ASFVdb The African Swine Fever Virus Database
Strain
Portugal_L60_1960 (Region: Portugal;  Strain: L60;  Date: 1960)
Gene
pMGF 505-1R
Description
Annotated in NCBI,  member of multigene family 505
GenBank Accession
Full name
Protein MGF 505-1R       + More
Protein MGF 505-3R      
Protein MGF 505-4R      
Protein MGF 505-5R      
Protein MGF 505-2R      
Protein MGF 505-10R      
Protein MGF 505-7R      
Protein MGF 505-6R      
 

Sequence

CDS
ATGTTCTCTCTCCAGAACTTATGTCGAAAAACATTACCTGACTGTAAACTTCCTGAATTTTTTGACGATTATATATTACAACTGCTGGGATTATACTGGGAAAACCATGGAACTATTCAACGGGCAGGAAACAACTGTGTGCTTATACAACAACATACCCTCATTCCCGTAAATGAAGCCCTAAGAATAGCAGCATCTGAAGAAAATTATGAGATCGTGGGCCTTTTATTAGCGTGGGAGGGGAACCTTTACTATGCTATTATAGGGGCTCTAGAGGGTAACCGCTACAACTTAATTCGTAAATATGATGATCAAATCAAGGACCATCATGACATTCTGCCATTCATTGATGATCCAATCATATTTCACAAATGCCATATCATGCGGCGATGCTTTTTTGATTGTATTTTATATCAAGCTGTAAAATATAGTAAGTTTCGTGTTCTTCTTTATTTTAAATATACATTAGAGGATGATTTGCCCCTCGTTCATTTACTTATTGAAAAGGCATGTGAAGATCATAATTATGAAGTTATTAAATGGATATATGAAAACCTACATGTCTGCCATATAATAGATACCTTTGACTGTGCTATTGCCCATAAAGATCTACGTTTATATTGTTTGGGGTATACATTTATATACAACAGGATTGTACCCTATAAGTATCATCATTTAGATATTCTCATACTTTCAAGCCTACAACTCCTACATAAGGTGGCGGCCAAAGGATACTTAGATTTTATCCTAGAAACCTTAAAGTATGATCATAATATAGATAATTTAGATGTTATTCTAACACAAGCTGCAACATATAACCATAGAAAAATTTTAACCTATTTTATTCCTCAATCAACCTACGCACAAATAGAACAATGTTTGTTCGTGGCGATAAAAACAAAATCTTCCAAGAAAACCTTGAACTTACTACTGTCTCACCTAAACCTTTCCATCAAACTCATCCAAAAAATCAGCCAATATGTTGCCACTTTCAATTCAACAAATATAATAGGCATTCTGAGTATGAAGCGGAAAAAGAAGATATATTTGGATATCATATTGACAAAATTTGTAAAAAATGCTATTTTTAATAAATTTGTCGTTCGATGTATGGAGAGATTTTCTATAAACCCGGAAAGAATCGTCAAAATGGCTGCGCGTATAAATAAGATGATGTTAGTGAAAAAAATATCTGAACATGTTTGGAAAAATCATGCGGCTAGACTTAAACACCTTAAACATGCGGTACACACGATGAAGCATAAAGATGGGAAAAATAGACTCATGAACTTTATCTATGAACACTGCTATTACCATATGCAAGGGGAAGAAATTTTTAGCCTCGCAAGATTTTATGCAATCCATCATGCACCAAAGTTGTTCGACGTTTTTTATAATTGTTGTATCCTAGATACGATACGATTCAAAAGCCTTCTTTTAGATTGTTCACATATCATAGGTAAAAACGCTCATGATGCTACTAATATCAACATCGTGAACAAGTATATTGGCAACCTGTTTGCTATGGGAGTTCTTAGCAAAAAAGAAATCTTACAGGACTATCCATCCATCTATTCTAAACATTATATGCCTTAG
Protein
MFSLQNLCRKTLPDCKLPEFFDDYILQLLGLYWENHGTIQRAGNNCVLIQQHTLIPVNEALRIAASEENYEIVGLLLAWEGNLYYAIIGALEGNRYNLIRKYDDQIKDHHDILPFIDDPIIFHKCHIMRRCFFDCILYQAVKYSKFRVLLYFKYTLEDDLPLVHLLIEKACEDHNYEVIKWIYENLHVCHIIDTFDCAIAHKDLRLYCLGYTFIYNRIVPYKYHHLDILILSSLQLLHKVAAKGYLDFILETLKYDHNIDNLDVILTQAATYNHRKILTYFIPQSTYAQIEQCLFVAIKTKSSKKTLNLLLSHLNLSIKLIQKISQYVATFNSTNIIGILSMKRKKKIYLDIILTKFVKNAIFNKFVVRCMERFSINPERIVKMAARINKMMLVKKISEHVWKNHAARLKHLKHAVHTMKHKDGKNRLMNFIYEHCYYHMQGEEIFSLARFYAIHHAPKLFDVFYNCCILDTIRFKSLLLDCSHIIGKNAHDATNINIVNKYIGNLFAMGVLSKKEILQDYPSIYSKHYMP

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Similarity
Belongs to the asfivirus MGF 505 family.
Keywords
Complete proteome   Reference proteome   ANK repeat   Repeat  
Feature
chain  Protein MGF 505-1R
EMBL
AM712239    CAN10120.1    FN557520    CBH29122.1    KM102979    KX354450    + More
AJZ77058.1    AOO54340.1    KM262844    KP055815    AIY22212.1    AKO62703.1    AY261366    KM111294    AJL34037.1    KM111295    AJL34201.1    MH025916    MH025917    MH025918    MH025919    MH025920    AXB49251.1    AXB49425.1    AXB49597.1    AXB49770.1    AXB49941.1    AY261360    FR682468    CBW46685.1    MG939583    MG939587    MG939588    LS478113    AXZ95798.1    AXZ95986.1    AXZ96081.1    SPS73442.1    AY261363    U03762    AY261361    CBW46690.1    AXZ95803.1    AXZ95991.1    AXZ96086.1    SPS73447.1    AJZ77106.1    AOO54351.1    CAN10125.1    CBH29127.1    AIY22217.1    AKO62708.1    U02468    U18466    AJL34042.1    AJL34207.1    AXB49256.1    AXB49430.1    AXB49602.1    AXB49774.1    AXB49946.1    CAN10126.1    CBH29128.1    AM712240    CAN10375.1    KM262845    AIY22218.1    AIY22377.1    AJZ77065.1    AKO62709.1    AOO54353.1    CBW46692.1    AXZ95993.1    AXZ96088.1    SPS73449.1    AXZ95805.1    AJL34043.1    AJL34208.1    AXB49257.1    AXB49431.1    AXB49603.1    AXB49947.1    CBW46693.1    SPS73450.1    AXZ95806.1    AXZ95994.1    AXZ96089.1    CAN10376.1    AIY22378.1    CAN10127.1    CBH29129.1    AIY22219.1    AJZ77066.1    AKO62710.1    AOO54354.1    AXB49255.1    AXB49429.1    AXB49601.1    AXB49773.1    AXB49945.1    AJL34206.1    AJL34209.1    AXB49258.1    AXB49432.1    AXB49604.1    AXB49775.1    AXB49948.1    CBW46689.1    AXZ95802.1    AXZ95990.1    AXZ96085.1    SPS73446.1    CAN10124.1    AIY22216.1    AJZ77062.1    AKO62707.1    AOO54349.1    AJL34047.1    AXB49261.1    AXB49435.1    AXB49607.1    AXB49778.1    AXB49951.1    AJL34212.1    AJL34044.1    CBH29133.1    CBH29126.1    AJZ77055.1    AOO54359.1    CAN10131.1    CAN10380.1    AIY22382.1    AIY22223.1    AKO62714.1    CBW46697.1    AXZ95809.1    AXZ95997.1    AXZ96092.1    SPS73454.1    AJL34041.1    U03761    CBW46695.1    SPS73452.1    AKO62712.1    AOO54356.1    AJL34045.1    CAN10129.1    CBH29131.1    AIY22221.1    AJZ77061.1    CBW46694.1    AXZ95807.1    AXZ95995.1    AXZ96090.1    SPS73451.1    AJL34211.1    AXB49260.1    AXB49434.1    AXB49606.1    AXB49777.1    AXB49950.1   
Pfam
PF03158   DUF249
Interpro
IPR004858   MGF_505
IPR036770   Ankyrin_rpt-contain_sf
SUPFAM
SSF48403   SSF48403
Gene 3D
PDB
3J6H     E-value=5.15045,     Score=70

Ontologies

Subcellular Location

From MSLVP
Cytoplasm

Topology

Length:
531
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.867089999999999
Exp number, first 60 AAs:
0.0002
Total prob of N-in:
0.03632
outside
1  -  531
 
 

Population Genetic Test Statistics

Pi
0.0899646
Theta
0.1320841
Tajima's D
-1.2086392
CLR
0.249041
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
AKO62703.1
China_AnhuiXCGQ_2018    
China_ASFV-SY18_2018 Protein
AKO62703.1
Poland_Pol16_20186_o7_2016-2017    
Poland_Pol16_20538_o9_2016-2017 Protein
CAN10120.1
Poland_Pol16_20540_o10_2016-2017 Protein
CAN10120.1
Poland_Pol16_29413_o23_2016-2017 Protein
CAN10120.1
Poland_Pol17_03029_C201_2016-2017    
Poland_Pol17_04461_C210_2016-2017    
Poland_Pol17_05838_C220_2016-2017 Protein
CAN10120.1
Poland_ASFV_POL_Podlaskie_2015 Protein
CAN10120.1
Uganda_R8_2015    
Uganda_R7_2015    
Uganda_R25_2015    
Uganda_N10_2015    
Uganda_R35_2015    
Estonia_2014    
Italy_26544_OG10_2010 Protein
AJZ77058.1
Italy_47_Ss_2008_2008 Protein
AOO54340.1
Portugal_OURT_88.3_1988    
Spain_E75_1975 Protein
CBH29122.1
Russia_Georgia_2007    
Kenya_Tk1_2005    
Kenya_Bus_2006    
Russia_Odintsovo_2014 Protein
CAN10120.1
Portugal_L60_1960 Protein
AIY22212.1
Portugal_NHV_1968    
Russia_Kashino_2013 Protein
CAN10120.1
Benin_1997 Protein
CAN10120.1
South_Africa_KNP_Pretorisuskop_1996    
South_Africa_MGR_Mkuzi_1979    
Malawi_Lil_1983    
Kenya_1950    
Namibia_Warthog_1980    
South_Africa_Warmbaths_1987    
Malawi_Tengani_1962    
China_HLJ_2018    
China_LN_2018    
China_wbBS01_2018    
Ukraine_Kyiv_2014    
Belgium_Etalle_wb_2018    
Lithuania_LT14_2014    
South_Africa_1985    
South_Africa_2_2008    
Zambia_LIV_1983    
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