Strain

Italy_26544_OG10_2010 (Region: Sardinian,Italy; Strain: 26544/OG10; Date: 2010)

Gene

D205R

Description

Annotated in NCBI, pD205R

Location

KM102979.1(+):138766-139383

GenBank Accession

AJZ77130.1

Full name

Putative DNA-directed RNA polymerase subunit 5 homolog

CDS

ATGGCCATGCAAAAGTTATTTACGTATATTTACGAATTTATTGAATATCGTAAGATGGTGCTGTTGGAAGAAAAGGTACCATATGATAAGTTTGTTCAAATGGTACTTAATACAGGATTTTTTCGTATTAACGCGGAGACGCTGAATCACGGAATCGTGTCCGTGTTTATCTTTGGAGCAAATGGCAAGTACGTTCACCACGGAGGCGACATGAGAACGCTTTTAACGAATACGCTTAATGAAAAAAAACATTATGAAGAATTAATTTTAATCGTTGATAAGCCCGTTTTAAGCAAAAAAAATATTTTAGATATAATCGTCGAGCAGCGGGCTGCAAATCCCACGATTGTAATAAACATATATCCCTACCACCTGTTCTGCATTAACATTTCCAAGGTGAGTGCCATTCCTAAACATAAACTAATTACTCAGGAGGAGGCGCAGGAGTTTTTAGGTCGCGAATATCTGCAGCCGCAGGACCTCATGCAAATTAGCGCGTCAGACCCCCCGGTGGTCTGGCTGGGAGGAAGACCGGGAGACTTTGTGCAAATTGAGCGGCCCTCAGAGACAGCTATGCACGCTGTTGTTATCCGCTTTATCACCAAGTCCAAAATTTGA

Protein

MAMQKLFTYIYEFIEYRKMVLLEEKVPYDKFVQMVLNTGFFRINAETLNHGIVSVFIFGANGKYVHHGGDMRTLLTNTLNEKKHYEELILIVDKPVLSKKNILDIIVEQRAANPTIVINIYPYHLFCINISKVSAIPKHKLITQEEAQEFLGREYLQPQDLMQISASDPPVVWLGGRPGDFVQIERPSETAMHAVVIRFITKSKI

Function

Component of the DNA-dependent RNA polymerase that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.

Subunit

Component of the RNA polymerase that consists of at least 6 subunits.

Similarity

Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.

Keywords

Complete proteome DNA-directed RNA polymerase Transcription Reference proteome

Feature

chain Putative DNA-directed RNA polymerase subunit 5 homolog

Uniprot

A0A1C6ZY42 A9JL82 D4I5U5 A9JM16 E0WM58 A0A0A1E0C1 + More
P0C9B5 Q65181 P0C9B4 Q65224 A0A0C5B289 P0C9B6 A0A0C5B2P4 A0A2Z5DGU1

Pubmed

18198370 21470447 25406173 26618713 11831707 8021596 + More
25645905

EMBL

KM102979 KX354450 AJZ77130.1 AOO54468.1 AM712239 CAN10207.1 + More
FN557520 CBH29208.1 AM712240 CAN10457.1 FR682468 CBW46774.1 KM262844 KM262845 KP055815 MG939583 MG939588 LS478113 AIY22299.1 AIY22457.1 AKO62789.1 AXZ95882.1 AXZ96165.1 SPS73531.1 AY261366 U18466 AY261363 X71982 AY261361 KM111294 AJL34121.1 AY261360 KM111295 MH025916 MH025917 MH025918 MH025920 AJL34286.1 AXB49337.1 AXB49511.1 AXB49683.1 AXB50027.1 MH025919 AXB49854.1

Proteomes

UP000117635 UP000266411 UP000130745 UP000101090 UP000108903 UP000141072 + More
UP000110401 UP000142390 UP000241813 UP000000858 UP000000624 UP000000859 UP000000860 UP000105860 UP000000861 UP000101566

Pfam

PF01191 RNA_pol_Rpb5_C

Interpro

IPR014381   DNA_RNA_pol_RPB5_euk/virus
IPR039531   Rpb5-like
IPR000783   RNA_pol_subH/Rpb5_C
IPR035913   RPB5-like_sf

SUPFAM

SSF55287 SSF55287

Gene 3D

3.90.940.20

ProteinModelPortal

A0A1C6ZY42 A9JL82 D4I5U5 A9JM16 E0WM58 A0A0A1E0C1 + More
P0C9B5 Q65181 P0C9B4 Q65224 A0A0C5B289 P0C9B6 A0A0C5B2P4 A0A2Z5DGU1

PANTHER

PTHR10535

PDB

6DRD E-value=8.21715e-08, Score=132

Ontologies

KEGG

vg:22220337

GO

GO:0003899  F:DNA-directed 5'-3' RNA polymerase activity
GO:0006351  P:transcription, DNA-templated
GO:0003677  F:DNA binding

Subcellular Location

From MSLVP

Multi-Pass Membrane

Topology

Length:

205

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.799359999999999

Exp number, first 60 AAs:

0.59488

Total prob of N-in:

0.14075

outside

1 - 205

Population Genetic Test Statistics

Pi

0.0345847

Theta

0.0409595

Tajima's D

-0.6887604

CLR

0

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein	AKO62789.1
China_AnhuiXCGQ_2018	Protein	AYW34079.1
China_ASFV-SY18_2018	Protein	AKO62789.1
Poland_Pol16_20186_o7_2016-2017	Protein	AXZ95882.1
Poland_Pol16_20538_o9_2016-2017	Protein	CAN10207.1
Poland_Pol16_20540_o10_2016-2017	Protein	CAN10207.1
Poland_Pol16_29413_o23_2016-2017	Protein	CAN10207.1
Poland_Pol17_03029_C201_2016-2017	Protein	CAN10207.1
Poland_Pol17_04461_C210_2016-2017	Protein	AXZ96165.1
Poland_Pol17_05838_C220_2016-2017	Protein	CAN10207.1
Poland_ASFV_POL_Podlaskie_2015	Protein	CAN10207.1
Uganda_R8_2015	Protein	AXB49337.1
Uganda_R7_2015	Protein	AXB49511.1
Uganda_R25_2015	Protein	AXB49683.1
Uganda_N10_2015	Protein	AXB49854.1
Uganda_R35_2015	Protein	AXB50027.1
Estonia_2014	Protein	SPS73531.1
Italy_26544_OG10_2010	Protein	AJZ77130.1
Italy_47_Ss_2008_2008	Protein	AOO54468.1
Portugal_OURT_88.3_1988	Protein	CAN10457.1
Spain_E75_1975	Protein	CBH29208.1
Russia_Georgia_2007	Protein	CBW46774.1
Kenya_Tk1_2005	Protein	AJL34121.1
Kenya_Bus_2006	Protein	AJL34286.1
Russia_Odintsovo_2014	Protein	CAN10207.1
Portugal_L60_1960	Protein	AIY22299.1
Portugal_NHV_1968	Protein	AIY22457.1
Russia_Kashino_2013	Protein	CAN10207.1
Benin_1997	Protein Protein	CAN10207.1 CAN10207.1
South_Africa_KNP_Pretorisuskop_1996
South_Africa_MGR_Mkuzi_1979	Protein	CAN10207.1
Malawi_Lil_1983	Protein	CAN10207.1
Kenya_1950	Protein	CAN10207.1
Namibia_Warthog_1980	Protein	CAN10207.1
South_Africa_Warmbaths_1987	Protein	CAN10207.1
Malawi_Tengani_1962	Protein	CAN10207.1
China_HLJ_2018	Protein	QBH90596.1
China_LN_2018	Protein	QBH90781.1
China_wbBS01_2018	Protein	QDL88139.1
Ukraine_Kyiv_2014	Protein	QED21711.1
Belgium_Etalle_wb_2018	Protein	QED90551.1
Lithuania_LT14_2014	Protein	QEY87914.1
South_Africa_1985	Protein	QGM12930.1
South_Africa_2_2008	Protein	QGM12856.1
Zambia_LIV_1983	Protein	QGM12748.1

Sequence