Strain

Poland_Pol17_03029_C201_2016-2017 (Region: Poland;  Strain: Pol17_03029_C201;  Date: 2016-2017)

Gene

EP153R

Description

Annotated in NCBI,  EP153R

Location

MG939587.1(+):72845-73321

GenBank Accession

AXZ96020.1

Full name

Lectin-like protein EP153R      

CDS

ATGTTTTCTAACAAAAAGTACATCGGTCTTATCAATAAGAAGGAGGGTTTGAAAAAAAAAATAGATGATTATAGTATATTAATAATTGGAATATTAATTGGAACTAACATCTTAAGCCTTATTATAAATATAATAGGAGAGATTAATAAACCAATATGTTACCAAAATGATGATAAGATATTTTATTGCCCTAAAGATTGGGTTGGATATAATAATGTTTGTTATTATTTTGGCAATGAAGAAAAAAATTATAATAATGCAAGTAATTATTGTAAGCAATTAAATAGTACGCTTACTAATAATAATACTATTTTAGTAAATCTTACTAAAACATTAAATCTTACTAAAACATATAATCACGAATCTAATTATTGGGTTAATTATTCTTTAATTAAAAATGAGTCAGTACTATTACGTGATAGTGGATATTACAAAAAACAAAAACATGTAAGTTTATTATATATTTGTAGTAAATAA

Protein

MFSNKKYIGLINKKEGLKKKIDDYSILIIGILIGTNILSLIINIIGEINKPICYQNDDKIFYCPKDWVGYNNVCYYFGNEEKNYNNASNYCKQLNSTLTNNNTILVNLTKTLNLTKTYNHESNYWVNYSLIKNESVLLRDSGYYKKQKHVSLLYICSK

Function

Participates to viral hemadsorption, which may help viral spread. Reduces the transactivating activity of host TP53, thus inhibiting apoptosis (By similarity). Non-essential for virus growth in swine macrophage cell cultures (By similarity).
Participates to viral hemadsorption, which may help viral spread. Reduces the transactivating activity of host TP53, thus inhibiting apoptosis (By similarity). Non-essential for virus growth in swine macrophage cell cultures (PubMed:10573162).

Similarity

Belongs to the asfivirus lectin-like protein family.

Keywords

Complete proteome   Glycoprotein   Host membrane   Host-virus interaction   Lectin   Membrane   Modulation of host cell apoptosis by virus   Signal-anchor   Transmembrane   Transmembrane helix   Late protein  

Feature

chain  Lectin-like protein EP153R

Uniprot

E0WMJ5   A0A0A7W5A0   P0CA65   O89338   O89330   A0A0A7WCA2   + More
A0A0A7W520   O89329   A0A0A7W6T2   O89334   P0CA64   O89331   A0A0A7W576  

Pubmed

21470447    25524164    10573162   

EMBL

FR682468    CBW46723.1    KM609342    KM609360    KM609362    KM609363    + More
KU752730    KU752731    KU752732    KU752733    KU752734    KU752735    KU752736    KU752737    KU752738    KU752739    KU752740    KU752741    KU752742    KU752743    KU752744    KU752745    KU752746    KU752747    KU752748    KU752749    KU752750    KU752751    KU752752    KU752753    KU752754    KU752755    KU752756    KU752757    KU752758    KU752759    KU752760    KU752761    KU752762    KU752763    KU752764    KU752765    KU752766    KU752767    KU752768    KU752769    KU752770    KU752771    KU752772    KU752773    KU752774    KU752775    KU752776    KU752777    KU752778    KU752779    KU752780    KU752781    KU752782    KU752783    KU752784    KU752785    KU752786    KU752787    KU752788    KU752789    KU752790    KU752791    KU752792    KU752793    KU752794    KU752795    KU752796    MG939583    MG939587    MG939588    LS478113    AJB28370.1    AJB28402.1    AJB28406.1    AJB28408.1    ANC98852.1    ANC98853.1    ANC98854.1    ANC98855.1    ANC98856.1    ANC98857.1    ANC98858.1    ANC98859.1    ANC98860.1    ANC98861.1    ANC98862.1    ANC98863.1    ANC98864.1    ANC98865.1    ANC98866.1    ANC98867.1    ANC98868.1    ANC98869.1    ANC98870.1    ANC98871.1    ANC98872.1    ANC98873.1    ANC98874.1    ANC98875.1    ANC98876.1    ANC98877.1    ANC98878.1    ANC98879.1    ANC98880.1    ANC98881.1    ANC98882.1    ANC98883.1    ANC98884.1    ANC98885.1    ANC98886.1    ANC98887.1    ANC98888.1    ANC98889.1    ANC98890.1    ANC98891.1    ANC98892.1    ANC98893.1    ANC98894.1    ANC98895.1    ANC98896.1    ANC98897.1    ANC98898.1    ANC98899.1    ANC98900.1    ANC98901.1    ANC98902.1    ANC98903.1    ANC98904.1    ANC98905.1    ANC98906.1    ANC98907.1    ANC98908.1    ANC98909.1    ANC98910.1    ANC98911.1    ANC98912.1    ANC98913.1    ANC98914.1    ANC98915.1    ANC98916.1    ANC98917.1    ANC98918.1    AXZ95832.1    AXZ96020.1    AXZ96115.1    SPS73480.1    AY261366    AF017039    KM609339    KM609341    KM609356    KM609357    AAC28424.1    AJB28365.1    AJB28368.1    AJB28395.1    AJB28397.1    AF017028    AAC28413.1    KM609349    AJB28383.1    KM609359    AJB28400.1    AF017027    AAC28412.1    KM609340    KM609343    KM609344    KM609345    AJB28367.1    AJB28372.1    AJB28374.1    AJB28376.1    AF017035    KM609354    AAC28420.1    AJB28391.1    AY261361    AF017029    AAC28414.1    KM609346    KM609347    AJB28377.1    AJB28379.1   

Proteomes

UP000141072    UP000000858    UP000000860   

PRIDE

P0CA65   

Pfam

PF05473   UL45

Interpro

IPR016186   C-type_lectin-like/link_sf
IPR008646   Herpes_UL45-like
IPR016187   CTDL_fold

SUPFAM

SSF56436   SSF56436

Gene 3D

3.10.100.10    

ProteinModelPortal

E0WMJ5   A0A0A7W5A0   P0CA65   O89338   O89330   A0A0A7WCA2   + More
A0A0A7W520   O89329   A0A0A7W6T2   O89334   P0CA64   O89331   A0A0A7W576  

PDB

3FF7     E-value=0.00582356,     Score=88