Strain

South_Africa_KNP_Pretorisuskop_1996 (Region: South Africa, Kruger National Park; Strain: Pretorisuskop/96/4; Date: 1996)

Gene

pE199L

Description

Annoated by sequence mapping, Putative transmembrane protein

Location

AY261363.1(-):166816-167415

GenBank Accession

CAN10229.1

Full name

Cysteine-rich protein E199L

CDS

ATGTCTTGCATGCCAGTTTCCACGAAATGCAATGATATTTGGGTCGACTTTAGCTGTACAGGCCCTTCGATTTCCGAGCTGCAAAAAAAGGAGCCCAAGGCCTGGGCCGCTATTTTACGCTCGCATACAAATCAACAAACGGCGGAGGATGACACTATTATTGGGAGCATATGCGATAAACAGGGATTGTGCTCAAAGGATGAGTATGCGTATAGCCAGTATTGTGCCTGTGTGAACTCCGGCACCTTATGGGCTGAATGTGCGTTTGCTCCGTGCAATGGAAATAAAAATGCCTATAAAACGACGGAGCAAAGAAATATTTTGACCAACAAGCAGTGCCCCTCCGGACTCACCATATGTCAGAACATTGCAGAATACGGAGGCTCGGGCAATATTTCCGATCTATACCAAAATTTCAACTGCAACAGCGTTATAAATACGTTTTTAATTAATGTGATGAATCATCCTTTTTTAACCCTTATATTAATCATTTTGATTCTTATAATTATTTACCGTTTGATGTCTTCCAGTGGGGGTAAACACAATGACGATAAGTTGCCCCCTCCATCTCTTATTTTTTCAAACCTAAACAATTTTTAA

Protein

MSCMPVSTKCNDIWVDFSCTGPSISELQKKEPKAWAAILRSHTNQQTAEDDTIIGSICDKQGLCSKDEYAYSQYCACVNSGTLWAECAFAPCNGNKNAYKTTEQRNILTNKQCPSGLTICQNIAEYGGSGNISDLYQNFNCNSVINTFLINVMNHPFLTLILIILILIIIYRLMSSSGGKHNDDKLPPPSLIFSNLNNF

Similarity

Belongs to the asfivirus E199L family.

Keywords

Complete proteome Glycoprotein Host membrane Late protein Membrane Reference proteome Transmembrane Transmembrane helix Virion

Feature

chain Cysteine-rich protein E199L

Uniprot

E0WM79 A0A2X0RU26 A0A385KM81 D4I5F3 A0A0A1DY42 A9JLC0 + More
A0A0N7CR51 Q65198 A0A1C6ZY44 A9JM57 A0A0A1E184 P0CA95 P0CA96 A0A0C5AZI6 A0A0C5AZ15 Q65242 P0CA94

Pubmed

21470447 25406173 18198370 26618713 11831707 25645905 + More
8021596 8609490

EMBL

FR682468 CBW46795.1 MG939588 LS478113 AXZ96184.1 SPS73552.1 + More
MG939583 AXZ95901.1 FN557520 CBH29229.1 KM262844 AIY22320.1 AM712239 CAN10229.1 KP055815 AKO62810.1 U18466 KM102979 KX354450 AJZ77132.1 AOO54499.1 AM712240 CAN10478.1 KM262845 AIY22478.1 AY261363 AY261366 KM111295 MH025916 MH025917 MH025918 MH025919 MH025920 AJL34307.1 AXB49358.1 AXB49532.1 AXB49704.1 AXB49875.1 AXB50048.1 KM111294 AJL34142.1 X71982 AY261361 AY261360

Proteomes

UP000141072 UP000101090 UP000142390 UP000130745 UP000241813 UP000000624 + More
UP000117635 UP000266411 UP000108903 UP000110401 UP000000859 UP000000858 UP000101566 UP000105860 UP000000860 UP000000861

PRIDE

Q65242

ProteinModelPortal

E0WM79 A0A2X0RU26 A0A385KM81 D4I5F3 A0A0A1DY42 A9JLC0 + More
A0A0N7CR51 Q65198 A0A1C6ZY44 A9JM57 A0A0A1E184 P0CA95 P0CA96 A0A0C5AZI6 A0A0C5AZ15 Q65242 P0CA94

PDB

6A8T E-value=7.2512, Score=63

Ontologies

KEGG

vg:22220358

GO

GO:0016021  C:integral component of membrane
GO:0019012  C:virion
GO:0033644  C:host cell membrane

Subcellular Location

From MSLVP

Single-Pass Membrane

From Uniprot

Virion Found in cytoplasmic viral factories during assembly. With evidence from 1 publications.
Host membrane Found in cytoplasmic viral factories during assembly. With evidence from 1 publications.

Topology

Length:

199

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.13086

Exp number, first 60 AAs:

0

Total prob of N-in:

0.88975

inside

1 - 147

TMhelix

148 - 170

outside

171 - 199

Population Genetic Test Statistics

Pi

0.0283783

Theta

0.0386839

Tajima's D

-1.0719345

CLR

0.239661

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein	AKO62810.1
China_AnhuiXCGQ_2018	Protein	AYW34100.1
China_ASFV-SY18_2018	Protein	AKO62810.1
Poland_Pol16_20186_o7_2016-2017	Protein	AXZ95901.1
Poland_Pol16_20538_o9_2016-2017	Protein	CAN10229.1
Poland_Pol16_20540_o10_2016-2017	Protein	CAN10229.1
Poland_Pol16_29413_o23_2016-2017	Protein	CAN10229.1
Poland_Pol17_03029_C201_2016-2017	Protein	CAN10229.1
Poland_Pol17_04461_C210_2016-2017	Protein	AXZ96184.1
Poland_Pol17_05838_C220_2016-2017	Protein	CAN10229.1
Poland_ASFV_POL_Podlaskie_2015	Protein	CAN10229.1
Uganda_R8_2015	Protein	AXB49358.1
Uganda_R7_2015	Protein	AXB49532.1
Uganda_R25_2015	Protein	AXB49704.1
Uganda_N10_2015	Protein	AXB49875.1
Uganda_R35_2015	Protein	AXB50048.1
Estonia_2014	Protein	SPS73552.1
Italy_26544_OG10_2010	Protein	AJZ77132.1
Italy_47_Ss_2008_2008	Protein	AOO54499.1
Portugal_OURT_88.3_1988	Protein	CAN10478.1
Spain_E75_1975	Protein	CBH29229.1
Russia_Georgia_2007	Protein	CBW46795.1
Kenya_Tk1_2005	Protein	AJL34142.1
Kenya_Bus_2006	Protein	AJL34307.1
Russia_Odintsovo_2014	Protein	CAN10229.1
Portugal_L60_1960	Protein	AIY22320.1
Portugal_NHV_1968	Protein	AIY22478.1
Russia_Kashino_2013	Protein	CAN10229.1
Benin_1997	Protein Protein	CAN10229.1 CAN10229.1
South_Africa_KNP_Pretorisuskop_1996	Protein	CAN10229.1
South_Africa_MGR_Mkuzi_1979	Protein	CAN10229.1
Malawi_Lil_1983	Protein	CAN10229.1
Kenya_1950	Protein	CAN10229.1
Namibia_Warthog_1980	Protein	CAN10229.1
South_Africa_Warmbaths_1987	Protein	CAN10229.1
Malawi_Tengani_1962	Protein	CAN10229.1
China_HLJ_2018	Protein	QBH90617.1
China_LN_2018	Protein	QBH90802.1
China_wbBS01_2018	Protein	QDL88160.1
Ukraine_Kyiv_2014	Protein	QED21742.1
Belgium_Etalle_wb_2018	Protein	QED90572.1
Lithuania_LT14_2014	Protein	QEY87935.1
South_Africa_1985	Protein	CAN10229.1
South_Africa_2_2008	Protein	CAN10229.1
Zambia_LIV_1983	Protein	CAN10229.1

Sequence