ASFVdb The African Swine Fever Virus Database
Strain
South_Africa_1985 (Region: South Africa;  Strain: SPEC_57;  Date: 1985)
Gene
p505_5R
Description
Annotated in NCBI,  505_5R
GenBank Accession
Full name
Protein MGF 505-5R       + More
Protein MGF 505-10R      
Protein MGF 505-2R      
Protein MGF 505-7R      
Protein MGF 505-4R      
Protein MGF 505-6R      
Protein MGF 505-1R      
 

Sequence

CDS
ATGTTCTCCCTCCAGGAGATCTGTCGAAAGAACATCTACTTTCTACCTGTCTGGCTCAGTGTGCATGTGTTTCAGCGACTACGTCTGTACTGGGAAAAACATGGTTCTCTTCAGCGAATCGGAGACGACTATGTACTTATACAACAGGATCTCATCATCCCCATCAATGCAGCTCTACGAATGGCAGGAGAGGAGGGGAGTGTTGTGGTGGTACAACTCTTATTACTATGGGAGGGAAACATTCATTATGCCATCGTACGAGCTTTGGAGGGTGTCCATTATACCCTATTCCGTATGCTCTATGTCCAAATCGAAGACTGTCACGACATCCTTCCCTTATTTCAAGACCCAAAAATCTTTGCAAAATGTCATGTATTACATATATCCTGTATTATTTCATGTCTCGTATTACACGCCGTACAAAACGATATGCTTTGCATTCTTCAAGAATATACAATGCGTCTATGTGGAGGGGATATCCAAGAAGTGTTTGCAACAGCATGCCGTTCGCAAAAATACGATATTGTGTCATGGATGGGAGAAAATATCGCAATATACAACCCGGGAGTCGTTTTTGTTATTGCCTTTGTTCTGTTACATGTATCCTTATTATCTATACGGTATACGCTACTTTTCGATCATCATATATATATTATGTATGCAAATATTGTTTCTTTATTGGCACAACATCTTGTATGGGCTGCCGGCATGGGCCTTCTCCATTTTATGTTGGAAACTTTATACTATGGCGGGGATGTATCGATATCAGTCTTGTCTGTGGCCGTACAATATGTCCACAGAAAGGTTTTACATTATTTTCTCCGTCGAAAAAACTTGTACCAAGAAGACCTTGCAGAACTATTATTGTTGGCGATACGTGCAGATTGTTCTACAAAGACCTTATACTTGTTATTATCTTACTTATACTATTCCATATACAATATCCGTACAAAAATATTACAATGTGTACAAGAATATGCAACGACCATTATTATACAAATTTTATGGAAAAGAAAGATATATCTGTTACGACCCATTTTGGCAGACTTTATACGATATCATACCTATACCTATATGGTACATTTTATGCGTGTGTTTTCCATCCATCCGGAAAAAATGTTCAAAATGGCTGCACGAGAATCGAGGGAGGACTTGTTCATACAATTTTCCAAAAATGTTTGCAAAGAGCCTACAGATACACTTCACTATCTCAAAAGCTTACTGTATACTATGCGACATACAGAAGGCAAACAACTGTTATTTTATACAATCCATATCTTATACAAAGCTTGTCATCTACAGAGTACAGAAATGTTTATCTTGGCACGATTTTATGCACGACATATTGCAGTATTCCAGTTTACATCGATTTGTCACGATCTCTCCAAGCTGTATATTATTATCAAAAACTTGCTTTTACAATGTTTATGGATTGCTATTACAAAAAATTACCCTCAACTTATCAAAACAATACAAACGGATATGTGTTATGTGTAA
Protein
MFSLQEICRKNIYFLPVWLSVHVFQRLRLYWEKHGSLQRIGDDYVLIQQDLIIPINAALRMAGEEGSVVVVQLLLLWEGNIHYAIVRALEGVHYTLFRMLYVQIEDCHDILPLFQDPKIFAKCHVLHISCIISCLVLHAVQNDMLCILQEYTMRLCGGDIQEVFATACRSQKYDIVSWMGENIAIYNPGVVFVIAFVLLHVSLLSIRYTLLFDHHIYIMYANIVSLLAQHLVWAAGMGLLHFMLETLYYGGDVSISVLSVAVQYVHRKVLHYFLRRKNLYQEDLAELLLLAIRADCSTKTLYLLLSYLYYSIYNIRTKILQCVQEYATTIIIQILWKRKIYLLRPILADFIRYHTYTYMVHFMRVFSIHPEKMFKMAARESREDLFIQFSKNVCKEPTDTLHYLKSLLYTMRHTEGKQLLFYTIHILYKACHLQSTEMFILARFYARHIAVFQFTSICHDLSKLYIIIKNLLLQCLWIAITKNYPQLIKTIQTDMCYV

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Similarity
Belongs to the asfivirus MGF 505 family.
Keywords
Complete proteome   Reference proteome   ANK repeat   Repeat  
Feature
chain  Protein MGF 505-5R
EMBL
AY261366    AY261363    KM262845    AIY22378.1    AM712240    CAN10376.1    + More
AM712239    CAN10127.1    FN557520    CBH29129.1    KM262844    KM102979    KP055815    KX354450    AIY22219.1    AJZ77066.1    AKO62710.1    AOO54354.1    U02468    U18466    FR682468    CBW46693.1    LS478113    SPS73450.1    MG939583    MG939587    MG939588    AXZ95806.1    AXZ95994.1    AXZ96089.1    AY261361    AY261360    KM111295    MH025916    MH025917    MH025918    MH025919    MH025920    AJL34209.1    AXB49258.1    AXB49432.1    AXB49604.1    AXB49775.1    AXB49948.1    KM111294    AJL34044.1    AJL34212.1    AXB49261.1    AXB49435.1    AXB49607.1    AXB49778.1    AXB49951.1    AJL34047.1    MH910496    AZP54156.1    CBW46697.1    AXZ95809.1    AXZ95997.1    AXZ96092.1    SPS73454.1    U03761    AIY22382.1    CAN10131.1    CAN10380.1    AIY22223.1    AKO62714.1    AJZ77055.1    AOO54359.1    CBH29133.1    CBH29126.1    MN194591    QED21580.1    CBW46689.1    AXZ95802.1    AXZ95990.1    AXZ96085.1    SPS73446.1    CAN10124.1    AIY22216.1    AJZ77062.1    AKO62707.1    AOO54349.1    AJL34041.1    AJL34206.1    AXB49255.1    AXB49429.1    AXB49601.1    AXB49773.1    AXB49945.1    U03762    CAN10128.1    CBH29130.1    CAN10377.1    AIY22220.1    AIY22379.1    AJZ77060.1    AKO62711.1    AOO54355.1    CBW46695.1    SPS73452.1    AJL34045.1    AXB49259.1    AXB49433.1    AXB49605.1    AXB49776.1    AXB49949.1    AJL34210.1    CBW46694.1    AXZ95807.1    AXZ95995.1    AXZ96090.1    SPS73451.1    CAN10126.1    CBH29128.1    CAN10375.1    AIY22218.1    AIY22377.1    AJZ77065.1    AKO62709.1    AOO54353.1    AXB49257.1    AXB49431.1    AXB49603.1    AXB49947.1    AJL34208.1    CAN10129.1    AIY22221.1    AJZ77061.1    CBH29131.1    AJL34043.1    CBW46692.1    AXZ95993.1    AXZ96088.1    SPS73449.1    AXZ95805.1    QED21582.1    AOO54356.1    AKO62712.1    AIY22380.1    CAN10378.1    QED21575.1    AJZ77058.1    AOO54340.1    CBW46685.1    AXZ95798.1    AXZ95986.1    AXZ96081.1    SPS73442.1    AXB49251.1    AXB49425.1    AXB49597.1    AXB49770.1    AXB49941.1    CAN10120.1    CBH29122.1    AIY22212.1    AKO62703.1    AJL34201.1    AJL34037.1   
Pfam
PF03158   DUF249
Interpro
IPR004858   MGF_505
IPR036770   Ankyrin_rpt-contain_sf
SUPFAM
SSF48403   SSF48403
Gene 3D

Ontologies

Subcellular Location

From MSLVP
Capsid

Topology

Length:
498
Number of predicted TMHs:
2
Exp number of AAs in TMHs:
79.82195
Exp number, first 60 AAs:
0.61062
Total prob of N-in:
0.62704
outside
1  -  188
TMhelix
189  -  211
inside
212  -  217
TMhelix
218  -  240
outside
241  -  498
 
 

Population Genetic Test Statistics

Pi
0.1201523
Theta
0.1174554
Tajima's D
0.0552144
CLR
0
Interpretation
Possibly Balancing Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
AKO62710.1
China_AnhuiXCGQ_2018 Protein
AYW33999.1
China_ASFV-SY18_2018 Protein
AKO62710.1
Poland_Pol16_20186_o7_2016-2017 Protein
AXZ95806.1
Poland_Pol16_20538_o9_2016-2017    
Poland_Pol16_20540_o10_2016-2017    
Poland_Pol16_29413_o23_2016-2017    
Poland_Pol17_03029_C201_2016-2017 Protein
AXZ95994.1
Poland_Pol17_04461_C210_2016-2017 Protein
AXZ96089.1
Poland_Pol17_05838_C220_2016-2017    
Poland_ASFV_POL_Podlaskie_2015    
Uganda_R8_2015 Protein
AXB49258.1
Uganda_R7_2015 Protein
AXB49432.1
Uganda_R25_2015 Protein
AXB49604.1
Uganda_N10_2015 Protein
AXB49775.1
Uganda_R35_2015 Protein
AXB49948.1
Estonia_2014 Protein
SPS73450.1
Italy_26544_OG10_2010 Protein
AJZ77066.1
Italy_47_Ss_2008_2008 Protein
AOO54354.1
Portugal_OURT_88.3_1988 Protein
CAN10376.1
Spain_E75_1975 Protein
CBH29129.1
Russia_Georgia_2007 Protein
CBW46693.1
Kenya_Tk1_2005 Protein
AJL34044.1
Kenya_Bus_2006 Protein
AJL34209.1
Russia_Odintsovo_2014    
Portugal_L60_1960 Protein
AIY22219.1
Portugal_NHV_1968 Protein
AIY22378.1
Russia_Kashino_2013    
Benin_1997 Protein
CAN10127.1
South_Africa_KNP_Pretorisuskop_1996 Protein
QGM12816.1
South_Africa_MGR_Mkuzi_1979    
Malawi_Lil_1983    
Kenya_1950    
Namibia_Warthog_1980    
South_Africa_Warmbaths_1987    
Malawi_Tengani_1962    
China_HLJ_2018 Protein
QBH90515.1
China_LN_2018 Protein
QBH90700.1
China_wbBS01_2018 Protein
QDL88058.1
Ukraine_Kyiv_2014 Protein
QED21584.1
Belgium_Etalle_wb_2018 Protein
QED90470.1
Lithuania_LT14_2014 Protein
QEY87833.1
South_Africa_1985 Protein
Protein
QGM12816.1
QGM12892.1
South_Africa_2_2008 Protein
Protein
Protein
QGM12816.1
QGM12816.1
QGM12817.1
Zambia_LIV_1983    
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