Strain

South_Africa_2_2008 (Region: South Africa; Strain: RSA_2_2008; Date: 2008)

Gene

pCP80R

Description

Annotated in NCBI, CP80R

Location

MN336500.1(+):125885-126127

GenBank Accession

QGM12851.1

Full name

Putative DNA-directed RNA polymerase subunit 10 homolog + More
DNA-directed RNA polymerase subunit N

CDS

ATGTTGTTACCTGTGGTGTGTTTTACCTGTGGGTTTCCTATTGGAACCTACGCGGCAATTTTTGTCAAGGCTCGTACCGAGTATATTACAACCAAAATGGGCGGAACATTACCGCAAAATATTCCATTACATGCCTCTCTCCAGATTGTGTTACAAGACCTCATTACAGCTCTGGGAATCCCAATGCGAGTGTGTTGTCGCACTCATTTATTTACTACGTTGGATTATCGTATATATTATTAA

Protein

MLLPVVCFTCGFPIGTYAAIFVKARTEYITTKMGGTLPQNIPLHASLQIVLQDLITALGIPMRVCCRTHLFTTLDYRIYY

Function

Component of the DNA-dependent RNA polymerase that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic Activity

a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)

Subunit

Component of the RNA polymerase that consists of at least 6 subunits.

Similarity

Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.

Keywords

Complete proteome DNA-directed RNA polymerase Host cytoplasm Metal-binding Transcription Zinc Reference proteome

Feature

chain Putative DNA-directed RNA polymerase subunit 10 homolog

Uniprot

E0WM45 A0A0C5BCR6 P0C981 P0C979 P0C980 P0C982 + More
A9JL60 D4I5T2 A9JLZ1 A0A0A1E360 P42488 A0A385KML8 A0A0N7CSV1 A0A5E4J3F7 A0A256ZVM6 A0A5A7S5Q3 A0A076FI51 A0A2R6MBR8 A0A1F9YMT1

EC Number

2.7.7.6

Pubmed

21470447 25645905 18198370 25406173 11831707 26618713 + More
25035289 28804480 27774985

EMBL

FR682468 CBW46761.1 KM111294 KM111295 MH025916 MH025917 + More
MH025918 MH025919 MH025920 LS478113 AJL34108.1 AJL34273.1 AXB49323.1 AXB49497.1 AXB49669.1 AXB49840.1 AXB50013.1 SPS73518.1 AY261366 AY261363 AY261361 AY261360 AM712239 CAN10194.1 FN557520 CBH29195.1 AM712240 CAN10444.1 KM262844 KM262845 KM102979 KX354450 AIY22286.1 AIY22444.1 AJZ77182.1 AOO54445.1 U18466 MG939583 MG939587 MG939588 AXZ95869.1 AXZ96057.1 AXZ96152.1 KP055815 AKO62776.1 CABMDW010000063 VVB70841.1 NJEP01000063 OYT56666.1 VBQG01000003 KAA0018008.1 KJ645900 AII17126.1 PXSM01000016 PSQ50631.1 MGVV01000050 OGS40899.1

Proteomes

UP000141072 UP000101566 UP000105860 UP000000858 UP000000859 UP000000860 + More
UP000000861 UP000130745 UP000101090 UP000108903 UP000110401 UP000117635 UP000142390 UP000266411 UP000000624 UP000241813 UP000216972 UP000324442 UP000028667

Pfam

PF01194 RNA_pol_N

Interpro

IPR000268   RNAP_N/Rpb10
IPR020789   RNA_pol_suN_Zn-BS
IPR023580   RNA_pol_su_RPB10

SUPFAM

SSF46924 SSF46924

ProteinModelPortal

E0WM45 A0A0C5BCR6 P0C981 P0C979 P0C980 P0C982 + More
A9JL60 D4I5T2 A9JLZ1 A0A0A1E360 P42488 A0A385KML8 A0A0N7CSV1 A0A5E4J3F7 A0A256ZVM6 A0A5A7S5Q3 A0A076FI51 A0A2R6MBR8 A0A1F9YMT1

PANTHER

PTHR23431

PDB

1EF4 E-value=0.152983, Score=75

Ontologies

KEGG

vg:22220324 vg:20041512

GO

GO:0003899  F:DNA-directed 5'-3' RNA polymerase activity
GO:0006351  P:transcription, DNA-templated
GO:0003677  F:DNA binding
GO:0008270  F:zinc ion binding
GO:0030430  C:host cell cytoplasm

Subcellular Location

From MSLVP

Single-Pass Membrane

From Uniprot

Host cytoplasm

Topology

Length:

80

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

19.54908

Exp number, first 60 AAs:

19.1279

Total prob of N-in:

0.23138

POSSIBLE N-term signal

sequence

outside

1 - 4

TMhelix

5 - 22

inside

23 - 80

Population Genetic Test Statistics

Pi

0.0279411

Theta

0.0352716

Tajima's D

-0.7472558

CLR

0

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein	AKO62776.1
China_AnhuiXCGQ_2018	Protein	AYW34066.1
China_ASFV-SY18_2018	Protein	AKO62776.1
Poland_Pol16_20186_o7_2016-2017	Protein	AXZ95869.1
Poland_Pol16_20538_o9_2016-2017	Protein	CAN10194.1
Poland_Pol16_20540_o10_2016-2017	Protein	CAN10194.1
Poland_Pol16_29413_o23_2016-2017	Protein	CAN10194.1
Poland_Pol17_03029_C201_2016-2017	Protein	AXZ96057.1
Poland_Pol17_04461_C210_2016-2017	Protein	AXZ96152.1
Poland_Pol17_05838_C220_2016-2017	Protein	CAN10194.1
Poland_ASFV_POL_Podlaskie_2015	Protein	CAN10194.1
Uganda_R8_2015	Protein	AXB49323.1
Uganda_R7_2015	Protein	AXB49497.1
Uganda_R25_2015	Protein	AXB49669.1
Uganda_N10_2015	Protein	AXB49840.1
Uganda_R35_2015	Protein	AXB50013.1
Estonia_2014	Protein	SPS73518.1
Italy_26544_OG10_2010	Protein	AJZ77182.1
Italy_47_Ss_2008_2008	Protein	AOO54445.1
Portugal_OURT_88.3_1988	Protein	CAN10444.1
Spain_E75_1975	Protein	CBH29195.1
Russia_Georgia_2007	Protein	CBW46761.1
Kenya_Tk1_2005	Protein	AJL34108.1
Kenya_Bus_2006	Protein	AJL34273.1
Russia_Odintsovo_2014	Protein	CAN10194.1
Portugal_L60_1960	Protein	AIY22286.1
Portugal_NHV_1968	Protein	AIY22444.1
Russia_Kashino_2013	Protein	CAN10194.1
Benin_1997	Protein Protein	CAN10194.1 CAN10194.1
South_Africa_KNP_Pretorisuskop_1996	Protein	CAN10194.1
South_Africa_MGR_Mkuzi_1979	Protein	CAN10194.1
Malawi_Lil_1983	Protein	CAN10194.1
Kenya_1950	Protein	CAN10194.1
Namibia_Warthog_1980	Protein	CAN10194.1
South_Africa_Warmbaths_1987	Protein	CAN10194.1
Malawi_Tengani_1962	Protein	CAN10194.1
China_HLJ_2018	Protein	QBH90583.1
China_LN_2018	Protein	QBH90768.1
China_wbBS01_2018	Protein	QDL88126.1
Ukraine_Kyiv_2014	Protein	CAN10194.1
Belgium_Etalle_wb_2018	Protein	QED90538.1
Lithuania_LT14_2014	Protein	QEY87901.1
South_Africa_1985	Protein	QGM12925.1
South_Africa_2_2008	Protein	QGM12851.1
Zambia_LIV_1983	Protein	QGM12738.1

Sequence