Strain

Portugal_NHV_1968 (Region: Portugal; Strain: NHV; Date: 1968)

Gene

pMGF 110-5L

Description

Annotated in NCBI, member of multigene family 110 (V82L)

Location

KM262845.1(-):7773-8147

GenBank Accession

AIY22361.1

Full name

Protein MGF 360-1L

Sequence

CDS

ATGCTGGTGATTATTCTGGGAGTTATTGGCCTGCTGGCCAATCAGGTCTTAGGACTACCTACTCAGGCAGGAGGGCATCTTCGTTCAACGGATAATCCTCCACAAGAAGAACTTGGATACTGGTGTACTTACATGGAAAGCTGCAAGTTTTGCTGGGAATGTGCACATGGAATTTGCAAGAACAAGGTGAATGAGAGCATGCCATTGATTATTGAGAACAGTTATTTGACATCTTGTGAGGTTTCTCGCTGGTATAACCAGTGCACATATAGTGAAGGAAATGGGCATTACCATGTTATGGATTGTTCTGATCCAGTACCTCACAATCGTCCACACCGATTGTTAATGAAAATTTATGAAAAGGAAGATCTGTGA

Protein

MLVIILGVIGLLANQVLGLPTQAGGHLRSTDNPPQEELGYWCTYMESCKFCWECAHGICKNKVNESMPLIIENSYLTSCEVSRWYNQCTYSEGNGHYHVMDCSDPVPHNRPHRLLMKIYEKEDL

Summary

Function

Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.

Similarity

Belongs to the asfivirus MGF 110 family.

Keywords

Complete proteome Glycoprotein Host membrane Membrane Transmembrane Transmembrane helix

Feature

chain Protein MGF 360-1L

Uniprot

P0C9J6

EMBL

AY261363

Proteomes

UP000000859

Pfam

PF01639 v110

Interpro

IPR004848 V110_vir

ProteinModelPortal

P0C9J6

Ontologies

GO:0016021 C:integral component of membrane
GO:0033644 C:host cell membrane

Subcellular Location

From MSLVP

Single-Pass Membrane

From Uniprot

Host membrane

Topology

Length:

124

Number of predicted TMHs:

Exp number of AAs in TMHs:

4.36244

Exp number, first 60 AAs:

4.36225

Total prob of N-in:

0.22869

outside

1 - 124

Population Genetic Test Statistics

0.1912542

Theta

0.2065142

Tajima's D

-0.3584346

CLR

0.930058

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971	Protein	AKO62692.1
China_AnhuiXCGQ_2018	Protein Protein	AYW33962.1 AYW33963.1
China_ASFV-SY18_2018	Protein Protein	AKO62692.1 CBW46655.1
Poland_Pol16_20186_o7_2016-2017	Protein Protein	AXZ95776.1 AXZ95777.1
Poland_Pol16_20538_o9_2016-2017	Protein	CAN10358.1
Poland_Pol16_20540_o10_2016-2017	Protein	CAN10358.1
Poland_Pol16_29413_o23_2016-2017	Protein Protein	AXZ95956.1 AXZ95957.1
Poland_Pol17_03029_C201_2016-2017	Protein Protein	AXZ95973.1 AXZ95974.1
Poland_Pol17_04461_C210_2016-2017	Protein Protein	AXZ96068.1 AXZ96069.1
Poland_Pol17_05838_C220_2016-2017	Protein	CAN10358.1
Poland_ASFV_POL_Podlaskie_2015	Protein	CAN10358.1
Uganda_R8_2015	Protein Protein	AXB49228.1 AXB49229.1
Uganda_R7_2015	Protein Protein	AXB49401.1 AXB49402.1
Uganda_R25_2015	Protein Protein	AXB49575.1 AXB49576.1
Uganda_N10_2015	Protein Protein	AXB49747.1 AXB49748.1
Uganda_R35_2015	Protein Protein	AXB49918.1 AXB49919.1
Estonia_2014
Italy_26544_OG10_2010
Italy_47_Ss_2008_2008
Portugal_OURT_88.3_1988	Protein Protein Protein	CAN10358.1 CAN10358.1 CAN10359.1
Spain_E75_1975
Russia_Georgia_2007	Protein Protein	CBW46653.1 CBW46655.1
Kenya_Tk1_2005	Protein Protein	AJL34014.1 AJL34015.1
Kenya_Bus_2006	Protein Protein	AJL34179.1 AJL34180.1
Russia_Odintsovo_2014	Protein	CAN10358.1
Portugal_L60_1960
Portugal_NHV_1968	Protein Protein	AIY22360.1 AIY22361.1
Russia_Kashino_2013	Protein	CAN10358.1
Benin_1997
South_Africa_KNP_Pretorisuskop_1996
South_Africa_MGR_Mkuzi_1979	Protein	CAN10358.1
Malawi_Lil_1983	Protein	CAN10358.1
Kenya_1950	Protein	CAN10358.1
Namibia_Warthog_1980	Protein	CAN10358.1
South_Africa_Warmbaths_1987	Protein	CAN10358.1
Malawi_Tengani_1962	Protein	CAN10358.1
China_HLJ_2018	Protein Protein	QBH90476.1 QBH90478.1
China_LN_2018	Protein Protein	QBH90661.1 QBH90663.1
China_wbBS01_2018	Protein Protein	QDL88019.1 QDL88021.1
Ukraine_Kyiv_2014	Protein Protein	QED21548.1 QED21549.1
Belgium_Etalle_wb_2018	Protein Protein	QED90433.1 QED90435.1
Lithuania_LT14_2014	Protein Protein	QEY87792.1 QEY87794.1
South_Africa_1985	Protein	CAN10358.1
South_Africa_2_2008	Protein	CAN10358.1
Zambia_LIV_1983	Protein	CAN10358.1