Strain

Portugal_L60_1960 (Region: Portugal; Strain: L60; Date: 1960)

Gene

transcription factor SII-like protein

Description

Annotated in NCBI, similar to TFIIS and vaccinia virus E4L

Location

KM262844.1(-):165929-166660

GenBank Accession

AIY22329.1

Full name

Transcription factor S-II-related protein

CDS

ATGAAAATGCATATAGCCCGCGATTCTATCGTATTTTTGCTAAATAAGCATTTGCAAAATACTATCCTTACAAATAAGATTGAACAAGAATGTTTTTTACAGGCTGACACGCCTAAAAAATATTTACAATATATTAAGCCATTTTTAATAAATTGTATGACTAAGAATATTACCACCGATCTAGTTATGAAAGATTCCAAAAGATTAGAACCCTATATTATTTTAGAAATGCGTGATATCATCCAAATGATGTTTTTTAGAACGCTTCAAAAACATATGTTTTTTAAGGAACATACTGATTTATGCACCGAATACGCGCAAAAAATCGAGGCCTCGTGTTATCATTATACGTACCAGCAGCAAGAAAAAACCTTTTTAGAAGAATATTCAACCCGTTGTGGGACGATCAATCATATTATTAATTGCGAAAAAAAAAGTCACCAGCAGCAGGATAACGATGCCCTTAATAAGCTAATTTCTGGCGAGCTAAAACCGGAGGCAATTGGTAGCATGACGTTCGCCGAGCTTTGTCCCTCTGCCGCCTTAAAGGAGAAGACAGAAATTACTCTACGTTCGCAGCAAAAAGTCGCCGAAAAGACGTCACAACTTTATAAGTGTCCCAACTGCAAGCAGCGTATGTGCACCTACAGAGAAGTACAAACACGCGCCCTCGATGAGCCTTCCACGATATTTTGTACCTGTAAAAAATGCGGGCATGAGTTTATTGGCTAA

Protein

MKMHIARDSIVFLLNKHLQNTILTNKIEQECFLQADTPKKYLQYIKPFLINCMTKNITTDLVMKDSKRLEPYIILEMRDIIQMMFFRTLQKHMFFKEHTDLCTEYAQKIEASCYHYTYQQQEKTFLEEYSTRCGTINHIINCEKKSHQQQDNDALNKLISGELKPEAIGSMTFAELCPSAALKEKTEITLRSQQKVAEKTSQLYKCPNCKQRMCTYREVQTRALDEPSTIFCTCKKCGHEFIG

Similarity

Belongs to the TFS-II family.

Keywords

Complete proteome Late protein Metal-binding Transcription Transcription regulation Zinc Zinc-finger Reference proteome

Feature

chain Transcription factor S-II-related protein

Uniprot

P0C8F8 D4I5G2 A9JM71 A0A0A1DYB2 P0C8F7 P27948 + More
A9JLD4 E0WM88 A0A2X0S7F9 A0A0C5AZM3 P0C8F5 A0A2Z5DGE8 A0A2Z5DEZ0 Q65252 P0C8F6

Pubmed

18198370 25406173 26618713 1309282 11831707 8970983 + More
21470447 25645905 8409937

EMBL

AY261366 FN557520 CBH29238.1 AM712240 CAN10487.1 KM262844 + More
KM262845 KM102979 KP055815 KX354450 AIY22329.1 AIY22487.1 AJZ77120.1 AKO62819.1 AOO54509.1 AY261363 M77121 U18466 AM712239 CAN10237.1 FR682468 CBW46804.1 MG939583 MG939588 LS478113 AXZ95910.1 AXZ96193.1 SPS73561.1 KM111294 KM111295 AJL34150.1 AJL34314.1 AY261360 MH025919 AXB49883.1 MH025916 MH025917 MH025918 MH025920 AXB49366.1 AXB49540.1 AXB49712.1 AXB50056.1 X71982 CAA50848.1 AY261361

Proteomes

UP000000858 UP000101090 UP000108903 UP000110401 UP000117635 UP000142390 + More
UP000241813 UP000266411 UP000000859 UP000000624 UP000130745 UP000141072 UP000101566 UP000105860 UP000000861 UP000000860

PRIDE

P0C8F5

Pfam

PF01096 TFIIS_C
PF07500 TFIIS_M

Interpro

IPR001222   Znf_TFIIS
IPR035100   TF_IIS-typ
IPR003618   TFIIS_cen_dom

ProteinModelPortal

P0C8F8 D4I5G2 A9JM71 A0A0A1DYB2 P0C8F7 P27948 + More
A9JLD4 E0WM88 A0A2X0S7F9 A0A0C5AZM3 P0C8F5 A0A2Z5DGE8 A0A2Z5DEZ0 Q65252 P0C8F6

PDB

1PQV E-value=7.29534e-08, Score=133

Ontologies

KEGG

vg:22220367

GO

GO:0003676  F:nucleic acid binding
GO:0006351  P:transcription, DNA-templated
GO:0008270  F:zinc ion binding
GO:0004386  F:helicase activity

Subcellular Location

From MSLVP

Host nucleus > host nucleolus. Host cytoplasm. Secreted.

Topology

Length:

243

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01493

Exp number, first 60 AAs:

0.00305

Total prob of N-in:

0.12704

outside

1 - 243

Population Genetic Test Statistics

Pi

0.0317554

Theta

0.0386849

Tajima's D

-0.51488

CLR

0

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein	AKO62819.1
China_AnhuiXCGQ_2018	Protein	AYW34109.1
China_ASFV-SY18_2018	Protein	AKO62819.1
Poland_Pol16_20186_o7_2016-2017	Protein	AXZ95910.1
Poland_Pol16_20538_o9_2016-2017	Protein	CAN10237.1
Poland_Pol16_20540_o10_2016-2017	Protein	CAN10237.1
Poland_Pol16_29413_o23_2016-2017	Protein	CAN10237.1
Poland_Pol17_03029_C201_2016-2017	Protein	CAN10237.1
Poland_Pol17_04461_C210_2016-2017	Protein	AXZ96193.1
Poland_Pol17_05838_C220_2016-2017	Protein	CAN10237.1
Poland_ASFV_POL_Podlaskie_2015	Protein	CAN10237.1
Uganda_R8_2015	Protein	AXB49366.1
Uganda_R7_2015	Protein	AXB49540.1
Uganda_R25_2015	Protein	AXB49712.1
Uganda_N10_2015	Protein	AXB49883.1
Uganda_R35_2015	Protein	AXB50056.1
Estonia_2014	Protein	SPS73561.1
Italy_26544_OG10_2010	Protein	AJZ77120.1
Italy_47_Ss_2008_2008	Protein	AOO54509.1
Portugal_OURT_88.3_1988	Protein	CAN10487.1
Spain_E75_1975	Protein	CBH29238.1
Russia_Georgia_2007	Protein	CBW46804.1
Kenya_Tk1_2005	Protein	AJL34150.1
Kenya_Bus_2006	Protein	AJL34314.1
Russia_Odintsovo_2014	Protein	CAN10237.1
Portugal_L60_1960	Protein	AIY22329.1
Portugal_NHV_1968	Protein	AIY22487.1
Russia_Kashino_2013	Protein	CAN10237.1
Benin_1997	Protein Protein	CAN10237.1 CAN10237.1
South_Africa_KNP_Pretorisuskop_1996	Protein	CAN10237.1
South_Africa_MGR_Mkuzi_1979	Protein	CAN10237.1
Malawi_Lil_1983	Protein	CAN10237.1
Kenya_1950	Protein	CAN10237.1
Namibia_Warthog_1980	Protein	CAN10237.1
South_Africa_Warmbaths_1987	Protein	CAN10237.1
Malawi_Tengani_1962	Protein	CAN10237.1
China_HLJ_2018	Protein	QBH90626.1
China_LN_2018	Protein	QBH90811.1
China_wbBS01_2018	Protein	QDL88169.1
Ukraine_Kyiv_2014	Protein	QED21754.1
Belgium_Etalle_wb_2018	Protein	QED90581.1
Lithuania_LT14_2014	Protein	QEY87944.1
South_Africa_1985
South_Africa_2_2008
Zambia_LIV_1983

Sequence