Strain

Ukraine_Kyiv_2014 (Region: Ukraine; Strain: ASFV/Kyiv/2016/131; Date: 2014)

Gene

hypothetical protein ASFV_Kyiv_2016_131_00019

Description

Annotated in NCBI, ASFV_Kyiv_2016_131_00019

Location

MN194591.1(-):13874-14182

GenBank Accession

QED21555.1

Full name

Protein MGF 110-9L       + More
Protein LIS 290
Protein LIS 117
Protein MGF 110-13L
Protein LIS 119-1
Protein MGF 360-3L
Protein MGF 110-11L
Protein MGF 360-1L

CDS

ATGAAGGTGATTGTGTTCCTTTTGGTACTGGCGGTCATGCAGCCGGTCATTCAAAGCCAATCTTTTCCAGGAACAGGAGAGTTACCAATGACCCGGAGACCTCCAAAGAGAGAGCTTGAGTATTGGTGCACCTATGCAAAATCGTGTGACTTCTGCTGGAATTGTCGACACGGGGTTTGTAAAAATAAGGTTTTTGAAAAACACCCTCTCATCAAAAAAATGATTACATACAAATATGTAGGGTTTCTCGCTATAATGAAAGATGTAGCTACTTTACAGACTCTAGGATACGCCGCTTTCACATCATGA

Protein

MKVIVFLLVLAVMQPVIQSQSFPGTGELPMTRRPPKRELEYWCTYAKSCDFCWNCRHGVCKNKVFEKHPLIKKMITYKYVGFLAIMKDVATLQTLGYAAFTS

Function

Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.

Similarity

Belongs to the asfivirus MGF 110 family.
Belongs to the asfaviruses V110 family.

Keywords

Complete proteome Glycoprotein Host membrane Membrane Transmembrane Transmembrane helix Early protein Repeat Signal

Feature

chain Protein MGF 110-9L

Uniprot

A0A5B8XA38 E0WMD4 A0A385KMQ4 P0C9J0 A0A0C5AYT5 A0A0C5AZS1 + More
A0A2Z5DGN8 P0C9J1 P0C9I9 P26710 A0A0A1DY81 A9JLJ4 A0A0C5BC29 A0A2Z5DG86 A0A0C5B2D9 A0A2Z5DFP2 P26702 A0A485PYX9 A0A5J6RCT9 A0A0A1E020 A9JKS3 P0C9K1 P0C9K0 A0A1C6ZY46 P26703 A0A2Z5DET6 A0A485PU32 E0WMD6 A0A385KMG0 A9JLJ5 A0A0A1E3E0 A0A0C5AWJ1 P0C9J5 A0A5J6RD08 A0A385KMA0 A0A3S9JK74 A0A5K1HWK4 A0A5B8XEI3 A0A3S9JJL3 E0WME0 A0A385KLX5 A0A3G1EUS1 P0C9J3 A0A3G1EUS4 A0A0A1DXZ3 A0A485PSL7 A0A0C5B216 P0C9J4 A0A485PV23 E0WMD7 A0A385KLX6 A0A3Q9CZA7 A0A3Q9CZL8 P0C9J6 A0A2Z5DF04 A0A0C5AZ57 A0A0C5AW82 A0A2Z5DFZ9 A0A2Z5DG96 D4I5J4 A0A3G1EUT0 A0A0A1DXF6

Pubmed

21470447 25645905 2219721 25406173 18198370 25808027 + More
30547827 30637968

EMBL

MN194591 QED21555.1 FR682468 CBW46662.1 MG939583 MG939586 + More
MG939587 MG939588 AXZ95782.1 AXZ95962.1 AXZ95979.1 AXZ96074.1 AY261360 KM111294 AJL34022.1 KM111295 AJL34185.1 MH025916 MH025917 MH025918 MH025919 MH025920 AXB49235.1 AXB49409.1 AXB49582.1 AXB49754.1 AXB49925.1 AY261363 AY261366 M58155 KM262845 AIY22365.1 AM712240 CAN10363.1 AJL34023.1 AXB49236.1 AXB49410.1 AXB49755.1 AXB49926.1 AJL34186.1 AXB49583.1 LR536725 VFV47934.1 MK628478 QEY87807.1 KM262844 AIY22199.1 AM712239 CAN10107.1 AY261361 KM102979 AJZ77135.1 AXB49239.1 AXB49413.1 AXB49585.1 AXB49758.1 AXB49929.1 VFV47930.1 CBW46664.1 MG939584 AXZ95784.1 AXZ95937.1 AXZ95964.1 AXZ95981.1 AXZ96076.1 CAN10364.1 AIY22366.1 AJL34189.1 QEY87803.1 AXZ95940.1 MH910496 AZP54211.1 LR722600 VVW94007.1 QED21559.1 MH910495 AZP54032.1 CBW46668.1 AXZ95787.1 KX354450 AOO54322.1 AOO54321.1 AIY22367.1 VFV47929.1 AJL34026.1 VFV47931.1 CBW46665.1 AXZ95785.1 AXZ95938.1 AZP54088.1 MK128995 AYW33966.1 AZP54271.1 QED21557.1 AXB49237.1 AXB49411.1 AJL34187.1 AJL34024.1 AXB49927.1 AXB49756.1 FN557520 CBH29107.1 AOO54319.1 AIY22197.1

Proteomes

UP000321214 UP000141072 UP000000861 UP000105860 UP000101566 UP000000859 + More
UP000000858 UP000110401 UP000108903 UP000142390 UP000130745 UP000000860 UP000117635 UP000266411 UP000307568 UP000290386 UP000101090

PRIDE

P0C9I9 P26710

Pfam

PF01639 v110

Interpro

IPR004848 V110_vir

ProteinModelPortal

A0A5B8XA38 E0WMD4 A0A385KMQ4 P0C9J0 A0A0C5AYT5 A0A0C5AZS1 + More
A0A2Z5DGN8 P0C9J1 P0C9I9 P26710 A0A0A1DY81 A9JLJ4 A0A0C5BC29 A0A2Z5DG86 A0A0C5B2D9 A0A2Z5DFP2 P26702 A0A485PYX9 A0A5J6RCT9 A0A0A1E020 A9JKS3 P0C9K1 P0C9K0 A0A1C6ZY46 P26703 A0A2Z5DET6 A0A485PU32 E0WMD6 A0A385KMG0 A9JLJ5 A0A0A1E3E0 A0A0C5AWJ1 P0C9J5 A0A5J6RD08 A0A385KMA0 A0A3S9JK74 A0A5K1HWK4 A0A5B8XEI3 A0A3S9JJL3 E0WME0 A0A385KLX5 A0A3G1EUS1 P0C9J3 A0A3G1EUS4 A0A0A1DXZ3 A0A485PSL7 A0A0C5B216 P0C9J4 A0A485PV23 E0WMD7 A0A385KLX6 A0A3Q9CZA7 A0A3Q9CZL8 P0C9J6 A0A2Z5DF04 A0A0C5AZ57 A0A0C5AW82 A0A2Z5DFZ9 A0A2Z5DG96 D4I5J4 A0A3G1EUT0 A0A0A1DXF6

PDB

6NNF E-value=7.6554, Score=60

Ontologies

GO

GO:0016021 C:integral component of membrane
GO:0033644 C:host cell membrane

Subcellular Location

From MSLVP

Host nucleus > host nucleolus. Host cytoplasm. Secreted.

From Uniprot

Host membrane

Topology

Length:

102

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

6.07159

Exp number, first 60 AAs:

1.16929

Total prob of N-in:

0.23540

outside

1 - 102

Population Genetic Test Statistics

Pi

0.1909255

Theta

0.2811178

Tajima's D

-1.4550914

CLR

0.327202

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971
China_AnhuiXCGQ_2018
China_ASFV-SY18_2018
Poland_Pol16_20186_o7_2016-2017
Poland_Pol16_20538_o9_2016-2017
Poland_Pol16_20540_o10_2016-2017
Poland_Pol16_29413_o23_2016-2017
Poland_Pol17_03029_C201_2016-2017
Poland_Pol17_04461_C210_2016-2017
Poland_Pol17_05838_C220_2016-2017
Poland_ASFV_POL_Podlaskie_2015
Uganda_R8_2015
Uganda_R7_2015
Uganda_R25_2015
Uganda_N10_2015
Uganda_R35_2015
Estonia_2014
Italy_26544_OG10_2010
Italy_47_Ss_2008_2008
Portugal_OURT_88.3_1988
Spain_E75_1975
Russia_Georgia_2007
Kenya_Tk1_2005
Kenya_Bus_2006
Russia_Odintsovo_2014
Portugal_L60_1960
Portugal_NHV_1968
Russia_Kashino_2013
Benin_1997
South_Africa_KNP_Pretorisuskop_1996
South_Africa_MGR_Mkuzi_1979
Malawi_Lil_1983
Kenya_1950
Namibia_Warthog_1980
South_Africa_Warmbaths_1987
Malawi_Tengani_1962
China_HLJ_2018
China_LN_2018
China_wbBS01_2018
Ukraine_Kyiv_2014	Protein	QED21555.1
Belgium_Etalle_wb_2018
Lithuania_LT14_2014
South_Africa_1985
South_Africa_2_2008
Zambia_LIV_1983

Sequence