ASFVdb The African Swine Fever Virus Database
Strain
Russia_Georgia_2007 (Region: Russia;  Strain: Georgia 2007/1;  Date: 2007)
Gene
MGF_110-5L-6L
Description
Annotated in NCBI,  fussion of two MGF_110
GenBank Accession
Full name
Protein MGF 110-6L       + More
Protein V118      
Protein MGF 110-5L      
Protein LIS 121-1      
Protein LIS 124-1      
Protein MGF 110-4L      
Protein LIS 124-2      
Protein MGF 110-3L      
Protein MGF 110-7L      
Protein LIS 137      
Protein MGF 110-14L      
Protein LIS 117      
 

Sequence

CDS
ATGTTGGTGATCTTCTTGGGAATTCTTGGCCTTCTGGCCAGCCAGGTTTCAAGTCAGCTCGTTGGACAACTTCGTCCAACAGAGGAGCCTCCAGAGGAAGAACTCGAATACTGGTGTGCCTACATGGAAAGTTGCCAATTTTGCTGGGACTGCCAAGACGGCACTTGTATAAACAAAATAGATGGGTCAGTAATTTACAAGAATGAGTATGTGAAATCATGTCTGGTTTCCCGTTGGCTGGATAAATGTATGTATGATTTAGATAAGGGTATCTACCATACCATGAATTGCAACCAGGTCTTAGGGCTACCTAATCAACCAGCTGGACAACTTCATCCAACGGATAATCCTCCACAAGAAGAACTTGAATACTGGTGCACTTATACAGAAAACTGCAAGTTTTGCTGGAATTGTCAAAATGGCCTTTGTGAGGGCAAATTGGAGAATACAACAATTCTTGAAAATGAGTATGTGCAATCATGTATAGTTTCCCGCTGGCTAAATAAATGTATGTATGATCTAGGACAGGGGATTCACCATGTAATGGCCTGTTCTGAACCAAAGCCCTGGAATCCTTACAAAATCTTAAAGAGAGAGTGGAAAGAAAATAATAGTTAA
Protein
MLVIFLGILGLLASQVSSQLVGQLRPTEEPPEEELEYWCAYMESCQFCWDCQDGTCINKIDGSVIYKNEYVKSCLVSRWLDKCMYDLDKGIYHTMNCNQVLGLPNQPAGQLHPTDNPPQEELEYWCTYTENCKFCWNCQNGLCEGKLENTTILENEYVQSCIVSRWLNKCMYDLGQGIHHVMACSEPKPWNPYKILKREWKENNS

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Causes the redistribution of lumenal ER protein to an enlarged ERGIC compartment.
Similarity
Belongs to the asfivirus MGF 110 family.
Belongs to the asfaviruses V110 family.
Keywords
Complete proteome   Early protein   Glycoprotein   Host endoplasmic reticulum   Signal   Reference proteome   Virion   Host membrane   Membrane   Transmembrane   Transmembrane helix  
Feature
chain  Protein MGF 110-6L
Pfam
PF01639   v110
Interpro
IPR004848   V110_vir
PDB
6NU2     E-value=3.33979,     Score=66

Ontologies

Subcellular Location

From MSLVP
Host nucleus. Host cytoplasm.
From Uniprot
Host endoplasmic reticulum lumen  
Virion  
Host endoplasmic reticulum-Golgi intermediate compartment  
Host membrane  
Host endoplasmic reticulum lumen  
Virion  
Host endoplasmic reticulum-Golgi intermediate compartment  
Host membrane  

Topology

Length:
205
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.1987
Exp number, first 60 AAs:
0.1987
Total prob of N-in:
0.01415
Length:
205
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.1987
Exp number, first 60 AAs:
0.1987
Total prob of N-in:
0.01415
outside
1  -  205
outside
1  -  205
 
 

Population Genetic Test Statistics

Pi
0.20881
Theta
0.2626585
Tajima's D
-0.8682195
CLR
1.486478
Interpretation
No evidence of Selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971 Protein
Protein
AKO62693.1
AKO62694.1
China_AnhuiXCGQ_2018 Protein
AYW33959.1
China_ASFV-SY18_2018 Protein
Genetic Remain
AJL34181.1
AKO62694.1
Poland_Pol16_20186_o7_2016-2017 Protein
AXZ95778.1
Poland_Pol16_20538_o9_2016-2017 Protein
CBW46656.1
Poland_Pol16_20540_o10_2016-2017 Protein
CBW46656.1
Poland_Pol16_29413_o23_2016-2017 Protein
AXZ95958.1
Poland_Pol17_03029_C201_2016-2017 Protein
AXZ95975.1
Poland_Pol17_04461_C210_2016-2017 Protein
AXZ96070.1
Poland_Pol17_05838_C220_2016-2017 Protein
CBW46656.1
Poland_ASFV_POL_Podlaskie_2015 Protein
CBW46656.1
Uganda_R8_2015 Protein
Protein
AXB49230.1
AXB49231.1
Uganda_R7_2015 Protein
Protein
AXB49403.1
AXB49404.1
Uganda_R25_2015 Protein
Protein
AXB49577.1
AXB49578.1
Uganda_N10_2015 Protein
Protein
AXB49749.1
AXB49750.1
Uganda_R35_2015 Protein
Protein
AXB49920.1
AXB49921.1
Estonia_2014    
Italy_26544_OG10_2010    
Italy_47_Ss_2008_2008    
Portugal_OURT_88.3_1988    
Spain_E75_1975    
Russia_Georgia_2007 Protein
Protein
CBW46656.1
CBW46656.1
Kenya_Tk1_2005 Protein
Protein
AJL34016.1
AJL34017.1
Kenya_Bus_2006 Protein
Protein
AJL34181.1
AJL34182.1
Russia_Odintsovo_2014 Protein
CBW46656.1
Portugal_L60_1960    
Portugal_NHV_1968    
Russia_Kashino_2013 Protein
CBW46656.1
Benin_1997    
South_Africa_KNP_Pretorisuskop_1996    
South_Africa_MGR_Mkuzi_1979    
Malawi_Lil_1983    
Kenya_1950    
Namibia_Warthog_1980    
South_Africa_Warmbaths_1987    
Malawi_Tengani_1962    
China_HLJ_2018 Protein
QBH90479.1
China_LN_2018 Protein
QBH90664.1
China_wbBS01_2018 Protein
QDL88022.1
Ukraine_Kyiv_2014 Protein
QED21550.1
Belgium_Etalle_wb_2018 Protein
QED90436.1
Lithuania_LT14_2014 Protein
QEY87795.1
South_Africa_1985    
South_Africa_2_2008    
Zambia_LIV_1983    
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