ASFVdb The African Swine Fever Virus Database
Strain
Ukraine_Kyiv_2014 (Region: Ukraine;  Strain: ASFV/Kyiv/2016/131;  Date: 2014)
Gene
EP364R
Description
Annotated in NCBI,  ASFV_Kyiv_2016_131_00087
GenBank Accession
Full name
ERCC4 domain-containing protein EP364R      
 

Sequence

CDS
ATGTATTTTCTAGTAGCAGATCATCGAGAACATCATGTGATTCCTTTTCTTAAAACCGATTTCCATCACATGCATCAAAATCCTATACAAAAAAATCAAGCTCTCCTAGAAATCAAACAGCTTTTTACTGGAGATTATCTCATCTGCAAAAGCCCTTCTACCATTCTGGCCTGTATTGAACGAAAAACCTACAAAGACTTTGCGGCTTCTTTGAAAGATGGACGTTATAAAAATCGCCAAAAAATGCTGTCGCTGCGAGAACAAACCAACTGTCAACTTTATTTTTTTGTAGAAGGCCCGGCATTTCCTAACCCTCAAAAAAAAATTAATCACGTTGCCTATGCAAGCATTATTACTGCTATGACGCATCTTATGGTTAGAGATCATATTTTTGTCATTCAAACGAAAAATGAGGCCCACAGTTCCCAAAAGCTTGTGCAGCTTTTTTATGCCTTTTCTAAGGAAATGGTGTGCGTCGTTCCCACCTCCCTCACCCCCCACGGATGA
Protein
MYFLVADHREHHVIPFLKTDFHHMHQNPIQKNQALLEIKQLFTGDYLICKSPSTILACIERKTYKDFAASLKDGRYKNRQKMLSLREQTNCQLYFFVEGPAFPNPQKKINHVAYASIITAMTHLMVRDHIFVIQTKNEAHSSQKLVQLFYAFSKEMVCVVPTSLTPHG

Summary

Catalytic Activity
L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine
Similarity
Belongs to the asfivirus EP364R family.
Keywords
Complete proteome   Reference proteome  
Feature
chain  ERCC4 domain-containing protein EP364R
EMBL
MN194591    QED21623.1    FR682468    CBW46725.1    MG939583    MG939587    + More
MG939588    LS478113    AXZ95834.1    AXZ96022.1    AXZ96117.1    SPS73482.1    MH910495    AZP54002.1    AY261366    AY261361    AY261363    MH910496    AZP54181.1    KM111295    AJL34238.1    MH025916    MH025917    MH025918    MH025919    MH025920    AXB49288.1    AXB49462.1    AXB49634.1    AXB49805.1    AXB49978.1    KM111294    AJL34073.1    AY261360    KX354450    AOO54392.1    AM712239    CAN10159.1    FN557520    CBH29160.1    AM712240    CAN10407.1    KM262844    KM262845    KM102979    KP055815    AIY22250.1    AIY22409.1    AJZ77081.1    AKO62741.1    U18466    NZXR01000083    MAR56918.1    LT706986    SIP85889.1    DS268443    EFP01534.1    LFJK02001496    POM29413.1    HE600958    CAP31242.1    CZDJ02000003    SMH63297.1    PDUG01000001    PIC51499.1    POM29414.1    BX284601    CCD65150.1    NMWX01000912    OZF74828.1    NIPN01000313    OZF90428.1    NYYR01000118    MAE21843.1    KU702949    KU702951    KU556803    AMN83779.1    AMN84555.1    AMP44302.1    NZZO01000005    MAR49587.1    MN448297    QFG75026.1    LT839607    SME64803.1    KJ614390    KU702948    KU702950    KU702952    AIB51844.1    AMN83077.1    AMN84060.1    AMN85046.1    KT997790    ANS04265.1   
Pfam
PF02732   ERCC4
PF00397   WW
PF17907   AWS
PF00856   SET
Interpro
IPR011335   Restrct_endonuc-II-like
IPR006166   ERCC4_domain
IPR003583   Hlx-hairpin-Hlx_DNA-bd_motif
IPR027421   DNA_pol_lamdba_lyase_dom_sf
IPR003616   Post-SET_dom
IPR001214   SET_dom
IPR036020   WW_dom_sf
IPR001202   WW_dom
IPR006560   AWS_dom
SUPFAM
SSF52980   SSF52980
SSF47802   SSF47802
SSF51045   SSF51045
Gene 3D
PDB
2BGW     E-value=0.000323422,     Score=104

Ontologies

KEGG

Subcellular Location

From MSLVP
Cytoplasm
From Uniprot
Nucleus  

Topology

Length:
168
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.34913
Exp number, first 60 AAs:
0.00366
Total prob of N-in:
0.10065
outside
1  -  168
 
 

Population Genetic Test Statistics

Pi
0.0237901
Theta
0.032996
Tajima's D
-1.2187422
CLR
0.124234
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
AKO62741.1
China_AnhuiXCGQ_2018 Protein
AYW34031.1
China_ASFV-SY18_2018 Protein
AKO62741.1
Poland_Pol16_20186_o7_2016-2017 Protein
AXZ95834.1
Poland_Pol16_20538_o9_2016-2017 Protein
AJL34238.1
Poland_Pol16_20540_o10_2016-2017 Protein
AJL34238.1
Poland_Pol16_29413_o23_2016-2017 Protein
AJL34238.1
Poland_Pol17_03029_C201_2016-2017 Protein
AXZ96022.1
Poland_Pol17_04461_C210_2016-2017 Protein
AXZ96117.1
Poland_Pol17_05838_C220_2016-2017 Protein
AJL34238.1
Poland_ASFV_POL_Podlaskie_2015 Protein
AJL34238.1
Uganda_R8_2015 Protein
AXB49288.1
Uganda_R7_2015 Protein
AXB49462.1
Uganda_R25_2015 Protein
AXB49634.1
Uganda_N10_2015 Protein
AXB49805.1
Uganda_R35_2015 Protein
AXB49978.1
Estonia_2014 Protein
SPS73482.1
Italy_26544_OG10_2010 Protein
AJZ77081.1
Italy_47_Ss_2008_2008 Protein
AOO54392.1
Portugal_OURT_88.3_1988 Protein
CAN10407.1
Spain_E75_1975 Protein
CBH29160.1
Russia_Georgia_2007 Protein
CBW46725.1
Kenya_Tk1_2005    
Kenya_Bus_2006 Protein
Protein
AJL34238.1
AJL34238.1
Russia_Odintsovo_2014 Protein
AJL34238.1
Portugal_L60_1960 Protein
AIY22250.1
Portugal_NHV_1968 Protein
AIY22409.1
Russia_Kashino_2013 Protein
AJL34238.1
Benin_1997 Protein
CAN10159.1
South_Africa_KNP_Pretorisuskop_1996 Protein
AJL34238.1
South_Africa_MGR_Mkuzi_1979 Protein
AJL34238.1
Malawi_Lil_1983 Protein
AJL34238.1
Kenya_1950    
Namibia_Warthog_1980 Protein
AJL34238.1
South_Africa_Warmbaths_1987 Protein
AJL34238.1
Malawi_Tengani_1962 Protein
AJL34238.1
China_HLJ_2018 Protein
QBH90547.1
China_LN_2018 Protein
QBH90732.1
China_wbBS01_2018 Protein
QDL88090.1
Ukraine_Kyiv_2014 Protein
Protein
Protein
QED21623.1
QED21624.1
QED21625.1
Belgium_Etalle_wb_2018 Protein
QED90502.1
Lithuania_LT14_2014 Protein
QEY87865.1
South_Africa_1985 Protein
QGM12913.1
South_Africa_2_2008 Protein
QGM12839.1
Zambia_LIV_1983 Protein
QGM12721.1
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