ASFVdb The African Swine Fever Virus Database
Strain
South_Africa_Warmbaths_1987 (Region: South Africa, Warmbaths;  Strain: Warmbaths;  Date: 1987)
Gene
Helicase
Description
Annoated by sequence mapping,  Member of helicase superfamily II group including human ERCC-3, vaccinia A18R and bacteriophage T5 D10
GenBank Accession
Full name
Putative ATP-dependent RNA helicase QP509L      
 

Sequence

CDS
ATGGAGGCCATTATATCCTTTGCTGGAATAGGAATAAATTATAAGAGGCTACAAAGTAAATTACAACATGATTTCGGGCGCCTTCTTAAGGCGCTCACCGTTACGGCGCGGGCATTACCTGGGCAGCCAAAGCACATAGCCATAAGACAGGAAACTGCCTTCACGCTGCAGGGGGAATACATTTATTTTCCCATATTGCTGCGAAAGCAGTTTGAAATGTTTAACATGGTTTACACGGCGCGCCCCGTGTCGCTGCGGGCCCTCCCATGCGTTGAAACAGAATTTCCACTATTTAACTACCAGCAAGAAATGGTCGATAAGATTCATAAAAAGCTCCTGTCCCCCTATGGGCGCTTTTACCTACATCTAAATACCGGTTTGGGGAAAACGCGTATTGCGATCAGTATTATTCAAAAACTTTTGTACCCTACCCTAGTCATCGTGCCCACCAAGGCGATTCAAGTACAGTGGATCGACGAGCTAACATTGCTCCTGCCCCACCTACGTGTAGCTGCTTACAATAATGCAGCGTGCAAGAAAAAGGACATGACGAGTAAAGAGTACGACGTCATCGTGGGAATCATTAATACCCTGCGCAAGAAGCCTGAGCAGTTCTTTGAGCCCTTCGGTCTAGTCGTGTTAGATGAGGCACATGAATTACACTCGCCGGAAAATTACAAAATTTTTTGGAAAATACAACTGAGTCGGATATTAGGACTGTCCGCTACACCCCTGGACCGGCCCGATGGTATGGACAAGATTATTATTCACCATCTAGGACAGCCCCAGAGGACTGTAAGTCCCACCACAACCTTTTCCGGGTACGTGAGGGAAATCGAATATCAGGGACATCCTGACTTTGTCAGCCCTGTGTGTATTAATGAAAAGGTATCGGCCATTGCCACCATTGATAAACTACTTCAAGATCCTTCGCGTATACAGCTTGTCGTAAATGAGGCAAAGCGGCTTTACTCCCTGCATACCGCTGAACCTCACAAATGGGGGACCGATGAGCCGTATGGCATCATCATTTTCGTGGAATTTCGTAAACTTTTAGAAATTTTTTATCAGGCGCTTTCCAAAGAATTCAAAGATGTTCAAATTATCGTTCCGGAGGTGGCGCTCCTATGCGGCGGGGTTTCAAATACCGCTCTTTCTCAGGCACACAGCGCTTCCATTATCTTGCTGACCTATGGCTACGGGCGGAGAGGCATTTCCTTCAAGCATATGACATCGATCATCATGGCAACGCCCCGCAGAAACAACATGGAGCAAATCTTGGGACGTATTACCCGGCAGGGATCGGATGAAAAAAAGGTACGCATCGTCGTGGACATTAAAGATACACTAAGCCCGCTTTCTAGCCAGGTCTACGACAGGCACCGGATTTACAAGAAAAAGGGCTACCCCATTTTTAAGTGCAGCGCCAGTTATCAGCAGCCCTATTCTTCTAATGAAGTTTTAATATGGGATCCTTATAACGAGTCATGTCTTGCGTGCACAACAACACCTCCTTCCCCGTCCAAACAG
Protein
MEAIISFAGIGINYKRLQSKLQHDFGRLLKALTVTARALPGQPKHIAIRQETAFTLQGEYIYFPILLRKQFEMFNMVYTARPVSLRALPCVETEFPLFNYQQEMVDKIHKKLLSPYGRFYLHLNTGLGKTRIAISIIQKLLYPTLVIVPTKAIQVQWIDELTLLLPHLRVAAYNNAACKKKDMTSKEYDVIVGIINTLRKKPEQFFEPFGLVVLDEAHELHSPENYKIFWKIQLSRILGLSATPLDRPDGMDKIIIHHLGQPQRTVSPTTTFSGYVREIEYQGHPDFVSPVCINEKVSAIATIDKLLQDPSRIQLVVNEAKRLYSLHTAEPHKWGTDEPYGIIIFVEFRKLLEIFYQALSKEFKDVQIIVPEVALLCGGVSNTALSQAHSASIILLTYGYGRRGISFKHMTSIIMATPRRNNMEQILGRITRQGSDEKKVRIVVDIKDTLSPLSSQVYDRHRIYKKKGYPIFKCSASYQQPYSSNEVLIWDPYNESCLACTTTPPSPSKQ

Summary

Catalytic Activity
ATP + H2O = ADP + H(+) + phosphate
Similarity
Belongs to the DEAD box helicase family. DEAH subfamily.
Keywords
ATP-binding   Complete proteome   Helicase   Hydrolase   Nucleotide-binding   Reference proteome  
Feature
chain  Putative ATP-dependent RNA helicase QP509L
Pfam
PF04851   ResIII
Interpro
IPR027417   P-loop_NTPase
IPR006935   Helicase/UvrB_N
IPR014001   Helicase_ATP-bd
SUPFAM
SSF52540   SSF52540
PDB
2FWR     E-value=1.2205e-07,     Score=135

Ontologies

KEGG

Subcellular Location

From MSLVP
Capsid

Topology

Length:
510
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.08863
Exp number, first 60 AAs:
0.00167
Total prob of N-in:
0.00166
outside
1  -  510
 
 

Population Genetic Test Statistics

Pi
0.0258154
Theta
0.0364084
Tajima's D
-0.9085267
CLR
0.007012
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
AKO62803.1
China_AnhuiXCGQ_2018 Protein
AYW34093.1
China_ASFV-SY18_2018 Protein
AKO62803.1
Poland_Pol16_20186_o7_2016-2017 Protein
AXZ95895.1
Poland_Pol16_20538_o9_2016-2017 Protein
CAN10222.1
Poland_Pol16_20540_o10_2016-2017 Protein
CAN10222.1
Poland_Pol16_29413_o23_2016-2017 Protein
CAN10222.1
Poland_Pol17_03029_C201_2016-2017 Protein
CAN10222.1
Poland_Pol17_04461_C210_2016-2017 Protein
AXZ96178.1
Poland_Pol17_05838_C220_2016-2017 Protein
CAN10222.1
Poland_ASFV_POL_Podlaskie_2015 Protein
CAN10222.1
Uganda_R8_2015 Protein
AXB49351.1
Uganda_R7_2015 Protein
AXB49525.1
Uganda_R25_2015 Protein
AXB49697.1
Uganda_N10_2015 Protein
AXB49868.1
Uganda_R35_2015 Protein
AXB50041.1
Estonia_2014 Protein
SPS73545.1
Italy_26544_OG10_2010 Protein
AJZ77063.1
Italy_47_Ss_2008_2008 Protein
AOO54489.1
Portugal_OURT_88.3_1988 Protein
CAN10471.1
Spain_E75_1975 Protein
CBH29222.1
Russia_Georgia_2007 Protein
CBW46788.1
Kenya_Tk1_2005 Protein
AJL34135.1
Kenya_Bus_2006 Protein
AJL34300.1
Russia_Odintsovo_2014 Protein
CAN10222.1
Portugal_L60_1960 Protein
AIY22313.1
Portugal_NHV_1968 Protein
AIY22471.1
Russia_Kashino_2013 Protein
CAN10222.1
Benin_1997 Protein
Protein
CAN10222.1
CAN10222.1
South_Africa_KNP_Pretorisuskop_1996 Protein
CAN10222.1
South_Africa_MGR_Mkuzi_1979 Protein
CAN10222.1
Malawi_Lil_1983 Protein
CAN10222.1
Kenya_1950 Protein
CAN10222.1
Namibia_Warthog_1980 Protein
CAN10222.1
South_Africa_Warmbaths_1987 Protein
CAN10222.1
Malawi_Tengani_1962 Protein
CAN10222.1
China_HLJ_2018 Protein
QBH90610.1
China_LN_2018 Protein
QBH90795.1
China_wbBS01_2018 Protein
QDL88153.1
Ukraine_Kyiv_2014 Protein
Protein
QED21733.1
QED21734.1
Belgium_Etalle_wb_2018 Protein
QED90565.1
Lithuania_LT14_2014 Protein
QEY87928.1
South_Africa_1985 Protein
CAN10222.1
South_Africa_2_2008 Protein
CAN10222.1
Zambia_LIV_1983 Protein
CAN10222.1
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