ASFVdb The African Swine Fever Virus Database
Strain
Benin_1997 (Region: Benin;  Strain: Benin 97/1;  Date: 1997)
Gene
MGF 110-12L
Description
Annotated in NCBI,  Member of multigene family 110 (Lis 119_2)
GenBank Accession
Full name
Protein MGF 110-11L       + More
Protein MGF 110-12L      
Protein MGF 360-1L      
Protein MGF 360-3L      
 

Sequence

CDS
ATGAAGGTTTTTCTAGGACTTTTACTAGGTTATTCAACCATCCTCATTCTTACATATCAATCACCAACAACCCAGTGGTGTTTTTATGAAATATCACTTAAAATACTTAATCATCATAGCATGGAAAAATGGAGGGATAAGAATTGGTCAATCATTATAAGGTATTATTGTTTTTACCTTGTATTTAGCTTTGCATTTGCTGGTTGCGTTGCATTTGCGATCTGCAAAAATCTACGACTGTGTACAACCATGAAATTACTTATGCTTTTGAATATTTTGGTTTTGTTATCTCAGCCAATTTTGAATAATTGA
Protein
MKVFLGLLLGYSTILILTYQSPTTQWCFYEISLKILNHHSMEKWRDKNWSIIIRYYCFYLVFSFAFAGCVAFAICKNLRLCTTMKLLMLLNILVLLSQPILNN

Summary

Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
Similarity
Belongs to the asfivirus MGF 110 family.
Keywords
Complete proteome   Glycoprotein   Host membrane   Membrane   Transmembrane   Transmembrane helix  
Feature
chain  Protein MGF 110-11L
Pfam
PF01639   v110
Interpro
IPR004848   V110_vir

Ontologies

Subcellular Location

From MSLVP
Multi-Pass Membrane
From Uniprot
Host membrane  

Topology

Length:
103
Number of predicted TMHs:
2
Exp number of AAs in TMHs:
55.40443
Exp number, first 60 AAs:
27.89
Total prob of N-in:
0.88242
POSSIBLE N-term signal
sequence
inside
1  -  6
TMhelix
7  -  29
outside
30  -  51
TMhelix
52  -  74
inside
75  -  103
 
 

Population Genetic Test Statistics

Pi
0.1204955
Theta
0.2277056
Tajima's D
-1.8712536
CLR
28.401887
Interpretation
Possibly Positive selection

Genomic alignment in the CDS region

 
 

Multiple alignment of Orthologues

 
 

Gene Tree

 
 

Orthologous in Strains

Strain Availability Status Gene
Spain_BA71_1971    
China_AnhuiXCGQ_2018 Protein
AYW33981.1
China_ASFV-SY18_2018 Protein
CAN10106.1
Poland_Pol16_20186_o7_2016-2017    
Poland_Pol16_20538_o9_2016-2017    
Poland_Pol16_20540_o10_2016-2017    
Poland_Pol16_29413_o23_2016-2017    
Poland_Pol17_03029_C201_2016-2017    
Poland_Pol17_04461_C210_2016-2017    
Poland_Pol17_05838_C220_2016-2017    
Poland_ASFV_POL_Podlaskie_2015    
Uganda_R8_2015 Protein
AXB49238.1
Uganda_R7_2015 Protein
AXB49412.1
Uganda_R25_2015 Protein
AXB49584.1
Uganda_N10_2015 Protein
AXB49757.1
Uganda_R35_2015 Protein
AXB49928.1
Estonia_2014    
Italy_26544_OG10_2010 Protein
AJZ77174.1
Italy_47_Ss_2008_2008 Protein
AOO54320.1
Portugal_OURT_88.3_1988    
Spain_E75_1975 Protein
CBH29108.1
Russia_Georgia_2007 Protein
CBW46667.1
Kenya_Tk1_2005 Protein
AJL34025.1
Kenya_Bus_2006 Protein
Protein
AJL34188.1
AJL34188.1
Russia_Odintsovo_2014    
Portugal_L60_1960 Protein
AIY22198.1
Portugal_NHV_1968    
Russia_Kashino_2013    
Benin_1997 Protein
CAN10106.1
South_Africa_KNP_Pretorisuskop_1996    
South_Africa_MGR_Mkuzi_1979    
Malawi_Lil_1983    
Kenya_1950    
Namibia_Warthog_1980    
South_Africa_Warmbaths_1987    
Malawi_Tengani_1962    
China_HLJ_2018 Protein
QBH90490.1
China_LN_2018 Protein
QBH90675.1
China_wbBS01_2018 Protein
QDL88032.1
Ukraine_Kyiv_2014 Protein
QED21558.1
Belgium_Etalle_wb_2018 Protein
QED90446.1
Lithuania_LT14_2014 Protein
QEY87806.1
South_Africa_1985    
South_Africa_2_2008    
Zambia_LIV_1983    
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