Strain

South_Africa_KNP_Pretorisuskop_1996 (Region: South Africa, Kruger National Park; Strain: Pretorisuskop/96/4; Date: 1996)

Gene

MGF 100-1R

Description

With frameshift mutation but translatable, MGF 100-1R

Location

AY261363.1(+):11987-12349

GenBank Accession

AJL34021.1

Full name

Protein MGF 100-1R

CDS

ATGGTTAGGTTATTTCGCAATCCGATAAAATGTATATTTTATCGTAGGTCTCGTAAAATCCAGGAAAAAAAATTACGGAAGAGTTTAAAAAAGCTAAATTTTTACCATCCTCCAGAAGATTGTTGTCAAATATATCGTTTGCTAGAAAATGTTCCTGGGGGAACTTACTTTATTACAGAAAATATGACGAATGATTTAATAATGGTCGTAAAGGATTCGGTGGATAAAAAAATTAAAAGCATTAAATTATATCTTCATGGAAGTTATATTAAGATTCATCAGCACTATTATATTAATATTTATATGTATCTTATGAGATATACCCAAATTTATAAATATCCCTTAATTTGTTTTAACAAATAT

Protein

MVRLFRNPIKCIFYRRSRKIQEKKLRKSLKKLNFYHPPEDCCQIYRLLENVPGGTYFITENMTNDLIMVVKDSVDKKIKSIKLYLHGSYIKIHQHYYINIYMYLMRYTQIYKYPLICFNKY

Function

Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.

Similarity

Belongs to the asfivirus MGF 100 family.

Keywords

Complete proteome

Feature

chain Protein MGF 100-1R

Uniprot

A0A0C5B212 A0A0C5AWI8 P0C9F0 P0C9F1 E0WMD2 A0A385KME1 + More
P0C9E9 P0C9F2 A9JLJ2 A0A0A1E0J4

Pubmed

25645905 21470447 18198370 25406173

EMBL

KM111294 AJL34021.1 KM111295 MH025916 MH025917 MH025918 + More
MH025919 MH025920 AJL34184.1 AXB49234.1 AXB49408.1 AXB49581.1 AXB49753.1 AXB49924.1 AY261360 AY261361 FR682468 CBW46660.1 MG939583 MG939586 MG939587 MG939588 AXZ95780.1 AXZ95960.1 AXZ95977.1 AXZ96072.1 AY261366 AY261363 AM712240 CAN10362.1 KM262845 AIY22364.1

Proteomes

UP000105860 UP000101566 UP000000861 UP000000860 UP000141072 UP000000858 + More
UP000000859 UP000108903 UP000110401

ProteinModelPortal

A0A0C5B212 A0A0C5AWI8 P0C9F0 P0C9F1 E0WMD2 A0A385KME1 + More
P0C9E9 P0C9F2 A9JLJ2 A0A0A1E0J4

PDB

6Q3G E-value=7.36456, Score=60

Ontologies

Subcellular Location

From MSLVP

Single-Pass Membrane

Topology

Length:

121

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.67056

Exp number, first 60 AAs:

0.00181

Total prob of N-in:

0.30352

outside

1 - 121

Population Genetic Test Statistics

Pi

0.2111464

Theta

0.2729182

Tajima's D

-0.939282

CLR

0.097016

Interpretation

No evidence of Selection

Multiple alignment of Orthologues

Gene Tree

Orthologous in Strains

Strain	Status	Gene
Spain_BA71_1971
China_AnhuiXCGQ_2018	Protein	AYW33961.1
China_ASFV-SY18_2018	Protein	CAN10362.1
Poland_Pol16_20186_o7_2016-2017	Protein	AXZ95780.1
Poland_Pol16_20538_o9_2016-2017	Protein	QGM12799.1
Poland_Pol16_20540_o10_2016-2017	Protein	QGM12799.1
Poland_Pol16_29413_o23_2016-2017	Protein	AXZ95960.1
Poland_Pol17_03029_C201_2016-2017	Protein	AXZ95977.1
Poland_Pol17_04461_C210_2016-2017	Protein	AXZ96072.1
Poland_Pol17_05838_C220_2016-2017	Protein	QGM12799.1
Poland_ASFV_POL_Podlaskie_2015	Protein	QGM12799.1
Uganda_R8_2015
Uganda_R7_2015
Uganda_R25_2015
Uganda_N10_2015
Uganda_R35_2015
Estonia_2014
Italy_26544_OG10_2010
Italy_47_Ss_2008_2008
Portugal_OURT_88.3_1988	Protein	CAN10362.1
Spain_E75_1975
Russia_Georgia_2007	Protein	CBW46660.1
Kenya_Tk1_2005
Kenya_Bus_2006
Russia_Odintsovo_2014	Protein	QGM12799.1
Portugal_L60_1960
Portugal_NHV_1968	Protein	AIY22364.1
Russia_Kashino_2013	Protein	QGM12799.1
Benin_1997
South_Africa_KNP_Pretorisuskop_1996	Protein	AJL34021.1
South_Africa_MGR_Mkuzi_1979	Protein	QGM12799.1
Malawi_Lil_1983
Kenya_1950
Namibia_Warthog_1980	Protein	QGM12799.1
South_Africa_Warmbaths_1987	Protein	QGM12799.1
Malawi_Tengani_1962	Protein	QGM12799.1
China_HLJ_2018	Protein	QBH90483.1
China_LN_2018	Protein	QBH90668.1
China_wbBS01_2018	Protein	QDL88025.1
Ukraine_Kyiv_2014	Protein	QED21553.1
Belgium_Etalle_wb_2018	Protein	QED90440.1
Lithuania_LT14_2014	Protein	QEY87799.1
South_Africa_1985
South_Africa_2_2008
Zambia_LIV_1983

Sequence