ASFVdb The African Swine Fever Virus Database
Strain
Italy_47_Ss_2008_2008 (Region: Sardinia, Italy;  Strain: 47/Ss/2008;  Date: 2008)
Gene
pMGF 110-14L
Description
Annotated in NCBI,  Member of multigene family 110 (Lis 121_2)
GenBank Accession
Full name
Protein LIS 121-2       + More
Protein MGF 110-11L      
Protein MGF 360-3L      
Protein LIS 119-2      
 

Sequence

CDS
ATGAAGGTTCTTCTGGGACTTTTGTTGGGCCACTCAGTCCTCATTCTCGCACATGAATTACCAGACTTACCAAGAACCCAGCATCCTCCCAAGAGTGAGCTTTCATATTGGTGTACGTATGTACCACAATGCGACTTCTGTTGGGACTGTCAAGATGGCATTTGCAAAAATAAGATAACGGAATCTCGTTTCATTGACTCCAATCATTCTATTGTAAACTGTAGAGTTTTTCGTGATTCCAAGACTCAATCCTGTTTATATGAAATTTCATATAAAATGCCTAATCACTTTAGCATGGAATGTTTACATCCTAGATCCTATACAGGAAATGAAATATTCATGCAAACATGGGGGGGGGGTGACCAATCAACAATTATCTATAAAGCAATACTGTCTCTATTTCATCATTGGTATTGCTTATACAGGCTGCTTTGTATGTGCGCTTTGTAA
Protein
MKVLLGLLLGHSVLILAHELPDLPRTQHPPKSELSYWCTYVPQCDFCWDCQDGICKNKITESRFIDSNHSIVNCRVFRDSKTQSCLYEISYKMPNHFSMECLHPRSYTGNEIFMQTWGGGDQSTIIYKAILSLFHHWYCLYRLLCMCAL

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Similarity
Belongs to the asfaviruses V110 family.
Belongs to the asfivirus MGF 110 family.
Keywords
Early protein   Signal   Complete proteome   Glycoprotein   Host membrane   Membrane   Transmembrane   Transmembrane helix  
Feature
chain  Protein LIS 121-2
Pfam
PF01639   v110
Interpro
IPR004848   V110_vir
PDB
4ZJC     E-value=0.041904,     Score=84

Ontologies

Subcellular Location

From MSLVP
Multi-Pass Membrane
From Uniprot
Host membrane  

Topology

Length:
149
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.87104
Exp number, first 60 AAs:
0.0319
Total prob of N-in:
0.01123
outside
1  -  149
 
 

Population Genetic Test Statistics

Pi
0.076124
Theta
0.1888576
Tajima's D
-2.1970833
CLR
328.649539
Interpretation
Possibly Positive selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971    
China_AnhuiXCGQ_2018 Protein
Protein
Protein
AYW33965.1
AYW33966.1
AYW33967.1
China_ASFV-SY18_2018 Protein
Protein
Protein
Genetic Remain
CBW46664.1
CBH29107.1
CAN10108.1
CBW46668.1
Poland_Pol16_20186_o7_2016-2017 Protein
Protein
Protein
AXZ95784.1
AXZ95785.1
AXZ95787.1
Poland_Pol16_20538_o9_2016-2017 Protein
Protein
Protein
AXZ95937.1
AXZ95938.1
AXZ95940.1
Poland_Pol16_20540_o10_2016-2017 Protein
AIY22367.1
Poland_Pol16_29413_o23_2016-2017 Protein
Protein
AIY22367.1
AXZ95964.1
Poland_Pol17_03029_C201_2016-2017 Protein
Protein
AIY22367.1
AXZ95981.1
Poland_Pol17_04461_C210_2016-2017 Protein
Protein
AIY22367.1
AXZ96076.1
Poland_Pol17_05838_C220_2016-2017 Protein
AIY22367.1
Poland_ASFV_POL_Podlaskie_2015 Protein
AIY22367.1
Uganda_R8_2015 Protein
Protein
Protein
Protein
AIY22367.1
AXB49236.1
AXB49237.1
AXB49240.1
Uganda_R7_2015 Protein
Protein
Protein
Protein
AIY22367.1
AXB49410.1
AXB49411.1
AXB49414.1
Uganda_R25_2015 Protein
Protein
AXB49583.1
AXB49586.1
Uganda_N10_2015 Protein
Protein
Protein
Protein
AIY22367.1
AXB49755.1
AXB49756.1
AXB49759.1
Uganda_R35_2015 Protein
Protein
Protein
Protein
AIY22367.1
AXB49926.1
AXB49927.1
AXB49930.1
Estonia_2014 Protein
SPS73426.1
Italy_26544_OG10_2010 Protein
Protein
Protein
AIY22367.1
AJZ77108.1
AJZ77154.1
Italy_47_Ss_2008_2008 Protein
Protein
Protein
AOO54318.1
AOO54319.1
AOO54323.1
Portugal_OURT_88.3_1988 Protein
Protein
CAN10364.1
CAN10365.1
Spain_E75_1975 Protein
Protein
Protein
CBH29106.1
CBH29107.1
CBH29109.1
Russia_Georgia_2007 Protein
Protein
Protein
CBW46664.1
CBW46665.1
CBW46668.1
Kenya_Tk1_2005 Protein
Protein
Protein
AJL34023.1
AJL34024.1
AJL34026.1
Kenya_Bus_2006 Protein
Protein
Protein
AJL34186.1
AJL34187.1
AJL34190.1
Russia_Odintsovo_2014 Protein
AIY22367.1
Portugal_L60_1960 Protein
Protein
Protein
AIY22196.1
AIY22197.1
AIY22200.1
Portugal_NHV_1968 Protein
Protein
Protein
AIY22367.1
AIY22366.1
AIY22367.1
Russia_Kashino_2013 Protein
AIY22367.1
Benin_1997 Protein
Protein
CAN10105.1
CAN10108.1
South_Africa_KNP_Pretorisuskop_1996    
South_Africa_MGR_Mkuzi_1979 Protein
AIY22367.1
Malawi_Lil_1983 Protein
AIY22367.1
Kenya_1950 Protein
AIY22367.1
Namibia_Warthog_1980 Protein
AIY22367.1
South_Africa_Warmbaths_1987 Protein
AIY22367.1
Malawi_Tengani_1962    
China_HLJ_2018 Protein
Protein
Protein
QBH90487.1
QBH90488.1
QBH90491.1
China_LN_2018 Protein
Protein
Protein
QBH90672.1
QBH90673.1
QBH90676.1
China_wbBS01_2018 Protein
Protein
Protein
QDL88029.1
QDL88030.1
QDL88033.1
Ukraine_Kyiv_2014 Protein
Protein
Protein
QED21556.1
QED21557.1
QED21559.1
Belgium_Etalle_wb_2018 Protein
Protein
AIY22367.1
QED90444.1
Lithuania_LT14_2014 Protein
Protein
Protein
QEY87803.1
QEY87804.1
QEY87808.1
South_Africa_1985    
South_Africa_2_2008 Protein
AJZ77135.1
Zambia_LIV_1983    
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