Strain

Poland_Pol17_04461_C210_2016-2017 (Region: Poland; Strain: Pol17_04461_C210; Date: 2016-2017)

Gene

MGF_110-11L

Description

Annotated in NCBI, MGF_110-11L

Location

MG939588.1(-):12796-13155

GenBank Accession

AXZ96076.1

Full name

Protein MGF 110-11L       + More
Protein LIS 117
Protein MGF 110-13L
Protein MGF 360-3L

CDS

ATGAAACTACTTGCTCTTTTATGTATTTTGATTTGGCTATCTCAGCCGGGTTTAAATCGACCCCTTTCCATCTTTTATATGAAACAAAATTTACCAAGGACTTATACGCCTCCTATAAGAGAGCTTGAATACTGGTGCACGTATGGAAAACACTGTGATTTCTGCTGGGAATGTAGGAACGGTATTTGTAAAAATAAAGTGTGGGATGATATGCCTCTTATTAAACAAAATGATTATATTAGTCAATGTAGTATTGCCCGCTATTTTGACCGTTGTATGTATTTTATTAAACCCAAATCACCGTATATTCATTATATGGATTGTTTTCAGCCTACAGCGTATAAAGGGTTTAGTCATTAA

Protein

MKLLALLCILIWLSQPGLNRPLSIFYMKQNLPRTYTPPIRELEYWCTYGKHCDFCWECRNGICKNKVWDDMPLIKQNDYISQCSIARYFDRCMYFIKPKSPYIHYMDCFQPTAYKGFSH

Function

Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.

Similarity

Belongs to the asfivirus MGF 110 family.
Belongs to the asfaviruses V110 family.

Keywords

Complete proteome Glycoprotein Host membrane Membrane Transmembrane Transmembrane helix Early protein Signal

Feature

chain Protein MGF 110-11L

Uniprot

A0A0C5BC29 P0C9J4 A0A0C5B2D9 A0A2Z5DFP2 P26702 A0A2Z5DET6 + More
P0C9K1 A0A0C5AWJ1 A9JKS3 A0A0A1E020 A0A1C6ZY46 E0WME0 A0A385KLX5 A0A3G1EUS1 A0A0C5B216 A0A3G1EUS4 P0C9J5

Pubmed

25645905 2219721 18198370 25406173 21470447

EMBL

KM111294 AJL34023.1 AY261360 KM111295 AJL34186.1 MH025918 + More
AXB49583.1 M58155 MH025916 MH025917 MH025919 MH025920 AXB49239.1 AXB49413.1 AXB49585.1 AXB49758.1 AXB49929.1 AY261361 AJL34189.1 AM712239 CAN10107.1 KM262844 AIY22199.1 KM102979 AJZ77135.1 FR682468 CBW46668.1 MG939583 AXZ95787.1 KX354450 AOO54322.1 AJL34026.1 AOO54321.1

Proteomes

UP000105860 UP000000861 UP000101566 UP000000860 UP000130745 UP000142390 + More
UP000117635 UP000141072 UP000266411

Pfam

PF01639 v110

Interpro

IPR004848 V110_vir

ProteinModelPortal

A0A0C5BC29 P0C9J4 A0A0C5B2D9 A0A2Z5DFP2 P26702 A0A2Z5DET6 + More
P0C9K1 A0A0C5AWJ1 A9JKS3 A0A0A1E020 A0A1C6ZY46 E0WME0 A0A385KLX5 A0A3G1EUS1 A0A0C5B216 A0A3G1EUS4 P0C9J5

PDB

4ZJC E-value=0.041904, Score=84

Ontologies

GO

GO:0016021 C:integral component of membrane
GO:0033644 C:host cell membrane

Subcellular Location

From MSLVP

Multi-Pass Membrane

From Uniprot

Host membrane

Topology

Length:

119

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.42419

Exp number, first 60 AAs:

0.42394

Total prob of N-in:

0.04020

outside

1 - 119

Population Genetic Test Statistics

Pi

0.1268527

Theta

0.2341029

Tajima's D

-1.5757755

CLR

0.283927

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971
China_AnhuiXCGQ_2018	Protein Protein Protein	AYW33965.1 AYW33966.1 AYW33967.1
China_ASFV-SY18_2018	Protein Protein Protein Genetic Remain	CBW46664.1 CBH29107.1 CAN10108.1 CBW46668.1
Poland_Pol16_20186_o7_2016-2017	Protein Protein Protein	AXZ95784.1 AXZ95785.1 AXZ95787.1
Poland_Pol16_20538_o9_2016-2017	Protein Protein Protein	AXZ95937.1 AXZ95938.1 AXZ95940.1
Poland_Pol16_20540_o10_2016-2017	Protein	AIY22367.1
Poland_Pol16_29413_o23_2016-2017	Protein Protein	AIY22367.1 AXZ95964.1
Poland_Pol17_03029_C201_2016-2017	Protein Protein	AIY22367.1 AXZ95981.1
Poland_Pol17_04461_C210_2016-2017	Protein Protein	AIY22367.1 AXZ96076.1
Poland_Pol17_05838_C220_2016-2017	Protein	AIY22367.1
Poland_ASFV_POL_Podlaskie_2015	Protein	AIY22367.1
Uganda_R8_2015	Protein Protein Protein Protein	AIY22367.1 AXB49236.1 AXB49237.1 AXB49240.1
Uganda_R7_2015	Protein Protein Protein Protein	AIY22367.1 AXB49410.1 AXB49411.1 AXB49414.1
Uganda_R25_2015	Protein Protein	AXB49583.1 AXB49586.1
Uganda_N10_2015	Protein Protein Protein Protein	AIY22367.1 AXB49755.1 AXB49756.1 AXB49759.1
Uganda_R35_2015	Protein Protein Protein Protein	AIY22367.1 AXB49926.1 AXB49927.1 AXB49930.1
Estonia_2014	Protein	SPS73426.1
Italy_26544_OG10_2010	Protein Protein Protein	AIY22367.1 AJZ77108.1 AJZ77154.1
Italy_47_Ss_2008_2008	Protein Protein Protein	AOO54318.1 AOO54319.1 AOO54323.1
Portugal_OURT_88.3_1988	Protein Protein	CAN10364.1 CAN10365.1
Spain_E75_1975	Protein Protein Protein	CBH29106.1 CBH29107.1 CBH29109.1
Russia_Georgia_2007	Protein Protein Protein	CBW46664.1 CBW46665.1 CBW46668.1
Kenya_Tk1_2005	Protein Protein Protein	AJL34023.1 AJL34024.1 AJL34026.1
Kenya_Bus_2006	Protein Protein Protein	AJL34186.1 AJL34187.1 AJL34190.1
Russia_Odintsovo_2014	Protein	AIY22367.1
Portugal_L60_1960	Protein Protein Protein	AIY22196.1 AIY22197.1 AIY22200.1
Portugal_NHV_1968	Protein Protein Protein	AIY22367.1 AIY22366.1 AIY22367.1
Russia_Kashino_2013	Protein	AIY22367.1
Benin_1997	Protein Protein	CAN10105.1 CAN10108.1
South_Africa_KNP_Pretorisuskop_1996
South_Africa_MGR_Mkuzi_1979	Protein	AIY22367.1
Malawi_Lil_1983	Protein	AIY22367.1
Kenya_1950	Protein	AIY22367.1
Namibia_Warthog_1980	Protein	AIY22367.1
South_Africa_Warmbaths_1987	Protein	AIY22367.1
Malawi_Tengani_1962
China_HLJ_2018	Protein Protein Protein	QBH90487.1 QBH90488.1 QBH90491.1
China_LN_2018	Protein Protein Protein	QBH90672.1 QBH90673.1 QBH90676.1
China_wbBS01_2018	Protein Protein Protein	QDL88029.1 QDL88030.1 QDL88033.1
Ukraine_Kyiv_2014	Protein Protein Protein	QED21556.1 QED21557.1 QED21559.1
Belgium_Etalle_wb_2018	Protein Protein	AIY22367.1 QED90444.1
Lithuania_LT14_2014	Protein Protein Protein	QEY87803.1 QEY87804.1 QEY87808.1
South_Africa_1985
South_Africa_2_2008	Protein	AJZ77135.1
Zambia_LIV_1983

Sequence