Strain

Russia_Georgia_2007 (Region: Russia; Strain: Georgia 2007/1; Date: 2007)

Gene

L83L

Description

Annotated in NCBI, product contains farnesylation signal

Location

FR682468.1(-):3917-4162

GenBank Accession

CBW46646.1

Full name

Protein L83L

Sequence

CDS

ATGGATACTTCTTTGAAAAATAATGATGGAGCTTTAGAAGCTGATAACAAAAATTATCAAGATTATAGAGCTGAGCCTGATAAAACAAACGATGTATTAGATGTTACTAAATATAATTCAATGGTAGATTGTTGCCATAAAAATTATTCAACGTTTACATCTGAATGGTATATTAATGAAAGAAAATATAATGATGTTCCAGAAGGACCAAAAAAAGCAGTTGTGCATCGATGCACAATATTATAA

Protein

MDTSLKNNDGALEADNKNYQDYRAEPDKTNDVLDVTKYNSMVDCCHKNYSTFTSEWYINERKYNDVPEGPKKAVVHRCTIL

Summary

Function

May subvert the host innate immune response by interacting with host IL1B and interfering with its function.

Subunit

Interacts with host IL1B.

Similarity

Belongs to the asfivirus L83L family.

Keywords

Complete proteome Early protein Host cytoplasm Host-virus interaction Reference proteome

Feature

chain Protein L83L

Uniprot

E0WMB8 A0A385KMD1 D4I5I9 A9JLH7 A0A0A1DY73 Q65132 + More
A9JKR2 P0CAK9 P0CAK8 P0CAK7 A0A0C5AW73 A0A0C5AWH8 P0CAK6

Pubmed

21470447 18198370 25406173 26618713 11831707 29605728 + More
25645905

EMBL

FR682468 CBW46646.1 MG939583 MG939586 MG939587 MG939588 + More
AXZ95771.1 AXZ95951.1 AXZ95968.1 AXZ96063.1 FN557520 CBH29102.1 AM712240 CAN10353.1 KM262844 KM262845 KP055815 KX354450 AIY22192.1 AIY22355.1 AKO62687.1 AOO54312.1 U18466 AM712239 CAN10101.1 AY261366 AY261363 AY261361 KM111294 AJL34009.1 KM111295 MH025916 MH025917 MH025918 MH025919 MH025920 AJL34174.1 AXB49223.1 AXB49396.1 AXB49570.1 AXB49742.1 AXB49913.1 AY261360

Proteomes

UP000141072 UP000101090 UP000108903 UP000110401 UP000142390 UP000241813 + More
UP000266411 UP000000624 UP000130745 UP000000858 UP000000859 UP000000860 UP000105860 UP000101566 UP000000861

PRIDE

Q65132

ProteinModelPortal

E0WMB8 A0A385KMD1 D4I5I9 A9JLH7 A0A0A1DY73 Q65132 + More
A9JKR2 P0CAK9 P0CAK8 P0CAK7 A0A0C5AW73 A0A0C5AWH8 P0CAK6

Ontologies

KEGG

vg:22220395

GO:0030430 C:host cell cytoplasm
GO:0016032 P:viral process

Subcellular Location

From MSLVP

Host nucleus > host nucleolus. Host cytoplasm. Secreted.

From Uniprot

Host cytoplasm

Topology

Length:

Number of predicted TMHs:

Exp number of AAs in TMHs:

Exp number, first 60 AAs:

Total prob of N-in:

0.42110

outside

1 - 81

Population Genetic Test Statistics

0.0750329

Theta

0.1328724

Tajima's D

-1.5431542

CLR

13.753192

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein	AKO62687.1
China_AnhuiXCGQ_2018	Protein	AYW33973.1
China_ASFV-SY18_2018	Protein	AKO62687.1
Poland_Pol16_20186_o7_2016-2017	Protein	AXZ95771.1
Poland_Pol16_20538_o9_2016-2017	Protein	CAN10353.1
Poland_Pol16_20540_o10_2016-2017	Protein	CAN10353.1
Poland_Pol16_29413_o23_2016-2017	Protein	AXZ95951.1
Poland_Pol17_03029_C201_2016-2017	Protein	AXZ95968.1
Poland_Pol17_04461_C210_2016-2017	Protein	AXZ96063.1
Poland_Pol17_05838_C220_2016-2017	Protein	CAN10353.1
Poland_ASFV_POL_Podlaskie_2015	Protein	CAN10353.1
Uganda_R8_2015	Protein	AXB49223.1
Uganda_R7_2015	Protein	AXB49396.1
Uganda_R25_2015	Protein	AXB49570.1
Uganda_N10_2015	Protein	AXB49742.1
Uganda_R35_2015	Protein	AXB49913.1
Estonia_2014
Italy_26544_OG10_2010	Protein	CAN10353.1
Italy_47_Ss_2008_2008	Protein	AOO54312.1
Portugal_OURT_88.3_1988	Protein Protein	CAN10353.1 CAN10353.1
Spain_E75_1975	Protein	CBH29102.1
Russia_Georgia_2007	Protein	CBW46646.1
Kenya_Tk1_2005	Protein	AJL34009.1
Kenya_Bus_2006	Protein	AJL34174.1
Russia_Odintsovo_2014
Portugal_L60_1960	Protein	AIY22192.1
Portugal_NHV_1968	Protein	AIY22355.1
Russia_Kashino_2013	Protein	CAN10353.1
Benin_1997	Protein	CAN10101.1
South_Africa_KNP_Pretorisuskop_1996	Protein	CAN10353.1
South_Africa_MGR_Mkuzi_1979	Protein	CAN10353.1
Malawi_Lil_1983
Kenya_1950
Namibia_Warthog_1980	Protein	CAN10353.1
South_Africa_Warmbaths_1987	Protein	CAN10353.1
Malawi_Tengani_1962	Protein	CAN10353.1
China_HLJ_2018	Protein	QBH90469.1
China_LN_2018	Protein	QBH90654.1
China_wbBS01_2018	Protein	QDL88013.1
Ukraine_Kyiv_2014	Protein	QED21543.1
Belgium_Etalle_wb_2018	Protein	QED90427.1
Lithuania_LT14_2014	Protein	QEY87786.1
South_Africa_1985
South_Africa_2_2008
Zambia_LIV_1983