCGCCCATAAAAATTTATCCTTATACGTTTTAGGGTATGAACTTCTCATGCACAAAGTAAATACAGAGGCTGCAAATATAGATTTACCCAATTTGCTATCATATCACCTTCGAACTGCGGCGGCAGGAGGTCTTCTTAATTTTATGTTAGAAACAATAAAGCATGGTGGGTGTGTGGATAAAACCGTTCTATCCGCGGCTATCAGGTACAAGCATAGGAAAATTGTGGCTCATTTTATTCATCAGGTTCCCCGTAAAACCGTTAAAAAACTGCTACTCTATGCTGTGCAGGCTCGGGCCCCCAAAAAAACACTAAATCTACTTTTATCTTCCTTAAACTATGCCGTGCACACCATCACCAAACAACTCGTACACAATGTCATCAACTACAGTTCCACGCTTGTCGTAAAGCTTTTACTCATGCGGCGAAAAAGGAAGTTAAACCTAGTAGATGCCGTTTTAGCCAGACTTGTAAAATATTCCACCTATACAGACATTGTACAATTCATGGGTGAGTTTTCTGTGAGCCCAGAAAGGGTGATCAAAATGGCTGCACGGGAATCCAGGACCTTTCTGATTGAAATGATCTCCAAAGCTGCTTGGGGAAATCACCCACAGACGTTGATTCATCATCTCAAACACCTAACCAATACCATGAAGCCTCAATCTGGAAAAGACCTCATCATATATACCATCCACTATATTTATCTAAACTCTAATATGCTGGTAGCGGAGGAGGAAAAAAATATTTTTAAATTAGCAAAATTTTATGCGAATCATAACGCGGTAAACAGGTTTAAACAAATTTGTGAAGACTATTATATATTAGATGCACGATTTAAAACACTTATTTTAGAATGTTTTGAAATTGCCGTCCAGAAAAACTATCCTAGAATTGCAAATATTGTGGATGACTATATTCGATTCCTTTTTTACAGGGGAAATATAACCGAGGAAGAAATTCGTGAAGCCTATTCTTTAAAAGATGCTGAGGTTTATGTAGATTTAAAATGGTTACAACAAGGAGAAATGGTTTAA

Protein

MFSLQELCRKNIYILPYPLGKHVLQQLGLYWKGHGSLQRIGDDHVLLQQDLIFSINEALRMAAEEGNNEVVKLLLLWEGNLHYAIIGALEGDRYDLIHKYYEQIGDCHKILPLIQDPQIFEKCHELSNSCNIRCLLEHAVKHNMLSILQKHKDQIRLHMALTQILFELACHERKNDIIRWIGYSLHIYHLETIFDVAFAHKNLSLYVLGYELLMHKVNTEAANIDLPNLLSYHLRTAAAGGLLNFMLETIKHGGCVDKTVLSAAIRYKHRKIVAHFIHQVPRKTVKKLLLYAVQARAPKKTLNLLLSSLNYAVHTITKQLVHNVINYSSTLVVKLLLMRRKRKLNLVDAVLARLVKYSTYTDIVQFMGEFSVSPERVIKMAARESRTFLIEMISKAAWGNHPQTLIHHLKHLTNTMKPQSGKDLIIYTIHYIYLNSNMLVAEEEKNIFKLAKFYANHNAVNRFKQICEDYYILDARFKTLILECFEIAVQKNYPRIANIVDDYIRFLFYRGNITEEEIREAYSLKDAEVYVDLKWLQQGEMV

Summary

Function

Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.

Similarity

Belongs to the asfivirus MGF 505 family.

Keywords

Complete proteome Reference proteome ANK repeat Repeat

Feature

chain Protein MGF 505-10R

Uniprot

D4I5M0 A0A1C6ZXX4 A9JLM1 A0A0A1DY08 A9JKW5 A0A0A1E0I6 + More
Q89869 P0C9V2 P0C9V1 E0WMG9 A0A2X0TKE5 Q65114 A0A0C5AYV0 A0A0C5AZ79 P0C9V0 A0A2Z5DF55 Q65128 P0C9T6 P0C9S9 A9JKV3 A0A0A1E2Z4 E0WMG1 A0A2X0RU65 A0A0C5B2F7 Q89702 A0A2Z5DEX1 D4I5L3 A0A0C5AWL2 P0C9S8 P0C9S7 E0WMG5 A0A2X0TC45 A0A385KLZ1 A9JLL5 A0A0A1E0Y6 A9JKV8 D4I5L6 A0A0A1E043 Q89777 P0C9T8 P0C9T9 P0C9T7 A0A0C5B227 A0A0C5AW92 E0WMG7 A0A2X0RTS3 P0C9U5 P0C9U4 D4I5L7 A9JLL7 A0A0A1E0L2 A9JKW0 Q89925 A0A3G1EUV7 A0A0N7CQW3 A9JKW2 A0A0A1E2Z7 D4I5L8 E0WMG6 A0A2X0S742 P0C9U0 P0C9U3 P0C9U1 A9JLL8 A0A0A1DY94 A0A0C5BC47 P0C9U2 A0A0C5AZC1 P0C9T2 A9JKV6 D4I5L5 A9JLL3 A0A0A1E0I1 Q89768 P0C9U7 A0A0C5B2G2 A0A0C5B231 P0C9T3 A0A2Z5DFS5 A0A0C5AZV5 P0C9U6 E0WMG4 A0A2X0RVA3 A0A385KLZ6 A0A2Z5DEF5 A0A0C5BCK1 P0C9T5 P0C9U8 A9JKW3 D4I5L9 A9JLM0 A0A0A1DXI4 Q89740 E0WMG8 A0A2X0SDM0 P0C9T4 P0C9U9 P0C9S6 E0WMF6 A0A2X0RTR5

Pubmed

18198370 25406173 26618713 11831707 21470447 8030263 + More
25645905

EMBL

FN557520 CBH29133.1 KM102979 KX354450 AJZ77055.1 AOO54359.1 + More
AM712240 CAN10380.1 KM262845 AIY22382.1 AM712239 CAN10131.1 KM262844 KP055815 AIY22223.1 AKO62714.1 U02468 U18466 AY261366 AY261363 FR682468 CBW46697.1 MG939583 MG939587 MG939588 LS478113 AXZ95809.1 AXZ95997.1 AXZ96092.1 SPS73454.1 AY261361 U03761 KM111294 AJL34047.1 KM111295 AJL34212.1 AY261360 MH025916 MH025917 MH025918 MH025919 MH025920 AXB49261.1 AXB49435.1 AXB49607.1 AXB49778.1 AXB49951.1 U03762 CAN10124.1 AIY22216.1 AJZ77062.1 AKO62707.1 AOO54349.1 CBW46689.1 AXZ95802.1 AXZ95990.1 AXZ96085.1 SPS73446.1 AJL34206.1 AXB49255.1 AXB49429.1 AXB49601.1 AXB49773.1 AXB49945.1 CBH29126.1 AJL34209.1 AXB49258.1 AXB49432.1 AXB49604.1 AXB49775.1 AXB49948.1 CBW46693.1 SPS73450.1 AXZ95806.1 AXZ95994.1 AXZ96089.1 CAN10376.1 AIY22378.1 CAN10127.1 CBH29129.1 AIY22219.1 AJZ77066.1 AKO62710.1 AOO54354.1 AJL34041.1 AJL34044.1 CBW46695.1 SPS73452.1 CBH29130.1 CAN10377.1 AIY22220.1 AIY22379.1 AJZ77060.1 AKO62711.1 AOO54355.1 CAN10128.1 AOO54356.1 AKO62712.1 CAN10129.1 AIY22221.1 AJZ77061.1 CBH29131.1 CBW46694.1 AXZ95807.1 AXZ95995.1 AXZ96090.1 SPS73451.1 CAN10378.1 AIY22380.1 AJL34043.1 AJL34045.1 CAN10126.1 CBH29128.1 CAN10375.1 AIY22218.1 AIY22377.1 AJZ77065.1 AKO62709.1 AOO54353.1 AJL34211.1 AXB49260.1 AXB49434.1 AXB49606.1 AXB49777.1 AXB49950.1 AJL34046.1 AXB49259.1 AXB49433.1 AXB49605.1 AXB49776.1 AXB49949.1 AJL34210.1 CBW46692.1 AXZ95993.1 AXZ96088.1 SPS73449.1 AXZ95805.1 AXB49257.1 AXB49431.1 AXB49603.1 AXB49947.1 AJL34208.1 CAN10130.1 CBH29132.1 CAN10379.1 AIY22222.1 AIY22381.1 AJZ77064.1 AKO62713.1 AOO54358.1 CBW46696.1 AXZ95808.1 AXZ95996.1 AXZ96091.1 SPS73453.1 CBW46685.1 AXZ95798.1 AXZ95986.1 AXZ96081.1 SPS73442.1

Proteomes

UP000101090 UP000117635 UP000266411 UP000108903 UP000110401 UP000130745 + More
UP000142390 UP000241813 UP000000624 UP000000858 UP000000859 UP000141072 UP000000860 UP000105860 UP000101566 UP000000861

PRIDE

P0C9V2 P0C9V1 Q65114 P0C9V0 Q65128 Q89702 + More
P0C9S7 P0C9U5 P0C9U4 Q89925 P0C9U0 P0C9U2 P0C9U6 P0C9S6

Pfam

PF03158 DUF249

Interpro

IPR004858 MGF_505
IPR036770 Ankyrin_rpt-contain_sf

SUPFAM

SSF48403 SSF48403

Gene 3D

1.25.40.20

ProteinModelPortal

Ontologies

KEGG

vg:22220414 vg:22220408 vg:22220411 vg:22220412 vg:22220410 vg:22220413

Subcellular Location

From MSLVP

Nucleus

Topology

Length:

542

Number of predicted TMHs:

Exp number of AAs in TMHs:

0.12173

Exp number, first 60 AAs:

0.01855

Total prob of N-in:

0.00414

outside

1 - 542

Population Genetic Test Statistics

0.0457812

Theta

0.0546126

Tajima's D

-0.5561696

CLR

0.000096

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein	AKO62714.1
China_AnhuiXCGQ_2018	Protein	AYW34003.1
China_ASFV-SY18_2018	Protein Protein	CBH29133.1 AKO62714.1
Poland_Pol16_20186_o7_2016-2017	Protein	AXZ95809.1
Poland_Pol16_20538_o9_2016-2017
Poland_Pol16_20540_o10_2016-2017
Poland_Pol16_29413_o23_2016-2017
Poland_Pol17_03029_C201_2016-2017	Protein	AXZ95997.1
Poland_Pol17_04461_C210_2016-2017	Protein	AXZ96092.1
Poland_Pol17_05838_C220_2016-2017
Poland_ASFV_POL_Podlaskie_2015
Uganda_R8_2015	Protein	AXB49261.1
Uganda_R7_2015	Protein	AXB49435.1
Uganda_R25_2015	Protein	AXB49607.1
Uganda_N10_2015	Protein	AXB49778.1
Uganda_R35_2015	Protein	AXB49951.1
Estonia_2014	Protein	SPS73454.1
Italy_26544_OG10_2010	Protein	AJZ77055.1
Italy_47_Ss_2008_2008	Protein	AOO54359.1
Portugal_OURT_88.3_1988	Protein	CAN10380.1
Spain_E75_1975	Protein	CBH29133.1
Russia_Georgia_2007	Protein	CBW46697.1
Kenya_Tk1_2005	Protein	AJL34047.1
Kenya_Bus_2006	Protein	AJL34212.1
Russia_Odintsovo_2014
Portugal_L60_1960	Protein	AIY22223.1
Portugal_NHV_1968	Protein	AIY22382.1
Russia_Kashino_2013
Benin_1997	Protein	CAN10131.1
South_Africa_KNP_Pretorisuskop_1996
South_Africa_MGR_Mkuzi_1979
Malawi_Lil_1983	Protein	QGM12821.1
Kenya_1950	Protein	QGM12821.1
Namibia_Warthog_1980
South_Africa_Warmbaths_1987
Malawi_Tengani_1962
China_HLJ_2018	Protein	QBH90519.1
China_LN_2018	Protein	QBH90704.1
China_wbBS01_2018	Protein	QDL88062.1
Ukraine_Kyiv_2014	Protein	QED21589.1
Belgium_Etalle_wb_2018	Protein	QED90474.1
Lithuania_LT14_2014	Protein	QEY87837.1
South_Africa_1985	Protein	QGM12895.1
South_Africa_2_2008	Protein Protein	QGM12821.1 QGM12821.1
Zambia_LIV_1983