ASFVdb The African Swine Fever Virus Database
Strain
South_Africa_KNP_Pretorisuskop_1996 (Region: South Africa, Kruger National Park;  Strain: Pretorisuskop/96/4;  Date: 1996)
Gene
MGF_360-4L
Description
With frameshift mutation but translatable,  MGF_360-4L
GenBank Accession
 

Sequence

CDS
ATGAACTCTTTACAGGTTCTTACAAAAAAAGTCTTGATAGAAACCAAGGCTTTTTCAAATTATCATGAGGATGATATTTACATTCTACAACAGCTTGGACTATGGTGGGAAATCGGACCCATAGGTTTTTGTAAGCAATGTAAAATGGTAACCGGTGGCTCTATGTCATGCTCTGATGTCGACAGTTATGAGCTTGACAGAGCCTTAGTAAAAGCTGTGAAGGAAAACCAGACTGATCTAATTAAGTTATTTGTTTTATGGGGTGCCGAAATTAATTTTGGCATCATGTGTGCCAAAACGAAGCAGACTAAAGACCTGTGTATCCAACTAGGAGCCGATCCACAATTTTTAGATGTAGGGTTGTATAATATGTTTGTTTATCTTGTCAAACGAAAAAAGGTTTTACTGGCGATTGAAATTTATTATGACAATATTTTGATTCTCGATAGCTTTGATAGCTATGATTTTCACCTATTGATAGACTTTATGTACAATCGTTTTATCCTATATTTAGATGAAAAAGACGAAGAAATGACGAGAAATGCACTTGTATTAAAATTTTGGTATAAGTTCGCCATAGATTTTAAACTTGTAAAACCTATTCGTTATCTTAGTAAAAAATTTCCCCATTTAGATATTTGGCGCTTAAAAGCGGCTATATACTTAGGTAATATTGATGAAGTTCATCGTGCGTATTTTCAGGAAAATATACGTTTAGATCCAAATGACATGATGTTACTTGCCTGCATGTATCCCCAGAATAAATTAGGTATATATTATTGTTTTGCTTTAGGCGCAGATATAGACAATGCTTTAGATATATTGCTACGTTTTGATGAAACAAATAAGCAAATACATAGGGAAACCAGAGGGGAAATCATTTTTAATATAGAACGTGGTTATTTGATTAATATATATTTTTGTATAAGTTTGGGTGCCAATCCTTATATAAAAAAGATACAAGATACTATTAAACAAAAACATAGCAATATTATGATTCTACTTTTTTCTAAGAAAAAACTATTAAGCCCACATTCAGTTCTTCAAAATAAAATATTAGATCCTAGTGATGTGTATAAAATGATTTCAACCTATGAAAATACAGAAAGTTTTTATCCATTTTCTTCGCTAGCAGTTAAGTTGATACAACAAGCAAAA
Protein
MNSLQVLTKKVLIETKAFSNYHEDDIYILQQLGLWWEIGPIGFCKQCKMVTGGSMSCSDVDSYELDRALVKAVKENQTDLIKLFVLWGAEINFGIMCAKTKQTKDLCIQLGADPQFLDVGLYNMFVYLVKRKKVLLAIEIYYDNILILDSFDSYDFHLLIDFMYNRFILYLDEKDEEMTRNALVLKFWYKFAIDFKLVKPIRYLSKKFPHLDIWRLKAAIYLGNIDEVHRAYFQENIRLDPNDMMLLACMYPQNKLGIYYCFALGADIDNALDILLRFDETNKQIHRETRGEIIFNIERGYLINIYFCISLGANPYIKKIQDTIKQKHSNIMILLFSKKKLLSPHSVLQNKILDPSDVYKMISTYENTESFYPFSSLAVKLIQQAK

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Pfam
PF01671   ASFV_360
Interpro
IPR002595   ASFV_MGF360
ProteinModelPortal
PDB
3T71     E-value=1.01136,     Score=74

Ontologies

Subcellular Location

From MSLVP
Capsid

Topology

Length:
386
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
2.38839000000001
Exp number, first 60 AAs:
0.00902
Total prob of N-in:
0.03551
outside
1  -  386
 
 

Population Genetic Test Statistics

Pi
0.0728978
Theta
0.1481413
Tajima's D
-1.8024394
CLR
242.256531
Interpretation
Possibly Positive selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971    
China_AnhuiXCGQ_2018 Protein
AYW33968.1
China_ASFV-SY18_2018 Genetic Remain
Genetic Remain
AJL34191.1
CAN10109.1
Poland_Pol16_20186_o7_2016-2017 Protein
Protein
AXZ95788.1
AXZ95788.1
Poland_Pol16_20538_o9_2016-2017 Protein
AXZ95941.1
Poland_Pol16_20540_o10_2016-2017 Protein
AXZ95788.1
Poland_Pol16_29413_o23_2016-2017 Protein
AXZ95788.1
Poland_Pol17_03029_C201_2016-2017 Protein
AXZ95788.1
Poland_Pol17_04461_C210_2016-2017 Protein
AXZ95788.1
Poland_Pol17_05838_C220_2016-2017 Protein
AXZ95788.1
Poland_ASFV_POL_Podlaskie_2015 Protein
AXZ95788.1
Uganda_R8_2015 Protein
Protein
AXB49241.1
AXB49242.1
Uganda_R7_2015 Protein
Protein
AXB49415.1
AXB49416.1
Uganda_R25_2015 Protein
Protein
AXB49587.1
AXB49588.1
Uganda_N10_2015 Protein
Protein
AXB49760.1
AXB49761.1
Uganda_R35_2015 Protein
Protein
AXB49931.1
AXB49932.1
Estonia_2014 Protein
SPS73428.1
Italy_26544_OG10_2010 Protein
AJZ77077.1
Italy_47_Ss_2008_2008 Protein
AOO54324.1
Portugal_OURT_88.3_1988 Protein
CAN10366.1
Spain_E75_1975 Protein
CBH29110.1
Russia_Georgia_2007 Protein
CBW46670.1
Kenya_Tk1_2005 Protein
AJL34027.1
Kenya_Bus_2006 Protein
AJL34191.1
Russia_Odintsovo_2014 Protein
AXZ95788.1
Portugal_L60_1960 Protein
AIY22201.1
Portugal_NHV_1968 Protein
AIY22368.1
Russia_Kashino_2013 Protein
AXZ95788.1
Benin_1997 Protein
CAN10109.1
South_Africa_KNP_Pretorisuskop_1996 Protein
AXZ95788.1
South_Africa_MGR_Mkuzi_1979    
Malawi_Lil_1983 Protein
AXZ95788.1
Kenya_1950    
Namibia_Warthog_1980 Protein
AXZ95788.1
South_Africa_Warmbaths_1987 Protein
AXZ95788.1
Malawi_Tengani_1962    
China_HLJ_2018 Protein
QBH90493.1
China_LN_2018 Protein
QBH90678.1
China_wbBS01_2018 Protein
QDL88035.1
Ukraine_Kyiv_2014 Protein
Protein
QED21560.1
QED21561.1
Belgium_Etalle_wb_2018 Protein
QED90448.1
Lithuania_LT14_2014 Protein
QEY87810.1
South_Africa_1985 Protein
AXZ95788.1
South_Africa_2_2008    
Zambia_LIV_1983    
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