ASFVdb The African Swine Fever Virus Database
Strain
Kenya_1950 (Region: Kenya ;  Strain: Kenya 1950;  Date: 1950)
Gene
Helicase
Description
Annoated by sequence mapping,  Member of helicase superfamily II group including vaccinia D11L and D6R, and ASFV pD1133L
GenBank Accession
Full name
Putative ATP-dependent RNA helicase Q706L      
 

Sequence

CDS
ATGTCTTGCGTCCACAACAACACCTCCTTCCCCGTCCAAATAGAAGCATACCTAAAAGAGGTATTTGAAAAGTATAAAGAGCTTCAGGAAAGCAAGGACACCTCACTCACTGCCCGCTTTGCACGAGCACTGAAATACTACCAATTTTTGATTTACACCGCCTTTTCGGATCCTAAGTTTGGGATAGGCCAGGGGGAAAACACACGGGGCCTCCTCATCTATCACCAGATGGGCATGGGCAAAACCATTTTGAGCCTTTCGCTTGCTATTTCACTTTCACATATTTACAACCCGATTCTAATTGCGCCCAAATCGTTACACTCAAACTTCCAACAGTCTTTGCTAAAGCTTATTAAACTTTTATATCCGGAAACTACGGATCCCTCCAAAGAGCTACAGAAAATCTCGCGGCGCTTTAGGTTTGTGTCTCTAGACGCTTACAACATGGGGCAGCAGATCATAAAGGCGGGAGGGTCCTTAAACGGATGCCTGCTCATCGTTGACGAGGCACACAACCTCTTTAGGGGAATAATCAATAGCGCCAATGATAAAACAAATGCCCGCCAGCTGTACAATAATATTATGCAAGCTAAAAATATTCGTATCTTGTTTTTAACAGGGACCCCGTGTTCGAAGGACCCCTTTGAAATGGTGCCCTGTTTTAATATGCTAAGCGGGCGAATTTTGTTACCTCTTCACTATGAAAGATTCTACACCGCTTATGTCAATAAAACAACGAATAGTCCTTTGAACGCGGACAAACTGCTAAACCGCCTAGTGGGTATGATAAGCTATGCTGGAAACCAAAATGAACTCAACAAGCTATTCCCTACAGAACTTCCTCTTATTATAGAAAAGGTTGAAATGTCCCCCGAGCAGTATAGGCAATATCTGCTGGCCCGGGACGTTGAAAACGCGGAAAAGCACGCCAGCTCAGGAATGCACGAAAAAATAAATACCGCTGCCCTCTGCCTGCCAGGATCGGAGCAAGAGTCAGGCTCCTCCTACTATGTGCGTTCCCGCATGATCAGCATCTTCGCGTCCGAAATGCTAACCATAAAAGAGGATGAAAAATTATCAGAGGCTGTTCAGCAGCTGCCCAAAGAGGCCTTCACAGAAACCTCTAGTCCCAAAATAGTATGCATGCTAAAAAATATTAAAACGTCTCCGGGCCCTGTGCTCATTTACTCCCAGTTTGTGGAACTGGGCCTTCACGTAGTGGCTCGCTTTTTAGAAATAGAGGGCTATCAGTGCCTTCAGCCCCTAAAGGTACTAGAAGAAGGGCACAACGCCATCCTTCTTCATAAGGATGGGAAAGATCTTATGGTGAAAAACTTTGCGGAAGATGAGCCGACCCATACGTTAGTCCTGTCCTCCAAAATAACACGATTTACTCTTATTACAGGAAAAATTTTATCTAAGGAGCGTGACATGATCCAGCAGCTTTGGAATTCGCCGCTGAATATACACGGAGAGGTTATTAAAATTTTACTCGTCTCTAAAACGGGAGCTGAGGGATTGGATCTCAAATACGGGCGGCAGGTTCATATCCTAGAGCCGTACTGGGATAAGGCCCGAGAGGATCAAGTGAAGGCGCGCATTATACGCATTGGTAGCCACGATGCGCTACCGCCTGAGGAGAAAACCGTACAGCCTTTTTTGTACATCGCGGTGGCTAATCAAAAAATGTTTTATAGTATTCCCGAAGGCAGTCAGGAACAAAAAACGATCGATGAGCGTTTTCACGAAAGGGGGCTTGAAAAAAGCCATCTTAATTCTGCTTTCCGCGATTTACTAAAAAGGGCAGCCATTGAATGCGCCTTCAACGGCGAAAGCGGCTGCCTGATGTGTCAGCCCACAAATGCTCTGCTTTTTCATGAAAACTTTGAACGCGACTTACGTTTGCCCAATCCCTGCCAACCGCTTGTAAAAACCGAAGTAAAAGCCTATAGCATATCCTACGAGGGCAAACAGTTTTTTTACCAAAAAAACAAAGGGGTAGGATTAGGCTATACCTTTTATGAATACAATCCCATCATTAAGGCATATATTGAAATTAAACCTTCTAATCCTTTATATATAAAATTAATAAAACATGTCCAGGCCGGAACAACAGTTTAA
Protein
MSCVHNNTSFPVQIEAYLKEVFEKYKELQESKDTSLTARFARALKYYQFLIYTAFSDPKFGIGQGENTRGLLIYHQMGMGKTILSLSLAISLSHIYNPILIAPKSLHSNFQQSLLKLIKLLYPETTDPSKELQKISRRFRFVSLDAYNMGQQIIKAGGSLNGCLLIVDEAHNLFRGIINSANDKTNARQLYNNIMQAKNIRILFLTGTPCSKDPFEMVPCFNMLSGRILLPLHYERFYTAYVNKTTNSPLNADKLLNRLVGMISYAGNQNELNKLFPTELPLIIEKVEMSPEQYRQYLLARDVENAEKHASSGMHEKINTAALCLPGSEQESGSSYYVRSRMISIFASEMLTIKEDEKLSEAVQQLPKEAFTETSSPKIVCMLKNIKTSPGPVLIYSQFVELGLHVVARFLEIEGYQCLQPLKVLEEGHNAILLHKDGKDLMVKNFAEDEPTHTLVLSSKITRFTLITGKILSKERDMIQQLWNSPLNIHGEVIKILLVSKTGAEGLDLKYGRQVHILEPYWDKAREDQVKARIIRIGSHDALPPEEKTVQPFLYIAVANQKMFYSIPEGSQEQKTIDERFHERGLEKSHLNSAFRDLLKRAAIECAFNGESGCLMCQPTNALLFHENFERDLRLPNPCQPLVKTEVKAYSISYEGKQFFYQKNKGVGLGYTFYEYNPIIKAYIEIKPSNPLYIKLIKHVQAGTTV

Summary

Catalytic Activity
ATP + H2O = ADP + H(+) + phosphate
Similarity
Belongs to the DEAD box helicase family. DEAH subfamily.
Keywords
ATP-binding   Complete proteome   Helicase   Hydrolase   Nucleotide-binding   Reference proteome  
Feature
chain  Putative ATP-dependent RNA helicase Q706L
Pfam
PF00176   SNF2_N
PF00271   Helicase_C
Interpro
IPR014001   Helicase_ATP-bd
IPR027417   P-loop_NTPase
IPR038718   SNF2-like_sf
IPR001650   Helicase_C
IPR000330   SNF2_N
SUPFAM
SSF52540   SSF52540
Gene 3D
PDB
6RFL     E-value=2.8265e-14,     Score=194

Ontologies

KEGG

Subcellular Location

From MSLVP
Nucleus

Topology

Length:
706
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
3.41472000000001
Exp number, first 60 AAs:
0.02532
Total prob of N-in:
0.16718
outside
1  -  706
 
 

Population Genetic Test Statistics

Pi
0.0265792
Theta
0.0409595
Tajima's D
-1.1426718
CLR
0.082005
Interpretation
No evidence of Selection

Genomic alignment in the CDS region

 
 

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
AKO62802.1
China_AnhuiXCGQ_2018 Protein
AYW34092.1
China_ASFV-SY18_2018 Protein
AKO62802.1
Poland_Pol16_20186_o7_2016-2017 Protein
AXZ95894.1
Poland_Pol16_20538_o9_2016-2017 Protein
CAN10221.1
Poland_Pol16_20540_o10_2016-2017 Protein
CAN10221.1
Poland_Pol16_29413_o23_2016-2017 Protein
CAN10221.1
Poland_Pol17_03029_C201_2016-2017 Protein
CAN10221.1
Poland_Pol17_04461_C210_2016-2017 Protein
AXZ96177.1
Poland_Pol17_05838_C220_2016-2017 Protein
CAN10221.1
Poland_ASFV_POL_Podlaskie_2015 Protein
CAN10221.1
Uganda_R8_2015 Protein
AXB49350.1
Uganda_R7_2015 Protein
AXB49524.1
Uganda_R25_2015 Protein
AXB49696.1
Uganda_N10_2015 Protein
AXB49867.1
Uganda_R35_2015 Protein
AXB50040.1
Estonia_2014 Protein
SPS73544.1
Italy_26544_OG10_2010 Protein
AJZ77053.1
Italy_47_Ss_2008_2008 Protein
AOO54488.1
Portugal_OURT_88.3_1988 Protein
CAN10470.1
Spain_E75_1975 Protein
CBH29221.1
Russia_Georgia_2007 Protein
CBW46787.1
Kenya_Tk1_2005 Protein
AJL34134.1
Kenya_Bus_2006 Protein
AJL34299.1
Russia_Odintsovo_2014 Protein
CAN10221.1
Portugal_L60_1960 Protein
AIY22312.1
Portugal_NHV_1968 Protein
AIY22470.1
Russia_Kashino_2013 Protein
CAN10221.1
Benin_1997 Protein
Protein
CAN10221.1
CAN10221.1
South_Africa_KNP_Pretorisuskop_1996 Protein
CAN10221.1
South_Africa_MGR_Mkuzi_1979 Protein
CAN10221.1
Malawi_Lil_1983 Protein
CAN10221.1
Kenya_1950 Protein
CAN10221.1
Namibia_Warthog_1980 Protein
CAN10221.1
South_Africa_Warmbaths_1987 Protein
CAN10221.1
Malawi_Tengani_1962 Protein
CAN10221.1
China_HLJ_2018 Protein
QBH90609.1
China_LN_2018 Protein
QBH90794.1
China_wbBS01_2018 Protein
QDL88152.1
Ukraine_Kyiv_2014 Protein
Protein
QED21731.1
QED21732.1
Belgium_Etalle_wb_2018 Protein
QED90564.1
Lithuania_LT14_2014 Protein
QEY87927.1
South_Africa_1985    
South_Africa_2_2008    
Zambia_LIV_1983    
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