Strain

Poland_Pol16_20538_o9_2016-2017 (Region: Poland;  Strain: Pol16_20538_o9;  Date: 2016-2017)

Gene

MGF 110-4L

Description

Annoated by sequence mapping,  Member of multigene family 110 (XP124L)

Location

MG939584.1(-):7283-7657

GenBank Accession

CAN10358.1

Full name

Protein LIS 124-1       + More
Protein MGF 110-4L      
Protein LIS 124-2      
Protein MGF 110-3L      
Protein MGF 110-6L      
Protein V118      
Protein MGF 110-5L      
Protein LIS 121-1      
Protein LIS 137      
Protein MGF 110-7L      
Protein LIS 117      
Protein MGF 110-13L      
Protein MGF 110-9L      
Protein MGF 110-11L      
Protein MGF 360-1L      
Protein MGF 110-1L      
Protein LIS 119-1      
Protein LIS 290      

CDS

ATGTTGGTGATCTTCTTGGAAATTCTTGGCCTGCTGGCCAATCAGGTCTTAGGACTACCTACTCAGGCAGGAGGGCATCTTCGTTCAACGGATAATCCTCCACAAGAAGAACTTGGATACTGGTGTACTTACATGGAAAACTGCAAGTTTTGCTGGGAATGTGCACATGGAATTTGCAAGAACAAGGTGAATAAGAGCATGCCATTGATTGTTGAGAACAGTTATTTGACATCTTGTGAGGTTTCTCGCTGGTATAACCAGTGTACATATGGTGAAGGAAATGGACATTACCATGTTATGGATTGTTCTGATCCAGTACCTCACAACCGCCCCCACCAATTGTTAATGAAAATTTATGAAAAGGATGATCTGTAA

Protein

MLVIFLEILGLLANQVLGLPTQAGGHLRSTDNPPQEELGYWCTYMENCKFCWECAHGICKNKVNKSMPLIVENSYLTSCEVSRWYNQCTYGEGNGHYHVMDCSDPVPHNRPHQLLMKIYEKDDL

Function

Causes the redistribution of lumenal ER protein to an enlarged ERGIC compartment.
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.

Similarity

Belongs to the asfaviruses V110 family.
Belongs to the asfivirus MGF 110 family.

Keywords

Early protein   Signal   Complete proteome   Glycoprotein   Reference proteome   Virion   Host membrane   Membrane   Transmembrane   Transmembrane helix   Host endoplasmic reticulum   Repeat  

Feature

chain  Protein LIS 124-1

Uniprot

A9JLI5   Q76S48   P26707   A0A0N7CSV4   P18558   P0C9H3   + More
A0A0C5AZ97   P26708   P0C9H0   A9JLI7   A0A0A1E3D3   E0WMC5   A0A385KME3   E0WMC7   A0A385KMB9   P0C9H1   P0C9H2   A0A0C5AZR5   P0C9G9   A0A0C5AWI3   A0A0C5AW76   A0A0C5B207   A0A0C5B2D4   P0C9H8   A0A0C5AYT3   P0C9H7   P0C9I0   A0A0N7CQU7   P68745   P68744   A0A0C5AZ52   P0C9H9   A0A0N7CQU8   P18557   P26705   P0C9H4   P0C9H6   A0A2Z5DF98   P0C9H5   P26709   P0C9I4   P0C9I2   P0C9I1   A0A0C5BC26   E0WMC9   A0A385KMG5   P0C9I3   A0A2Z5DG86   P26702   A0A3G1EUS1   A0A0C5AZS1   A0A0C5AYT5   A0A2Z5DGN8   A0A0C5B2D9   A0A0C5BC29   P0C9K1   A9JKS3   A0A0A1E020   A0A3G1EUS4   P0C9J0   E0WMD4   A0A385KMQ4   A0A1C6ZY46   P0C9J3   A0A385KMA0   A0A2Z5DFP2   A0A2Z5DET6   E0WME0   A0A385KLX5   P0C9J6   A0A0C5AWJ1   P0C9J4   A0A0C5B216   A0A0A1DXS7   P18560   A9JKR7   D4I5J2   A0A0A1E0W7   A0A0N7CUL1   A0A0C5AYS9   P0C9I9   P26703   P26710   A9JLI2   A0A2Z5DG74   A0A2Z5DF99   A0A0C5AZ45   E0WMD6   A0A385KMG0  

Pubmed

18198370    9482593    25406173    2219721    26618713    2325202    + More
11831707    9499098    15016891    25645905    21470447   

EMBL

AM712240    CAN10358.1    U81365    KM262845    AAC40560.1    AIY22360.1    + More
M58155    KP055815    AKO62692.1    M36467    U18466    AY261363    KM111294    AJL34015.1    AY261366    CAN10359.1    AIY22361.1    FR682468    CBW46653.1    MG939583    MG939586    MG939587    MG939588    AXZ95776.1    AXZ95956.1    AXZ95973.1    AXZ96068.1    CBW46655.1    AXZ95777.1    AXZ95957.1    AXZ95974.1    AXZ96069.1    AY261360    AY261361    KM111295    MH025916    MH025917    MH025918    MH025919    MH025920    AJL34180.1    AXB49229.1    AXB49402.1    AXB49576.1    AXB49748.1    AXB49919.1    AJL34179.1    AXB49228.1    AXB49401.1    AXB49575.1    AXB49747.1    AXB49918.1    AJL34014.1    AJL34016.1    AJL34181.1    AXB49230.1    AXB49403.1    AXB49577.1    AXB49749.1    AXB49920.1    AJL34017.1    AKO62694.1    AJL34182.1    AXB49231.1    AXB49404.1    AXB49578.1    AXB49750.1    AXB49921.1    AKO62693.1    AXB49232.1    AXB49405.1    AXB49579.1    AXB49751.1    AXB49922.1    AJL34018.1    CBW46657.1    AXZ95779.1    AXZ95959.1    AXZ95976.1    AXZ96071.1    AXB49236.1    AXB49410.1    AXB49755.1    AXB49926.1    KX354450    AOO54322.1    AJL34185.1    AJL34022.1    AXB49235.1    AXB49409.1    AXB49582.1    AXB49754.1    AXB49925.1    AJL34186.1    AJL34023.1    AM712239    CAN10107.1    KM262844    AIY22199.1    AOO54321.1    CBW46662.1    AXZ95782.1    AXZ95962.1    AXZ95979.1    AXZ96074.1    KM102979    AJZ77135.1    MG939584    AXZ95940.1    AXB49583.1    AXB49239.1    AXB49413.1    AXB49585.1    AXB49758.1    AXB49929.1    CBW46668.1    AXZ95787.1    AJL34189.1    AJL34026.1    AIY22195.1    CAN10104.1    FN557520    CBH29105.1    AIY22358.1    AJZ77110.1    AKO62690.1    AOO54316.1    AJL34012.1    CAN10356.1    AXB49745.1    AXB49226.1    AXB49399.1    AXB49573.1    AXB49916.1    AJL34177.1    CBW46664.1    AXZ95784.1    AXZ95937.1    AXZ95964.1    AXZ95981.1    AXZ96076.1   

Proteomes

UP000108903    UP000110401    UP000241813    UP000000624    UP000000859    UP000105860    + More
UP000000858    UP000141072    UP000000861    UP000000860    UP000101566    UP000266411    UP000130745    UP000142390    UP000117635    UP000101090   

PRIDE

P0C9G9    P0C9I9    P26710   

Pfam

PF01639   v110

Interpro

IPR004848   V110_vir

ProteinModelPortal

A9JLI5   Q76S48   P26707   A0A0N7CSV4   P18558   P0C9H3   + More
A0A0C5AZ97   P26708   P0C9H0   A9JLI7   A0A0A1E3D3   E0WMC5   A0A385KME3   E0WMC7   A0A385KMB9   P0C9H1   P0C9H2   A0A0C5AZR5   P0C9G9   A0A0C5AWI3   A0A0C5AW76   A0A0C5B207   A0A0C5B2D4   P0C9H8   A0A0C5AYT3   P0C9H7   P0C9I0   A0A0N7CQU7   P68745   P68744   A0A0C5AZ52   P0C9H9   A0A0N7CQU8   P18557   P26705   P0C9H4   P0C9H6   A0A2Z5DF98   P0C9H5   P26709   P0C9I4   P0C9I2   P0C9I1   A0A0C5BC26   E0WMC9   A0A385KMG5   P0C9I3   A0A2Z5DG86   P26702   A0A3G1EUS1   A0A0C5AZS1   A0A0C5AYT5   A0A2Z5DGN8   A0A0C5B2D9   A0A0C5BC29   P0C9K1   A9JKS3   A0A0A1E020   A0A3G1EUS4   P0C9J0   E0WMD4   A0A385KMQ4   A0A1C6ZY46   P0C9J3   A0A385KMA0   A0A2Z5DFP2   A0A2Z5DET6   E0WME0   A0A385KLX5   P0C9J6   A0A0C5AWJ1   P0C9J4   A0A0C5B216   A0A0A1DXS7   P18560   A9JKR7   D4I5J2   A0A0A1E0W7   A0A0N7CUL1   A0A0C5AYS9   P0C9I9   P26703   P26710   A9JLI2   A0A2Z5DG74   A0A2Z5DF99   A0A0C5AZ45   E0WMD6   A0A385KMG0  

KEGG

vg:22220399     vg:22220401     vg:22220400     vg:22220397    

GO

GO:0044172  C:host cell endoplasmic reticulum-Golgi intermediate compartment
GO:0019012  C:virion
GO:0033644  C:host cell membrane
GO:0016021  C:integral component of membrane
GO:0044166  C:host cell endoplasmic reticulum lumen

From MSLVP

Single-Pass Membrane

From Uniprot

Virion  
Host endoplasmic reticulum-Golgi intermediate compartment  
Host membrane  
Host endoplasmic reticulum lumen  
Membrane  

Length:

124

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.208

Exp number, first 60 AAs:

0.208

Total prob of N-in:

0.02357

outside

1  -  124

 

 

Pi

0.1465306

Theta

0.2105579

Tajima's D

-1.2176129

CLR

1.054035

Interpretation

No evidence of Selection