Strain

Zambia_LIV_1983 (Region: Zambia; Strain: LIV_5_40; Date: 1983)

Gene

pEP364R

Description

Annotated in NCBI, EP364R

Location

MN318203.1(+):71334-72464

GenBank Accession

QGM12721.1

Full name

ERCC4 domain-containing protein EP364R + More

CDS

ATGTATTTTCTACTACCAGATCATCGAGAACATCATGTGTTTCCTTTTCTTACAACCGATTTTCATCACATGCATCAAAATCCTATACAAAAAAATCAAGCTCTCCTACAAATCAAACAGCTTTTTACTGGAGATTATCTCATCTGCAAAAGCCCTTCTACCATTCTGGCCTGTATTGTACGAAAAACCTACAAAGACTTTGCGGCTTCTTTGTACGATGGACGTTATACAAATCGCCAAAAAATGCTATCGCTGCGAGAACAAACCAACTGTCAACTTTATTTTTTTGTACAAGGCCCGGCATTCCCTATCCCTCAAAAAAAAATTATTCACGTTGCCTATGCAAGCATTATTACTGCTATGTCGCATCTTATGGTTACAGATCATATTTTTGTCATTCAAACGAAAAATGTGGCCCATACTTCCCAAAAGCTTATGCAGCTTTTTTATGCCTTTTCTATGGAAATGGTGTGCGTCGTTCCCACCTCCCTCACCCCCACGGATGTACAGCTATGCATCAAGCTATGGTCTTCTCTTTCTGGTATTTCAGGCGTGTTACGTACAATCTTGGCAAATACTTGTTCCGTACCTCATTTGGTTACTGGAAAGCTTTCATCGCAGAATATTGTTCAGTTACAAACTCCCTCCAACCGGCCATTCCCCAAAAAAGTACAACGTATGCTTATATGCATTACCAAAGGAAATATGGAGTTACAAATACAATTGCTCTCGGGGGTTCCCAATATCGGGAAAAAATTACCTGCCGAAATTTTACAAGATCATGCGCTTCTTTTTTTTCTATATCAGCCCGTACAATGCTTGGCAAATATACAAATTGTTCAAAAAACCCGTACGATTATGTTGGGAATATACCGAGCCAAAGCGATTCATTATTTTTTATACTGGTGTGGGTCTGCCCATGTATCCGATGTTACCCAAAATATCACAGAGGCGTCGCGGCCCGCAACGCAACACAGCCCGCTGCAACGCAGCCATTGCACGAAGTATCAGATGTTGTATCAACTATTGCATCAGATACATCCTCACCCGTACGGCATCAAACATTATCTATACAAAAGTCATTGTACACAGCCTGATGTTAATAATTCACTACATCTAAAGAAATGTTAA

Protein

MYFLLPDHREHHVFPFLTTDFHHMHQNPIQKNQALLQIKQLFTGDYLICKSPSTILACIVRKTYKDFAASLYDGRYTNRQKMLSLREQTNCQLYFFVQGPAFPIPQKKIIHVAYASIITAMSHLMVTDHIFVIQTKNVAHTSQKLMQLFYAFSMEMVCVVPTSLTPTDVQLCIKLWSSLSGISGVLRTILANTCSVPHLVTGKLSSQNIVQLQTPSNRPFPKKVQRMLICITKGNMELQIQLLSGVPNIGKKLPAEILQDHALLFFLYQPVQCLANIQIVQKTRTIMLGIYRAKAIHYFLYWCGSAHVSDVTQNITEASRPATQHSPLQRSHCTKYQMLYQLLHQIHPHPYGIKHYLYKSHCTQPDVNNSLHLKKCX

Similarity

Belongs to the asfivirus EP364R family.

Keywords

Complete proteome Reference proteome

Feature

chain ERCC4 domain-containing protein EP364R

Uniprot

A0A5B8XDP7 A0A3S9JJH8 P0CAF7 E0WMJ7 A0A2X0RTV5 P0CAF9 + More
P0CAF8 A0A3Q9CZH3 A0A0C5BCN1 A0A2Z5DF02 A0A0C5BC74 P0CAF6 A9JL08 D4I5P7 A9JLS7 A0A0A1DXX9 Q65151 A0A3G1EUY8 A0A2E0EN87 A0A1X6WEZ8

Pubmed

30547827 21470447 25645905 18198370 25406173 26618713 + More
11831707 29337314

EMBL

MN194591 QED21623.1 MH910495 AZP54002.1 AY261361 FR682468 + More
CBW46725.1 MG939583 MG939587 MG939588 LS478113 AXZ95834.1 AXZ96022.1 AXZ96117.1 SPS73482.1 AY261366 AY261363 MH910496 AZP54181.1 KM111295 AJL34238.1 MH025916 MH025917 MH025918 MH025919 MH025920 AXB49288.1 AXB49462.1 AXB49634.1 AXB49805.1 AXB49978.1 KM111294 AJL34073.1 AY261360 AM712239 CAN10159.1 FN557520 CBH29160.1 AM712240 CAN10407.1 KM262844 KM262845 KM102979 KP055815 AIY22250.1 AIY22409.1 AJZ77081.1 AKO62741.1 U18466 KX354450 AOO54392.1 NZXR01000083 MAR56918.1 LT706986 SIP85889.1

Proteomes

UP000321214 UP000000860 UP000141072 UP000000858 UP000000859 UP000101566 + More
UP000105860 UP000000861 UP000130745 UP000101090 UP000108903 UP000110401 UP000117635 UP000142390 UP000241813 UP000000624 UP000266411 UP000201921

Pfam

PF02732 ERCC4

Interpro

IPR011335 Restrct_endonuc-II-like
IPR006166 ERCC4_domain

SUPFAM

SSF52980 SSF52980

ProteinModelPortal

A0A5B8XDP7 A0A3S9JJH8 P0CAF7 E0WMJ7 A0A2X0RTV5 P0CAF9 + More
P0CAF8 A0A3Q9CZH3 A0A0C5BCN1 A0A2Z5DF02 A0A0C5BC74 P0CAF6 A9JL08 D4I5P7 A9JLS7 A0A0A1DXX9 Q65151 A0A3G1EUY8 A0A2E0EN87 A0A1X6WEZ8

PDB

2BHN E-value=0.000690214, Score=101

Ontologies

KEGG

vg:22220289

GO

GO:0004518 F:nuclease activity
GO:0003677 F:DNA binding

Subcellular Location

From MSLVP

Nucleus

Topology

Length:

377

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.32501

Exp number, first 60 AAs:

0.01416

Total prob of N-in:

0.01527

Length:

376

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.33414

Exp number, first 60 AAs:

0.01422

Total prob of N-in:

0.01534

outside

1 - 377

outside

1 - 376

Population Genetic Test Statistics

Pi

0.0358913

Theta

0.0455105

Tajima's D

-1.0620399

CLR

0.251708

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971
China_AnhuiXCGQ_2018
China_ASFV-SY18_2018
Poland_Pol16_20186_o7_2016-2017
Poland_Pol16_20538_o9_2016-2017
Poland_Pol16_20540_o10_2016-2017
Poland_Pol16_29413_o23_2016-2017
Poland_Pol17_03029_C201_2016-2017
Poland_Pol17_04461_C210_2016-2017
Poland_Pol17_05838_C220_2016-2017
Poland_ASFV_POL_Podlaskie_2015
Uganda_R8_2015
Uganda_R7_2015
Uganda_R25_2015
Uganda_N10_2015
Uganda_R35_2015
Estonia_2014
Italy_26544_OG10_2010
Italy_47_Ss_2008_2008
Portugal_OURT_88.3_1988
Spain_E75_1975
Russia_Georgia_2007
Kenya_Tk1_2005	Protein	AJL34073.1
Kenya_Bus_2006
Russia_Odintsovo_2014
Portugal_L60_1960
Portugal_NHV_1968
Russia_Kashino_2013
Benin_1997
South_Africa_KNP_Pretorisuskop_1996
South_Africa_MGR_Mkuzi_1979
Malawi_Lil_1983
Kenya_1950
Namibia_Warthog_1980
South_Africa_Warmbaths_1987
Malawi_Tengani_1962
China_HLJ_2018
China_LN_2018
China_wbBS01_2018
Ukraine_Kyiv_2014
Belgium_Etalle_wb_2018
Lithuania_LT14_2014
South_Africa_1985
South_Africa_2_2008
Zambia_LIV_1983	Protein	QGM12721.1

Sequence