Strain

Spain_E75_1975 (Region: Spain;  Strain: E75;  Date: 1975)

Gene

BA71V-EP153R

Description

Annotated in NCBI,  non-essential

Location

FN557520.1(+):66350-66811

GenBank Accession

CBH29158.1

Full name

Lectin-like protein EP153R      

CDS

ATGTATTTTAAGAAAAAATACATCGGTCTTATTGATAAGAACTGTGAAAAAAAAATATTAGATGATTCTAGTACAATAAAAATTTGTTACATATTAATTGGAATATTGATTGGAACTAATATGATAACTCTTATTTATAATTTCATATTCTGGGATAATTATATAAAATGTTACCGAAATAATGATAAAATGTTTTACTGTCCTAATGATTGGGTTGGATATAATAATATTTGTTACTATTTTAGTAATGGTAGTTTTTCTAAAAATTATACAGCTGCTAGTAATTTTTGTAGACAATTAAATGGTACACTTGCTAATAATGATACTAATTTATTAAATCTAACTAAAATATATAATAATCAATCTATGTATTGGGTTAACAATACGGTAATATTACGTGGTGATAATAAATATAGTCAAAAAGTTAACTATACAGATTTATTATTTATTTGTGGTAAATAA

Protein

MYFKKKYIGLIDKNCEKKILDDSSTIKICYILIGILIGTNMITLIYNFIFWDNYIKCYRNNDKMFYCPNDWVGYNNICYYFSNGSFSKNYTAASNFCRQLNGTLANNDTNLLNLTKIYNNQSMYWVNNTVILRGDNKYSQKVNYTDLLFICGK

Function

Participates to viral hemadsorption, which may help viral spread (PubMed:10639320). Reduces the transactivating activity of host TP53, thus inhibiting apoptosis (PubMed:15262504). Non-essential for virus growth in swine macrophage cell cultures (By similarity).
Participates to viral hemadsorption, which may help viral spread. Reduces the transactivating activity of host TP53, thus inhibiting apoptosis (By similarity). Non-essential for virus growth in swine macrophage cell cultures (By similarity).
Participates to viral hemadsorption, which may help viral spread. Reduces the transactivating activity of host TP53, thus inhibiting apoptosis (By similarity). Non-essential for virus growth in swine macrophage cell cultures (PubMed:10573162).

Similarity

Belongs to the asfivirus lectin-like protein family.

Keywords

Complete proteome   Glycoprotein   Host membrane   Host-virus interaction   Lectin   Membrane   Modulation of host cell apoptosis by virus   Reference proteome   Signal-anchor   Transmembrane   Transmembrane helix   Late protein  

Feature

chain  Lectin-like protein EP153R

Uniprot

Q8JSP0   A9JL06   D4I5P5   Q77Z14   Q65150   O89333   + More
Q4TZL7   O89332   A0A0A7W6V6   O89336   A0A0C5B2I5   A0A0A7W6T2   A0A0C5B248   O89329   O89335   A0A0A7W576   O89334   P0CA64   A0A0A7W4S6   A0A0A7W6S0   O89331   A0A0A7W4Q4   A0A0A7W520   A0A0A7WCA2   O89337   P0CA65   O89330   O89338   P0CA63   E0WMJ5   A0A0A7W5A0  

Pubmed

19729182    18198370    10573162    25406173    25524164    26618713    + More
11831707    10639320    15262504    25645905    21470447   

EMBL

AF481876    AAM90853.1    AM712239    CAN10157.1    FN557520    CBH29158.1    + More
AF017030    AF017031    AF017032    AY463913    AY463915    AY463916    DQ026264    DQ026266    DQ026267    DQ026268    DQ026269    DQ026270    KM262844    KM609334    KM609337    KM609350    KM609351    KM609352    KM609355    KM102979    KP055815    KX354450    AAC28417.1    AAS45763.1    AAY44916.1    AAY44920.1    AAY44922.1    AAY44925.1    AAY44926.1    AAY44928.1    AIY22248.1    AJB28357.1    AJB28363.1    AJB28385.1    AJB28387.1    AJB28389.1    AJB28393.1    AJZ77151.1    AKO62739.1    AOO54389.1    U18466    AF017034    AAC28419.1    DQ026265    AAY44918.1    AF017033    AAC28418.1    KM609361    AJB28404.1    AF017037    AAC28422.1    KM111295    MH025916    MH025917    MH025918    MH025919    MH025920    AJL34236.1    AXB49286.1    AXB49460.1    AXB49632.1    AXB49803.1    AXB49976.1    KM609340    KM609343    KM609344    KM609345    AJB28367.1    AJB28372.1    AJB28374.1    AJB28376.1    KM111294    AJL34071.1    AF017027    AAC28412.1    AY261363    AF017036    AF050111    KM609346    KM609347    AJB28377.1    AJB28379.1    AF017035    KM609354    AAC28420.1    AJB28391.1    AY261361    KM609348    AJB28381.1    KM609335    AJB28359.1    AF017029    AAC28414.1    KM609336    AJB28361.1    KM609359    AJB28400.1    KM609349    AJB28383.1    AF017038    AAC28423.1    AY261366    AF017028    AAC28413.1    AF017039    KM609339    KM609341    KM609356    KM609357    AAC28424.1    AJB28365.1    AJB28368.1    AJB28395.1    AJB28397.1    AY261360    FR682468    CBW46723.1    KM609342    KM609360    KM609362    KM609363    KU752730    KU752731    KU752732    KU752733    KU752734    KU752735    KU752736    KU752737    KU752738    KU752739    KU752740    KU752741    KU752742    KU752743    KU752744    KU752745    KU752746    KU752747    KU752748    KU752749    KU752750    KU752751    KU752752    KU752753    KU752754    KU752755    KU752756    KU752757    KU752758    KU752759    KU752760    KU752761    KU752762    KU752763    KU752764    KU752765    KU752766    KU752767    KU752768    KU752769    KU752770    KU752771    KU752772    KU752773    KU752774    KU752775    KU752776    KU752777    KU752778    KU752779    KU752780    KU752781    KU752782    KU752783    KU752784    KU752785    KU752786    KU752787    KU752788    KU752789    KU752790    KU752791    KU752792    KU752793    KU752794    KU752795    KU752796    MG939583    MG939587    MG939588    LS478113    AJB28370.1    AJB28402.1    AJB28406.1    AJB28408.1    ANC98852.1    ANC98853.1    ANC98854.1    ANC98855.1    ANC98856.1    ANC98857.1    ANC98858.1    ANC98859.1    ANC98860.1    ANC98861.1    ANC98862.1    ANC98863.1    ANC98864.1    ANC98865.1    ANC98866.1    ANC98867.1    ANC98868.1    ANC98869.1    ANC98870.1    ANC98871.1    ANC98872.1    ANC98873.1    ANC98874.1    ANC98875.1    ANC98876.1    ANC98877.1    ANC98878.1    ANC98879.1    ANC98880.1    ANC98881.1    ANC98882.1    ANC98883.1    ANC98884.1    ANC98885.1    ANC98886.1    ANC98887.1    ANC98888.1    ANC98889.1    ANC98890.1    ANC98891.1    ANC98892.1    ANC98893.1    ANC98894.1    ANC98895.1    ANC98896.1    ANC98897.1    ANC98898.1    ANC98899.1    ANC98900.1    ANC98901.1    ANC98902.1    ANC98903.1    ANC98904.1    ANC98905.1    ANC98906.1    ANC98907.1    ANC98908.1    ANC98909.1    ANC98910.1    ANC98911.1    ANC98912.1    ANC98913.1    ANC98914.1    ANC98915.1    ANC98916.1    ANC98917.1    ANC98918.1    AXZ95832.1    AXZ96020.1    AXZ96115.1    SPS73480.1   

Proteomes

UP000130745    UP000101090    UP000117635    UP000142390    UP000241813    UP000266411    + More
UP000000624    UP000101566    UP000105860    UP000000859    UP000000860    UP000000858    UP000000861    UP000141072   

PRIDE

Q65150    P0CA65    P0CA63   

Pfam

PF05473   UL45

Interpro

IPR016187   CTDL_fold
IPR008646   Herpes_UL45-like
IPR016186   C-type_lectin-like/link_sf

SUPFAM

SSF56436   SSF56436

Gene 3D

3.10.100.10    

ProteinModelPortal

Q8JSP0   A9JL06   D4I5P5   Q77Z14   Q65150   O89333   + More
Q4TZL7   O89332   A0A0A7W6V6   O89336   A0A0C5B2I5   A0A0A7W6T2   A0A0C5B248   O89329   O89335   A0A0A7W576   O89334   P0CA64   A0A0A7W4S6   A0A0A7W6S0   O89331   A0A0A7W4Q4   A0A0A7W520   A0A0A7WCA2   O89337   P0CA65   O89330   O89338   P0CA63   E0WMJ5   A0A0A7W5A0  

PDB

5MGT     E-value=0.938138,     Score=69